TNSN90027A1 - Procede de preparation de peptides sdk - Google Patents

Procede de preparation de peptides sdk

Info

Publication number
TNSN90027A1
TNSN90027A1 TNTNSN90027A TNSN90027A TNSN90027A1 TN SN90027 A1 TNSN90027 A1 TN SN90027A1 TN TNSN90027 A TNTNSN90027 A TN TNSN90027A TN SN90027 A TNSN90027 A TN SN90027A TN SN90027 A1 TNSN90027 A1 TN SN90027A1
Authority
TN
Tunisia
Prior art keywords
obzl
boc
peptides
preparation
sdk
Prior art date
Application number
TNTNSN90027A
Other languages
English (en)
Inventor
Lenfant Maryse
Thierry Josiane
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of TNSN90027A1 publication Critical patent/TNSN90027A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'INVENTION CONCERNE UN PROCEDE DE PREPARATION DE PEPTIDES DE FORMULE GENERALE H2 - W - SER - ASP - LYS - X- OH, CONSISTANT A EFFECTUER, PAR LES VOIES DE SYNTHESE HABITUELLES, LA SEQUENCE REACTIONNELLES SUIVANTE: I BOC K(Z) - X ( ) - OH, II BOC D(OBZL) - D(OBZL) - K(Z) - X( ) - OH, III BOC S (BZL)-D(OBZL)-K(Z)-X( )-OH, IV BOC W( ) - S(BZL) - D(OBZL) - K(Z) - X( ) - OH, SOIT SELON LA METHODE DE L'ANHYDRIDE MIXTE, EN UTILISANT DU CHLOROFORMATE D'ISOBUTYLE, SOIT SELON LA METHODE DES ESTERS ACTIFS, EN UTILISANT LES ESTERS DU N-HYDROXY SUCCINIMIDE
TNTNSN90027A 1989-03-11 1990-03-08 Procede de preparation de peptides sdk TNSN90027A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898905606A GB8905606D0 (en) 1989-03-11 1989-03-11 Peptides

Publications (1)

Publication Number Publication Date
TNSN90027A1 true TNSN90027A1 (fr) 1991-03-05

Family

ID=10653152

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN90027A TNSN90027A1 (fr) 1989-03-11 1990-03-08 Procede de preparation de peptides sdk

Country Status (32)

Country Link
US (1) US5112811A (fr)
JP (1) JPH0347197A (fr)
KR (1) KR0133850B1 (fr)
AR (1) AR245139A1 (fr)
AT (1) AT402822B (fr)
AU (1) AU631197B2 (fr)
BE (1) BE1003996A3 (fr)
CA (1) CA2011874C (fr)
CH (1) CH680666A5 (fr)
DE (1) DE4007605B4 (fr)
DK (1) DK173932B1 (fr)
ES (1) ES2023746A6 (fr)
FI (1) FI901196A0 (fr)
FR (2) FR2644065B1 (fr)
GB (2) GB8905606D0 (fr)
GR (1) GR1000344B (fr)
HK (1) HK95392A (fr)
IE (1) IE64762B1 (fr)
IN (1) IN173870B (fr)
IT (1) IT1240933B (fr)
LU (1) LU87696A1 (fr)
MA (1) MA21770A1 (fr)
MY (1) MY106274A (fr)
NL (1) NL194918C (fr)
NO (1) NO901129L (fr)
NZ (1) NZ232815A (fr)
OA (1) OA09197A (fr)
PT (1) PT93380B (fr)
SE (1) SE9000793L (fr)
SG (1) SG91892G (fr)
TN (1) TNSN90027A1 (fr)
ZA (1) ZA901718B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK31991D0 (da) * 1991-02-25 1991-02-25 Carlbiotech Ltd As Peptid og farmaceutisk praeparat indeholdende et saadant peptid
GB9211668D0 (en) * 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
DE4224509C2 (de) * 1992-07-24 1995-04-20 Ruhenstroth Bauer Gerhard Prof Wirkstoff zur Hemmung der Proliferationsrate von Leberzellen
RU2302870C1 (ru) * 2006-06-22 2007-07-20 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Средство, обладающее геропротекторной активностью, и способ его получения

