SU1565346A3 - Способ получени производных 2,3,4,5,6,7-гексагидро-2,7-метано-1,5-бензоксазонина - Google Patents

Способ получени производных 2,3,4,5,6,7-гексагидро-2,7-метано-1,5-бензоксазонина Download PDF

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Publication number
SU1565346A3
SU1565346A3 SU874203240A SU4203240A SU1565346A3 SU 1565346 A3 SU1565346 A3 SU 1565346A3 SU 874203240 A SU874203240 A SU 874203240A SU 4203240 A SU4203240 A SU 4203240A SU 1565346 A3 SU1565346 A3 SU 1565346A3
Authority
SU
USSR - Soviet Union
Prior art keywords
substance
animals
benzoxazonine
naloxone
tramadol
Prior art date
Application number
SU874203240A
Other languages
English (en)
Russian (ru)
Inventor
Айден Фридрих
Гмайнер Петер
Шунеманн Юрген
Original Assignee
Др.Мадаус Гмбх Унд Ко (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Др.Мадаус Гмбх Унд Ко (Фирма) filed Critical Др.Мадаус Гмбх Унд Ко (Фирма)
Application granted granted Critical
Publication of SU1565346A3 publication Critical patent/SU1565346A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SU874203240A 1986-09-08 1987-09-07 Способ получени производных 2,3,4,5,6,7-гексагидро-2,7-метано-1,5-бензоксазонина SU1565346A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863630539 DE3630539A1 (de) 1986-09-08 1986-09-08 Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten

Publications (1)

Publication Number Publication Date
SU1565346A3 true SU1565346A3 (ru) 1990-05-15

Family

ID=6309142

Family Applications (1)

Application Number Title Priority Date Filing Date
SU874203240A SU1565346A3 (ru) 1986-09-08 1987-09-07 Способ получени производных 2,3,4,5,6,7-гексагидро-2,7-метано-1,5-бензоксазонина

Country Status (29)

Country Link
US (1) US4859664A (https=)
JP (1) JPS6377882A (https=)
KR (1) KR910002566B1 (https=)
CN (1) CN1020103C (https=)
AR (1) AR243190A1 (https=)
AT (1) ATA185987A (https=)
AU (1) AU590443B2 (https=)
BE (1) BE1002121A4 (https=)
CH (1) CH675723A5 (https=)
CS (1) CS621687A2 (https=)
DD (1) DD275052A1 (https=)
DE (1) DE3630539A1 (https=)
DK (1) DK464487A (https=)
ES (1) ES2013322A6 (https=)
FI (1) FI88800C (https=)
FR (1) FR2603587B1 (https=)
GB (1) GB2194786B (https=)
GR (1) GR871209B (https=)
HU (1) HU203106B (https=)
IL (1) IL83156A (https=)
IT (1) IT1228437B (https=)
NL (1) NL8701938A (https=)
NO (1) NO168530C (https=)
PL (1) PL154258B1 (https=)
PT (1) PT85656B (https=)
SE (1) SE8703343L (https=)
SU (1) SU1565346A3 (https=)
YU (1) YU46068B (https=)
ZA (1) ZA876657B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1320486C (en) * 1988-06-01 1993-07-20 John J. Lafferty .alpha. -adrenergic receptor antagonists
US4959360A (en) * 1988-06-01 1990-09-25 Smithkline Beecham Corporation α-adrenergic receptor antagonists
US4963547A (en) * 1988-06-01 1990-10-16 Smithkline Beecham Corporation Alpha-andrenergic receptor antagonists and use thereas
ES2057121T3 (es) * 1988-06-01 1994-10-16 Smithkline Beecham Corp Antagonistas de los receptores alfa-adrenergicos.
EP0344979B1 (en) * 1988-06-01 1994-11-09 Smithkline Beecham Corporation Alfa-adrenergic receptor antagonists
DE4102103A1 (de) * 1991-01-25 1992-08-20 Bayer Ag Substituierte benzoxazepine und benzthiazepine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5248645A (en) * 1992-09-01 1993-09-28 Phillips Petroleum Company Ethylene oligomerization

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124583A (en) * 1964-03-10 Substituted derivatives of
US3118900A (en) * 1962-01-15 1964-01-21 Abbott Lab Substituted derivatives of 3-aza-6, 7-benzo-8-oxa-5-phenylbicyclo[3.3.1]-nonane
US3401166A (en) * 1966-08-01 1968-09-10 Squibb & Sons Inc Therapeutically active benzothiazines
US3446820A (en) * 1967-04-03 1969-05-27 Rexall Drug Chemical Substituted benzoxazocines and intermediates
US3869475A (en) * 1973-04-05 1975-03-04 Yissum Res Dev Co 2,6-methano-benzoxacin compounds
JPS50106985A (https=) * 1973-05-08 1975-08-22
US4100277A (en) * 1976-11-08 1978-07-11 American Home Products Corporation 4,1-Benzoxazonine derivatives and process therefor
US4315006A (en) * 1979-08-09 1982-02-09 Glaxo Group Limited Benzoxocin derivatives having anxiolytic and anti-convulsant activities

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент DE № 2422309, кл. С 07 D 223/14, опублик, 1977. *

Also Published As

Publication number Publication date
IL83156A (en) 1992-12-01
FI873852A0 (fi) 1987-09-07
IT1228437B (it) 1991-06-17
HUT50180A (en) 1989-12-28
DE3630539A1 (de) 1988-03-10
HU203106B (en) 1991-05-28
DK464487D0 (da) 1987-09-07
SE8703343D0 (sv) 1987-08-28
ATA185987A (de) 1994-05-15
FI88800B (fi) 1993-03-31
IL83156A0 (en) 1987-12-31
YU46068B (sh) 1992-12-21
DK464487A (da) 1988-03-09
AU7816287A (en) 1988-03-10
NO873727D0 (no) 1987-09-07
PT85656B (pt) 1990-05-31
NO873727L (no) 1988-03-09
GB2194786B (en) 1991-01-02
GB8716668D0 (en) 1987-08-19
FR2603587B1 (fr) 1991-02-01
US4859664A (en) 1989-08-22
PT85656A (en) 1987-10-01
GR871209B (en) 1987-11-30
NO168530C (no) 1992-03-04
PL267628A1 (en) 1989-06-12
CH675723A5 (https=) 1990-10-31
CN1020103C (zh) 1993-03-17
KR910002566B1 (ko) 1991-04-26
AU590443B2 (en) 1989-11-02
AR243190A1 (es) 1993-07-30
IT8721436A0 (it) 1987-07-24
FI873852L (fi) 1988-03-09
NO168530B (no) 1991-11-25
FI88800C (fi) 1993-07-12
ES2013322A6 (es) 1990-05-01
PL154258B1 (en) 1991-07-31
FR2603587A1 (fr) 1988-03-11
CN87106267A (zh) 1988-04-13
BE1002121A4 (fr) 1990-07-17
GB2194786A (en) 1988-03-16
SE8703343L (sv) 1988-03-09
CS621687A2 (en) 1990-09-12
JPS6377882A (ja) 1988-04-08
JPH0319236B2 (https=) 1991-03-14
KR880003945A (ko) 1988-05-31
ZA876657B (en) 1988-03-08
DD275052A1 (de) 1990-01-10
NL8701938A (nl) 1988-04-05

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