DE69402021T2 - Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren - Google Patents

Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren

Info

Publication number
DE69402021T2
DE69402021T2 DE69402021T DE69402021T DE69402021T2 DE 69402021 T2 DE69402021 T2 DE 69402021T2 DE 69402021 T DE69402021 T DE 69402021T DE 69402021 T DE69402021 T DE 69402021T DE 69402021 T2 DE69402021 T2 DE 69402021T2
Authority
DE
Germany
Prior art keywords
pct
aminooxy
branched
amino
decarboxylase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69402021T
Other languages
English (en)
Other versions
DE69402021D1 (en
Inventor
Joerg Frei
Jaroslav Stanek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE69402021D1 publication Critical patent/DE69402021D1/de
Application granted granted Critical
Publication of DE69402021T2 publication Critical patent/DE69402021T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69402021T 1993-04-13 1994-04-02 Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren Expired - Fee Related DE69402021T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH112993 1993-04-13
PCT/EP1994/001036 WO1994024094A1 (en) 1993-04-13 1994-04-02 Ornithine decarboxylase inhibiting branched aminooxy amino alkane derivatives

Publications (2)

Publication Number Publication Date
DE69402021D1 DE69402021D1 (en) 1997-04-17
DE69402021T2 true DE69402021T2 (de) 1997-10-30

Family

ID=4203174

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69402021T Expired - Fee Related DE69402021T2 (de) 1993-04-13 1994-04-02 Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren

Country Status (18)

Country Link
US (1) US5610195A (de)
EP (1) EP0644873B1 (de)
JP (1) JPH07508046A (de)
CN (1) CN1034930C (de)
AT (1) ATE150009T1 (de)
AU (1) AU673073B2 (de)
CA (1) CA2135781A1 (de)
CZ (1) CZ7995A3 (de)
DE (1) DE69402021T2 (de)
DK (1) DK0644873T3 (de)
ES (1) ES2102221T3 (de)
GR (1) GR3023429T3 (de)
HU (1) HUT72751A (de)
NZ (1) NZ265253A (de)
PL (1) PL306765A1 (de)
RU (1) RU95110939A (de)
SK (1) SK3795A3 (de)
WO (1) WO1994024094A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0644872T3 (da) * 1993-04-13 1997-10-06 Ciba Geigy Ag Cykliske aminooxy-forbindelser, som hæmmer ornithin-decarboxylase.
US20030185754A1 (en) * 2001-01-16 2003-10-02 Genset, S.A. Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists
US20030166554A1 (en) * 2001-01-16 2003-09-04 Genset, S.A. Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3137705A (en) * 1960-04-08 1964-06-16 Ciba Geigy Corp Hydroxylamino compounds
GB974163A (en) * 1960-04-08 1964-11-04 Ciba Ltd Manufacture of 1-amino-ªÏ-hydroxylamino-alkanes
US3869278A (en) * 1972-07-27 1975-03-04 Merrill Wilcox Hydroxylamines and derivatives thereof as abscission agents
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
DE3501616A1 (de) * 1985-01-17 1986-07-17 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von hydroxylamin-derivaten
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
GB8729521D0 (en) * 1987-12-18 1988-02-03 May & Baker Ltd New compositions of matter
EP0369944A1 (de) * 1988-11-18 1990-05-23 Ciba-Geigy Ag Substituierte Oxadiaminobutane
CA2014880A1 (en) * 1989-04-27 1990-10-27 Indu Sawhney Thiazole derivatives
NO903360L (no) * 1989-08-11 1991-02-12 Ici Pharma Antibiotiske forbindelser.
EP0483427A1 (de) * 1990-11-01 1992-05-06 The Procter & Gamble Company Deodorant-Präparat und Verfahren zur Desodorisierung mit Aminen
DK0644872T3 (da) * 1993-04-13 1997-10-06 Ciba Geigy Ag Cykliske aminooxy-forbindelser, som hæmmer ornithin-decarboxylase.

Also Published As

Publication number Publication date
RU95110939A (ru) 1996-10-27
JPH07508046A (ja) 1995-09-07
CN1104831A (zh) 1995-07-05
GR3023429T3 (en) 1997-08-29
HU9500095D0 (en) 1995-03-28
PL306765A1 (en) 1995-04-18
SK3795A3 (en) 1995-05-10
EP0644873B1 (de) 1997-03-12
NZ265253A (en) 1996-10-28
EP0644873A1 (de) 1995-03-29
US5610195A (en) 1997-03-11
AU673073B2 (en) 1996-10-24
ATE150009T1 (de) 1997-03-15
ES2102221T3 (es) 1997-07-16
CN1034930C (zh) 1997-05-21
DE69402021D1 (en) 1997-04-17
HUT72751A (en) 1996-05-28
DK0644873T3 (da) 1997-04-07
CA2135781A1 (en) 1994-10-27
AU6564694A (en) 1994-11-08
CZ7995A3 (en) 1995-10-18
WO1994024094A1 (en) 1994-10-27

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee