SU942599A3 - Способ получени пентагидрата (6R,7R)-7-/(Z)-2-(2-аминотиазол-4-ил)-2-(2-карбоксипроп-2-оксиимино)-ацетамидо/-3-(1-пиридинийметил)-цеф-3-ем-4-карбоксилата - Google Patents
Способ получени пентагидрата (6R,7R)-7-/(Z)-2-(2-аминотиазол-4-ил)-2-(2-карбоксипроп-2-оксиимино)-ацетамидо/-3-(1-пиридинийметил)-цеф-3-ем-4-карбоксилата Download PDFInfo
- Publication number
- SU942599A3 SU942599A3 SU802987392A SU2987392A SU942599A3 SU 942599 A3 SU942599 A3 SU 942599A3 SU 802987392 A SU802987392 A SU 802987392A SU 2987392 A SU2987392 A SU 2987392A SU 942599 A3 SU942599 A3 SU 942599A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- solution
- pentahydrate
- pyridiniummethyl
- carboxyprop
- aminothiazol
- Prior art date
Links
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- 230000003115 biocidal effect Effects 0.000 claims abstract description 3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7934204 | 1979-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU942599A3 true SU942599A3 (ru) | 1982-07-07 |
Family
ID=10508246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU802987392A SU942599A3 (ru) | 1979-10-02 | 1980-10-01 | Способ получени пентагидрата (6R,7R)-7-/(Z)-2-(2-аминотиазол-4-ил)-2-(2-карбоксипроп-2-оксиимино)-ацетамидо/-3-(1-пиридинийметил)-цеф-3-ем-4-карбоксилата |
Country Status (36)
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443444A (en) * | 1980-08-11 | 1984-04-17 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| US4427677A (en) | 1980-12-31 | 1984-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| US4474954A (en) * | 1981-12-07 | 1984-10-02 | Bristol-Myers Company | Intermediates for cephalosporin derivatives |
| US4394503A (en) | 1981-12-07 | 1983-07-19 | Bristol-Myers Company | Cephalosporin derivatives |
| JPS58198489A (ja) * | 1982-05-14 | 1983-11-18 | Meiji Seika Kaisha Ltd | ７β−（２Ｄ−２−アミノ−２−カルボキシエチルチオアセトアミド）−７α−メトキシ−３−（１−メチル−１Ｈ−テトラゾ−ル−５−イル）−チオメチル−３−セフエム−４−カルボン酸ナトリウム塩の七水和物及びその製造方法 |
| ES8502863A1 (es) * | 1982-09-10 | 1985-02-01 | Glaxo Group Ltd | Un procedimiento para la produccion de un recipiente hermeticamente cerrado que contiene al menos un antibiotico de beta-lactama. |
| DE3313816A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
| DE3313818A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
| GB8406218D0 (en) * | 1984-03-09 | 1984-04-11 | Glaxo Group Ltd | Process |
| US4537959A (en) * | 1984-03-26 | 1985-08-27 | Eli Lilly And Company | Crystalline cephalosporin antibiotic salt |
| JPS60231683A (ja) * | 1984-05-02 | 1985-11-18 | Teijin Ltd | セフアロスポリン誘導体その製造法及びそれを有効成分とする抗菌剤 |
| US4616080A (en) * | 1984-07-02 | 1986-10-07 | Eli Lilly And Company | Simplified process of forming crystalline ceftazidime pentahydrate |
| US4626534A (en) * | 1984-07-23 | 1986-12-02 | Eli Lilly And Company | Pharmaceutical formulation |
| DE3577656D1 (de) * | 1984-07-23 | 1990-06-21 | Lilly Co Eli | Pharmazeutische zusammensetzungen von ceftazidim. |
| ATE60607T1 (de) * | 1984-11-08 | 1991-02-15 | Lilly Co Eli | Verfahren zur herstellung von kristallinischem ceftazidime-pentahydrat. |
| US4659813A (en) * | 1984-11-08 | 1987-04-21 | Eli Lilly And Company | Crystallization process for ceftazidime derivative |
| US4910301A (en) * | 1985-08-05 | 1990-03-20 | Bristol-Myers Company | Cefepime cephalosporin salts |
| US4994451A (en) * | 1988-01-19 | 1991-02-19 | Bristol-Myers Company | Cephalosporin salts and injectable compositions |
| US5244891A (en) * | 1985-08-05 | 1993-09-14 | Bristol-Myers Squibb Company | Injectable compositions of cefepime dihydrochloride hydrate |
| US4954624A (en) * | 1986-10-07 | 1990-09-04 | Sandoz Ltd. | Process for the production of cephalosporin derivatives |
| AT387390B (de) * | 1986-10-07 | 1989-01-10 | Biochemie Gmbh | Verfahren zur herstellung des antibiotikums (6r,7r)-7-(2-(2-amino-4-thiazolyl)-2-(2-carboxy |
