TR199701289T2 - Karbapenemlerin esterleri - Google Patents
Karbapenemlerin esterleriInfo
- Publication number
- TR199701289T2 TR199701289T2 TR97/01289T TR9701289T TR199701289T2 TR 199701289 T2 TR199701289 T2 TR 199701289T2 TR 97/01289 T TR97/01289 T TR 97/01289T TR 9701289 T TR9701289 T TR 9701289T TR 199701289 T2 TR199701289 T2 TR 199701289T2
- Authority
- TR
- Turkey
- Prior art keywords
- group
- optionally substituted
- formula
- substituted
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
- C07D477/08—Modification of a carboxyl group directly attached in position 2, e.g. esterification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Asagidaki genel formül (I)'in bir bilesimi bakteryal enfeksiyonlarin tedavisinde yararlidir, burada R (a)'dir;Ra hidrojen, istege bagli olarak ikameli (C1-6) alkil ya da istege bagli olarak ikameli arildir; R ; hidrojen, istege bagli olarak ikameli arildir ya da Ra ve R birlikte ek hetero atomsuz, istege bagli olarak ikameli 5 ya da 6 elemanli heterosiklik halka olusturur; R1; ikamesiz ya da floro ile ikameli (C1-6) alkil istege bagli olarak kolayca ayrilabilen hidroksi koruma grubu ya da bir amino koruma grubu ile kolayca korunabilen bir amino grubu ile korunan bir hidroksi grubudur; R2 ya da metildir; ve R3 formül (i) (a) grubudan ve formül CH(Ra) O.CO.Rb'den olusan gruptan seçilir.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9508959.5A GB9508959D0 (en) | 1995-05-03 | 1995-05-03 | Novel compounds |
GBGB9508960.3A GB9508960D0 (en) | 1995-05-03 | 1995-05-03 | Novel compounds |
GBGB9508964.5A GB9508964D0 (en) | 1995-05-03 | 1995-05-03 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199701289T2 true TR199701289T2 (tr) | 1998-08-21 |
Family
ID=27267697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR97/01289T TR199701289T2 (tr) | 1995-05-03 | 1996-05-02 | Karbapenemlerin esterleri |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0823911A1 (tr) |
JP (1) | JPH11504912A (tr) |
KR (1) | KR19990008354A (tr) |
CN (1) | CN1184480A (tr) |
AU (1) | AU5814196A (tr) |
BR (1) | BR9608318A (tr) |
CA (1) | CA2217885A1 (tr) |
CZ (1) | CZ347697A3 (tr) |
HU (1) | HUP9801061A3 (tr) |
MX (1) | MX9708422A (tr) |
NO (1) | NO974995L (tr) |
PL (1) | PL323148A1 (tr) |
TR (1) | TR199701289T2 (tr) |
WO (1) | WO1996034869A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100771019B1 (ko) * | 2002-03-20 | 2007-10-29 | 주식회사 만도 | 브레이크 액압제어장치 |
GB0400329D0 (en) * | 2004-01-08 | 2004-02-11 | Glaxo Group Ltd | Novel processes |
GB0400405D0 (en) * | 2004-01-09 | 2004-02-11 | Glaxo Group Ltd | Novel processes |
JP2007039383A (ja) * | 2005-08-03 | 2007-02-15 | Dainippon Sumitomo Pharma Co Ltd | アリールカルバペネム化合物の製造方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1593524A (en) * | 1976-11-19 | 1981-07-15 | Merck & Co Inc | 1-carba-2-penem-3-carboxylic acids |
DK637888A (da) * | 1987-11-24 | 1989-05-25 | Hoffmann La Roche | Carboxylsyreestere |
GB8809534D0 (en) * | 1988-04-22 | 1988-05-25 | Beecham Group Plc | Novel compounds |
CN1167486A (zh) * | 1993-10-29 | 1997-12-10 | 史密斯克莱·比奇曼公司 | 2-(吡唑-3-基)碳代青霉烯衍生物 |
-
1996
