IT1261808B - Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi - Google Patents

Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi

Info

Publication number
IT1261808B
IT1261808B ITRM930441A ITRM930441A IT1261808B IT 1261808 B IT1261808 B IT 1261808B IT RM930441 A ITRM930441 A IT RM930441A IT RM930441 A ITRM930441 A IT RM930441A IT 1261808 B IT1261808 B IT 1261808B
Authority
IT
Italy
Prior art keywords
carnitine
dissods
convulsive
treatment
valproate
Prior art date
Application number
ITRM930441A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ITRM930441A0 publication Critical patent/ITRM930441A0/it
Priority to ITRM930441A priority Critical patent/IT1261808B/it
Priority to AT94830306T priority patent/ATE161718T1/de
Priority to ES94830306T priority patent/ES2111891T3/es
Priority to EP94830306A priority patent/EP0637449B1/en
Priority to DK94830306.0T priority patent/DK0637449T3/da
Priority to DE69407684T priority patent/DE69407684T2/de
Publication of ITRM930441A1 publication Critical patent/ITRM930441A1/it
Application granted granted Critical
Publication of IT1261808B publication Critical patent/IT1261808B/it
Priority to GR970402218T priority patent/GR3025845T3/el
Priority to HK98104925A priority patent/HK1005771A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

l'uso coordinato di L-carnitina o acil L-carnitine e valproato consente di ridurre drammaticamente la frequenza degli attacchi convulsivi in soggetti affetti da epilessia.
ITRM930441A 1993-07-06 1993-07-06 Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi IT1261808B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITRM930441A IT1261808B (it) 1993-07-06 1993-07-06 Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi
DK94830306.0T DK0637449T3 (da) 1993-07-06 1994-06-22 Anvendelse af L-carnitin eller acyl-L-carnitiner og valproat til behandling af anfaldslidelser
ES94830306T ES2111891T3 (es) 1993-07-06 1994-06-22 Empleo de l-carnitina o acil l-carnitinas y valproato para tratar trastornos epilepticos.
EP94830306A EP0637449B1 (en) 1993-07-06 1994-06-22 Use of L-carnitine or acyl L-carnitines and valproate for treating seizure disorders
AT94830306T ATE161718T1 (de) 1993-07-06 1994-06-22 Verwendung von l-carnitine oder acyl-l-carnitinen und valproat zur behandlung von anfallserkrankungen
DE69407684T DE69407684T2 (de) 1993-07-06 1994-06-22 Verwendung von L-Carnitine oder Acyl-L-Carnitinen und Valproat zur Behandlung von Anfallserkrankungen
GR970402218T GR3025845T3 (en) 1993-07-06 1998-01-08 Use of L-carnitine or acyl L-carnitines and valproate for treating seizure disorders.
HK98104925A HK1005771A1 (en) 1993-07-06 1998-06-05 Use of l-carnitine or acyl l-carnitines and valproate for treating seizure disorders

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM930441A IT1261808B (it) 1993-07-06 1993-07-06 Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi

Publications (3)

Publication Number Publication Date
ITRM930441A0 ITRM930441A0 (it) 1993-07-06
ITRM930441A1 ITRM930441A1 (it) 1995-01-06
IT1261808B true IT1261808B (it) 1996-06-03

Family

ID=11401844

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM930441A IT1261808B (it) 1993-07-06 1993-07-06 Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi

Country Status (8)

Country Link
EP (1) EP0637449B1 (it)
AT (1) ATE161718T1 (it)
DE (1) DE69407684T2 (it)
DK (1) DK0637449T3 (it)
ES (1) ES2111891T3 (it)
GR (1) GR3025845T3 (it)
HK (1) HK1005771A1 (it)
IT (1) IT1261808B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE03604B1 (et) * 1996-05-31 2002-02-15 Fassi Aldo L(-)-karnitiini ja alkanoüül-L(-)-karnitiini stabiilsed mittehügroskoopsed soolad, nende valmistamismeetod ja neid sooli sisaldavad tahked peroraalselt manustatavad kompositsioonid
EP0972516A1 (en) * 1998-06-25 2000-01-19 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Gastro-intestinal adverse effect-free composition comprising an L-carnitine replacement.
ITRM20010030A1 (it) * 2001-01-23 2002-07-23 Aldo Fassi Sali di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per la loro pr
GB0307860D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
US7456216B2 (en) * 2007-03-19 2008-11-25 Biolink Life Sciences, Inc. Methods for the preparation and formulation of l-carnitine valproate salts
US20110015267A1 (en) * 2009-07-20 2011-01-20 Deanna Jean Nelson Methods for the preparation and use of aqueous solutions of magnesium valproate hydrate and l-carnitine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3726945A1 (de) * 1987-08-13 1989-02-23 Dietl Hans L-carnitinderivate der valproinsaeure und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0637449B1 (en) 1998-01-07
EP0637449A1 (en) 1995-02-08
DK0637449T3 (da) 1998-05-25
ITRM930441A0 (it) 1993-07-06
ITRM930441A1 (it) 1995-01-06
DE69407684D1 (de) 1998-02-12
GR3025845T3 (en) 1998-04-30
ATE161718T1 (de) 1998-01-15
HK1005771A1 (en) 1999-01-22
DE69407684T2 (de) 1998-04-30
ES2111891T3 (es) 1998-03-16

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970609