| JP2533151B2 (ja) * | 1987-02-02 | 1996-09-11 | イーライ・リリー・アンド・カンパニー | 抗生物質製造の改良法 |
| US5021564A (en) * | 1987-02-02 | 1991-06-04 | Eli Lilly And Company | Process for preparing ceftazidime pentahydrate |
| WO1988010262A1 (en) * | 1987-06-25 | 1988-12-29 | Banyu Pharmaceutical Co., Ltd. | Crystalline cephalosporin compound |
| DE3788279T2 (de) * | 1987-06-25 | 1994-06-16 | Banyu Pharma Co Ltd | Kristalline cephalosporinzusammensetzungen, verfahren und zwischenprodukte für ihre herstellung. |
| GB8802622D0 (en) * | 1988-02-05 | 1988-03-02 | Glaxo Group Ltd | Chemical compound |
| KR940000112B1 (ko) * | 1990-07-05 | 1994-01-05 | 주식회사 대웅제약 | 신규의 3-치환 세펨화합물 및 그의 제조방법 |
| US5831085A (en) * | 1997-01-16 | 1998-11-03 | Lupin Laboratories Limited | Process for manufacture of cephalosporin such as ceftazidime and intermediate thereof |
| CN1328281C (zh) * | 2004-11-16 | 2007-07-25 | 广州白云山制药股份有限公司 | 头孢他啶的纯化方法 |
| CN102924483B (zh) * | 2012-10-31 | 2015-06-17 | 海南合瑞制药股份有限公司 | 一种头孢他啶晶体化合物、其制备方法及其无菌混合粉形式的药物组合物 |
| CN102875576A (zh) * | 2012-10-31 | 2013-01-16 | 苏州致君万庆药业有限公司 | 一种抗菌素头孢他啶的合成、注射用头孢他啶及其制备方法 |
| CN104876949A (zh) * | 2015-05-28 | 2015-09-02 | 浙江长典医药有限公司 | 一种小儿用头孢他啶化合物实体及其制剂 |
| CN106420658A (zh) * | 2016-09-23 | 2017-02-22 | 临沂草之美医药科技有限公司 | 一种治疗外科手术感染的药物头孢他啶胶囊 |
| CN109111467A (zh) * | 2017-06-22 | 2019-01-01 | 宁应 | 一种51/4水头孢他啶化合物及其药物组合物制剂 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR228726A1 (es) * | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
-
1980
- 1980-09-09 US US06/185,883 patent/US4329453A/en not_active Expired - Lifetime
- 1980-10-01 DE DE3037102A patent/DE3037102C2/de not_active Expired
- 1980-10-01 IT IT49783/80A patent/IT1144006B/it active Protection Beyond IP Right Term
- 1980-10-01 BE BE0/202301A patent/BE885489A/fr not_active IP Right Cessation
- 1980-10-01 FI FI803126A patent/FI71157C/fi not_active IP Right Cessation
- 1980-10-01 ZA ZA00806081A patent/ZA806081B/xx unknown
- 1980-10-01 MX MX809068U patent/MX6545E/es unknown
- 1980-10-01 DK DK414780A patent/DK155525C/da not_active IP Right Cessation
- 1980-10-01 BG BG049206A patent/BG33586A3/xx unknown
- 1980-10-01 NO NO802913A patent/NO156246C/no unknown
- 1980-10-01 HU HU802393A patent/HU184835B/hu unknown
- 1980-10-01 SE SE8006861A patent/SE449614B/sv not_active IP Right Cessation
- 1980-10-01 JP JP13822480A patent/JPS5657791A/ja active Granted
- 1980-10-01 CA CA000361346A patent/CA1142919A/en not_active Expired
- 1980-10-01 AU AU62882/80A patent/AU539519B2/en not_active Expired
- 1980-10-01 CY CY1338A patent/CY1338A/en unknown
- 1980-10-01 SU SU802987392A patent/SU942599A3/ru active
- 1980-10-01 GB GB8031703A patent/GB2063871B/en not_active Expired
- 1980-10-01 GR GR63023A patent/GR69123B/el unknown
- 1980-10-01 DD DD80224266A patent/DD153376A5/de not_active IP Right Cessation
- 1980-10-01 AT AT0490080A patent/AT368161B/de not_active IP Right Cessation
- 1980-10-01 NL NLAANVRAGE8005443,A patent/NL190329C/xx not_active IP Right Cessation
- 1980-10-01 ES ES495534A patent/ES495534A0/es active Granted
- 1980-10-01 UA UA2987392A patent/UA7208A1/uk unknown
- 1980-10-01 FR FR8021033A patent/FR2466467A1/fr active Granted
- 1980-10-01 CH CH734180A patent/CH645118A5/de not_active IP Right Cessation
- 1980-10-01 CS CS806627A patent/CS214721B2/cs unknown
- 1980-10-01 RO RO102255A patent/RO82721B/ro unknown
- 1980-10-01 PL PL1980227019A patent/PL126606B1/pl unknown
- 1980-10-01 YU YU2497/80A patent/YU42357B/xx unknown
- 1980-10-01 PT PT71860A patent/PT71860B/pt unknown
- 1980-10-02 KR KR1019800003810A patent/KR840001776B1/ko not_active Expired
-
1985
- 1985-12-30 MY MY315/85A patent/MY8500315A/xx unknown
-
1986
- 1986-05-29 KE KE3641A patent/KE3641A/xx unknown
- 1986-10-16 HK HK786/86A patent/HK78686A/xx not_active IP Right Cessation
-
1994
- 1994-05-26 EC EC1994001099A patent/ECSP941099A/es unknown
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