- 1996-05-02 MX MX9708422A patent/MX9708422A/es unknown
- 1996-05-02 CA CA002217885A patent/CA2217885A1/en not_active Abandoned
- 1996-05-02 PL PL96323148A patent/PL323148A1/xx unknown
- 1996-05-02 EP EP96919680A patent/EP0823911A1/en not_active Withdrawn
- 1996-05-02 CN CN96194015A patent/CN1184480A/zh active Pending
- 1996-05-02 TR TR97/01289T patent/TR199701289T2/tr unknown
- 1996-05-02 AU AU58141/96A patent/AU5814196A/en not_active Abandoned
- 1996-05-02 KR KR1019970707880A patent/KR19990008354A/ko not_active Application Discontinuation
- 1996-05-02 BR BR9608318A patent/BR9608318A/pt unknown
- 1996-05-02 CZ CZ973476A patent/CZ347697A3/cs unknown
- 1996-05-02 JP JP8533022A patent/JPH11504912A/ja active Pending
- 1996-05-02 WO PCT/EP1996/001882 patent/WO1996034869A1/en not_active Application Discontinuation
- 1996-05-02 HU HU9801061A patent/HUP9801061A3/hu unknown
-
1997
- 1997-10-30 NO NO974995A patent/NO974995L/no unknown
Also Published As
Publication number | Publication date |
---|---|
JPH11504912A (ja) | 1999-05-11 |
MX9708422A (es) | 1998-02-28 |
EP0823911A1 (en) | 1998-02-18 |
WO1996034869A1 (en) | 1996-11-07 |
NO974995D0 (no) | 1997-10-30 |
CA2217885A1 (en) | 1996-11-07 |
CZ347697A3 (cs) | 1998-06-17 |
KR19990008354A (ko) | 1999-01-25 |
NO974995L (no) | 1997-10-30 |
CN1184480A (zh) | 1998-06-10 |
AU5814196A (en) | 1996-11-21 |
HUP9801061A3 (en) | 1999-01-28 |
HUP9801061A2 (hu) | 1998-08-28 |
BR9608318A (pt) | 1999-01-26 |
PL323148A1 (en) | 1998-03-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR199700844T1 (tr) | Pirazolil-Benzoil Türevleri. | |
DE69615002D1 (de) | Durch hetero-aromatische ring substituierte phenyloxazolidinone als antimikrobielles mittel | |
DE69919897D1 (en) | 4-oxo-1,4-dihydro-3-chinolincarboxamide als antivirale mittel | |
EA199800141A1 (ru) | Гетероциклические соединения | |
DK0918776T3 (da) | Totalsyntese af antitumor acylfulvener | |
TR199701728T1 (tr) | Sialil-Lewis X ve sialil-Lewis A taklitleri olarak digikosilatlanmis 1,-2-dioller. | |
DE69833797D1 (de) | Substituierte 2-benzylamino-2-phenyl-acetamidverbindungen | |
PT947504E (pt) | Derivados de vitamina d 16-eno | |
DE69719511T2 (de) | Antivirale 2,4-pyrimidindion-derivate und verfahren zu ihrer herstellung | |
GB9426090D0 (en) | Pharmaceutical compounds | |
TR199701289T2 (tr) | Karbapenemlerin esterleri | |
FI953784A0 (fi) | 3'-atsiridinoantrasykliinijohdannaiset | |
TR199700802T2 (tr) | Triazin türevleri. | |
ATE225335T1 (de) | Amide derivate als 5-ht1a liganden | |
TW354780B (en) | 2-disubstituted cyclohexenyl and cyclohexyl antimicrobial agents | |
HRP20010885B1 (en) | Ethanesulfonyl-piperidine derivatives | |
UA26459C2 (uk) | Іhгібітор впливу амілоїдhих білків | |
AU4486796A (en) | Imidazole derivatives, their preparation and their use as sadenosylmethionine decarboxylase (=samdc) inhibitors | |
AU8223991A (en) | New salts derived from dialkylaminoalkylsulphonyl-26 pristinamycin iib | |
DE69402021T2 (de) | Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren | |
TR199701286T1 (tr) | Karbapenemlerin esterleri. | |
TW349092B (en) | Substituted indole derivatives |