ATE150009T1 - Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren - Google Patents

Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren

Info

Publication number
ATE150009T1
ATE150009T1 AT94913517T AT94913517T ATE150009T1 AT E150009 T1 ATE150009 T1 AT E150009T1 AT 94913517 T AT94913517 T AT 94913517T AT 94913517 T AT94913517 T AT 94913517T AT E150009 T1 ATE150009 T1 AT E150009T1
Authority
AT
Austria
Prior art keywords
pct
ornithine decarboxylase
aminooxy
branched
amino
Prior art date
Application number
AT94913517T
Other languages
English (en)
Inventor
Joerg Frei
Jaroslav Stanek
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of ATE150009T1 publication Critical patent/ATE150009T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
AT94913517T 1993-04-13 1994-04-02 Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren ATE150009T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH112993 1993-04-13

Publications (1)

Publication Number Publication Date
ATE150009T1 true ATE150009T1 (de) 1997-03-15

Family

ID=4203174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94913517T ATE150009T1 (de) 1993-04-13 1994-04-02 Verzweigte aminooxy-amino-alkan-derivate als ornithin-decarboxylase inhibitoren

Country Status (18)

Country Link
US (1) US5610195A (de)
EP (1) EP0644873B1 (de)
JP (1) JPH07508046A (de)
CN (1) CN1034930C (de)
AT (1) ATE150009T1 (de)
AU (1) AU673073B2 (de)
CA (1) CA2135781A1 (de)
CZ (1) CZ7995A3 (de)
DE (1) DE69402021T2 (de)
DK (1) DK0644873T3 (de)
ES (1) ES2102221T3 (de)
GR (1) GR3023429T3 (de)
HU (1) HUT72751A (de)
NZ (1) NZ265253A (de)
PL (1) PL306765A1 (de)
RU (1) RU95110939A (de)
SK (1) SK3795A3 (de)
WO (1) WO1994024094A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0644872T3 (da) * 1993-04-13 1997-10-06 Ciba Geigy Ag Cykliske aminooxy-forbindelser, som hæmmer ornithin-decarboxylase.
US20030166554A1 (en) * 2001-01-16 2003-09-04 Genset, S.A. Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists
US20030185754A1 (en) * 2001-01-16 2003-10-02 Genset, S.A. Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3137705A (en) * 1960-04-08 1964-06-16 Ciba Geigy Corp Hydroxylamino compounds
GB974163A (en) * 1960-04-08 1964-11-04 Ciba Ltd Manufacture of 1-amino-ªÏ-hydroxylamino-alkanes
US3869278A (en) * 1972-07-27 1975-03-04 Merrill Wilcox Hydroxylamines and derivatives thereof as abscission agents
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
DE3501616A1 (de) * 1985-01-17 1986-07-17 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von hydroxylamin-derivaten
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
GB8729521D0 (en) * 1987-12-18 1988-02-03 May & Baker Ltd New compositions of matter
EP0369944A1 (de) * 1988-11-18 1990-05-23 Ciba-Geigy Ag Substituierte Oxadiaminobutane
CA2014880A1 (en) * 1989-04-27 1990-10-27 Indu Sawhney Thiazole derivatives
NO903360L (no) * 1989-08-11 1991-02-12 Ici Pharma Antibiotiske forbindelser.
EP0483427A1 (de) * 1990-11-01 1992-05-06 The Procter & Gamble Company Deodorant-Präparat und Verfahren zur Desodorisierung mit Aminen
DK0644872T3 (da) * 1993-04-13 1997-10-06 Ciba Geigy Ag Cykliske aminooxy-forbindelser, som hæmmer ornithin-decarboxylase.

Also Published As

Publication number Publication date
EP0644873B1 (de) 1997-03-12
EP0644873A1 (de) 1995-03-29
US5610195A (en) 1997-03-11
JPH07508046A (ja) 1995-09-07
HU9500095D0 (en) 1995-03-28
CA2135781A1 (en) 1994-10-27
SK3795A3 (en) 1995-05-10
HUT72751A (en) 1996-05-28
AU6564694A (en) 1994-11-08
CZ7995A3 (en) 1995-10-18
AU673073B2 (en) 1996-10-24
DE69402021D1 (en) 1997-04-17
NZ265253A (en) 1996-10-28
DK0644873T3 (da) 1997-04-07
CN1034930C (zh) 1997-05-21
DE69402021T2 (de) 1997-10-30
GR3023429T3 (en) 1997-08-29
WO1994024094A1 (en) 1994-10-27
RU95110939A (ru) 1996-10-27
PL306765A1 (en) 1995-04-18
CN1104831A (zh) 1995-07-05
ES2102221T3 (es) 1997-07-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee