HUP9801061A3 - Esters of carbapenems, process for producing them and pharmaceutical compositions containing the same - Google Patents

Esters of carbapenems, process for producing them and pharmaceutical compositions containing the same

Info

Publication number
HUP9801061A3
HUP9801061A3 HU9801061A HUP9801061A HUP9801061A3 HU P9801061 A3 HUP9801061 A3 HU P9801061A3 HU 9801061 A HU9801061 A HU 9801061A HU P9801061 A HUP9801061 A HU P9801061A HU P9801061 A3 HUP9801061 A3 HU P9801061A3
Authority
HU
Hungary
Prior art keywords
carbapenems
esters
producing
same
pharmaceutical compositions
Prior art date
Application number
HU9801061A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9508960.3A external-priority patent/GB9508960D0/en
Priority claimed from GBGB9508959.5A external-priority patent/GB9508959D0/en
Priority claimed from GBGB9508964.5A external-priority patent/GB9508964D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HUP9801061A2 publication Critical patent/HUP9801061A2/hu
Publication of HUP9801061A3 publication Critical patent/HUP9801061A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • C07D477/06Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D477/08Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
HU9801061A 1995-05-03 1996-05-02 Esters of carbapenems, process for producing them and pharmaceutical compositions containing the same HUP9801061A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9508960.3A GB9508960D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508959.5A GB9508959D0 (en) 1995-05-03 1995-05-03 Novel compounds
GBGB9508964.5A GB9508964D0 (en) 1995-05-03 1995-05-03 Novel compounds

Publications (2)

Publication Number Publication Date
HUP9801061A2 HUP9801061A2 (hu) 1998-08-28
HUP9801061A3 true HUP9801061A3 (en) 1999-01-28

Family

ID=27267697

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801061A HUP9801061A3 (en) 1995-05-03 1996-05-02 Esters of carbapenems, process for producing them and pharmaceutical compositions containing the same

Country Status (14)

Country Link
EP (1) EP0823911A1 (hu)
JP (1) JPH11504912A (hu)
KR (1) KR19990008354A (hu)
CN (1) CN1184480A (hu)
AU (1) AU5814196A (hu)
BR (1) BR9608318A (hu)
CA (1) CA2217885A1 (hu)
CZ (1) CZ347697A3 (hu)
HU (1) HUP9801061A3 (hu)
MX (1) MX9708422A (hu)
NO (1) NO974995L (hu)
PL (1) PL323148A1 (hu)
TR (1) TR199701289T2 (hu)
WO (1) WO1996034869A1 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100771019B1 (ko) * 2002-03-20 2007-10-29 주식회사 만도 브레이크 액압제어장치
GB0400329D0 (en) * 2004-01-08 2004-02-11 Glaxo Group Ltd Novel processes
GB0400405D0 (en) * 2004-01-09 2004-02-11 Glaxo Group Ltd Novel processes
JP2007039383A (ja) * 2005-08-03 2007-02-15 Dainippon Sumitomo Pharma Co Ltd アリールカルバペネム化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DK637888A (da) * 1987-11-24 1989-05-25 Hoffmann La Roche Carboxylsyreestere
GB8809534D0 (en) * 1988-04-22 1988-05-25 Beecham Group Plc Novel compounds
SK53696A3 (en) * 1993-10-29 1996-10-02 Smithkline Beecham Plc Carbapenem derivatives, their preparation, pharmaceutical compositions containing them and their use

Also Published As

Publication number Publication date
CZ347697A3 (cs) 1998-06-17
CN1184480A (zh) 1998-06-10
MX9708422A (es) 1998-02-28
TR199701289T2 (xx) 1998-08-21
BR9608318A (pt) 1999-01-26
AU5814196A (en) 1996-11-21
JPH11504912A (ja) 1999-05-11
NO974995D0 (no) 1997-10-30
KR19990008354A (ko) 1999-01-25
HUP9801061A2 (hu) 1998-08-28
PL323148A1 (en) 1998-03-16
EP0823911A1 (en) 1998-02-18
CA2217885A1 (en) 1996-11-07
WO1996034869A1 (en) 1996-11-07
NO974995L (no) 1997-10-30

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