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US216088A (en) * 1879-06-03 Improvement in bale-ties
DE2602443A1 (de) * 1975-04-04 1976-10-21 Univ California Biologisch aktive polypeptide
US4816449A (en) * 1984-08-09 1989-03-28 Immunetech Pharmaceuticals Immunotherapeutic anti-inflammatory peptide agents
FR2565985B1 (fr) * 1984-06-19 1987-09-25 Rhone Poulenc Sante Nouvelles substances biologiquement actives obtenues a partir de la caseine bovine, leur procede de preparation et les compositions qui les contiennent
AU589919B2 (en) * 1984-10-15 1989-10-26 Cetus Corp Human tumor necrosis factor
FR2601678B1 (fr) * 1986-07-18 1989-11-24 Inst Nat Sante Rech Med Peptides comprenant la sequence seryl-aspartyl-lysyl-prolyle, procede pour l'extraction du tetrapeptide correspondant, et applications, notamment a la protection de la moelle osseuse au cours de traitements anticancereux par la chimiotherapie
FR2622587B1 (fr) * 1987-10-30 1990-12-21 Inst Vaisseaux Sang Peptide lysyl-arginyl-aspartyl-serine et ses applications en tant que medicament, notamment antithrombotique
JPH0742313B2 (ja) * 1988-03-28 1995-05-10 日立化成工業株式会社 新規ペプチド、その塩及びペプチド性抗アレルギー剤

Also Published As

Publication number Publication date
JPH0347197A (ja) 1991-02-28
ES2023746A6 (es) 1992-02-01
FR2644065B1 (fr) 1994-10-07
CH680666A5 (en) 1992-10-15
NL9000551A (nl) 1990-10-01
DK173932B1 (da) 2002-02-25
GR1000344B (el) 1992-06-25
NO901129L (no) 1990-09-12
ZA901718B (en) 1990-12-28
NZ232815A (en) 1992-06-25
AT402822B (de) 1997-09-25
KR900014426A (ko) 1990-10-23
SE9000793L (sv) 1990-09-12
CA2011874A1 (fr) 1990-09-11
LU87696A1 (fr) 1990-07-24
IT1240933B (it) 1993-12-27
PT93380A (pt) 1990-11-07
NL194918C (nl) 2003-07-04
HK95392A (en) 1992-12-04
IT9019630A1 (it) 1991-09-09
SG91892G (en) 1992-12-04
DE4007605A1 (de) 1990-09-13
IT9019630A0 (it) 1990-03-09
FR2644164A1 (fr) 1990-09-14
GB9005069D0 (en) 1990-05-02
DK62690D0 (da) 1990-03-09
NL194918B (nl) 2003-03-03
MY106274A (en) 1995-04-29
AU631197B2 (en) 1992-11-19
KR0133850B1 (ko) 1998-04-21
GB8905606D0 (en) 1989-04-26
FI901196A0 (fi) 1990-03-09
IN173870B (fr) 1994-07-30
OA09197A (fr) 1992-06-30
CA2011874C (fr) 1998-07-21
US5112811A (en) 1992-05-12
FR2644164B1 (fr) 1995-03-17
IE64762B1 (en) 1995-09-06
BE1003996A3 (fr) 1992-09-08
GB2228937A (en) 1990-09-12
AR245139A1 (es) 1993-12-30
DE4007605B4 (de) 2006-03-23
GR900100164A (en) 1990-07-31
AU5117590A (en) 1990-09-13
PT93380B (pt) 1997-01-31
SE9000793D0 (sv) 1990-03-06
ATA53290A (de) 1997-01-15
DK62690A (da) 1990-09-12
IE900850L (en) 1990-09-11
MA21770A1 (fr) 1990-10-01
FR2644065A1 (fr) 1990-09-14
GB2228937B (en) 1992-07-08
NO901129D0 (no) 1990-03-09

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