ATE60607T1 - Verfahren zur herstellung von kristallinischem ceftazidime-pentahydrat. - Google Patents

Verfahren zur herstellung von kristallinischem ceftazidime-pentahydrat.

Info

Publication number
ATE60607T1
ATE60607T1 AT85308016T AT85308016T ATE60607T1 AT E60607 T1 ATE60607 T1 AT E60607T1 AT 85308016 T AT85308016 T AT 85308016T AT 85308016 T AT85308016 T AT 85308016T AT E60607 T1 ATE60607 T1 AT E60607T1
Authority
AT
Austria
Prior art keywords
ceftazidime
pentahydrate
crystalline pentahydrate
optimum
crystalline
Prior art date
Application number
AT85308016T
Other languages
English (en)
Inventor
Ronald Clay Browning
Melvin Gale Pleiss Jr
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE60607T1 publication Critical patent/ATE60607T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT85308016T 1984-11-08 1985-11-05 Verfahren zur herstellung von kristallinischem ceftazidime-pentahydrat. ATE60607T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66948284A 1984-11-08 1984-11-08
EP85308016A EP0187450B1 (de) 1984-11-08 1985-11-05 Verfahren zur Herstellung von kristallinischem Ceftazidime-Pentahydrat

Publications (1)

Publication Number Publication Date
ATE60607T1 true ATE60607T1 (de) 1991-02-15

Family

ID=24686483

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85308016T ATE60607T1 (de) 1984-11-08 1985-11-05 Verfahren zur herstellung von kristallinischem ceftazidime-pentahydrat.

Country Status (8)

Country Link
EP (1) EP0187450B1 (de)
JP (1) JPH0649703B2 (de)
AT (1) ATE60607T1 (de)
CA (1) CA1239389A (de)
DE (1) DE3581619D1 (de)
HK (1) HK62791A (de)
IE (1) IE58790B1 (de)
SG (1) SG57891G (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954624A (en) * 1986-10-07 1990-09-04 Sandoz Ltd. Process for the production of cephalosporin derivatives
AT387390B (de) * 1986-10-07 1989-01-10 Biochemie Gmbh Verfahren zur herstellung des antibiotikums (6r,7r)-7-(2-(2-amino-4-thiazolyl)-2-(2-carboxy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic

Also Published As

Publication number Publication date
EP0187450A3 (en) 1987-08-12
SG57891G (en) 1991-08-23
JPS61115088A (ja) 1986-06-02
DE3581619D1 (de) 1991-03-07
IE852766L (en) 1986-05-08
EP0187450B1 (de) 1991-01-30
HK62791A (en) 1991-08-16
EP0187450A2 (de) 1986-07-16
JPH0649703B2 (ja) 1994-06-29
IE58790B1 (en) 1993-11-17
CA1239389A (en) 1988-07-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time