ATE72447T1 - Chartreusinderivate und salze, diese enthaltende antitumorzusammensetzungen und verfahren zu ihrer herstellung. - Google Patents
Chartreusinderivate und salze, diese enthaltende antitumorzusammensetzungen und verfahren zu ihrer herstellung.Info
- Publication number
- ATE72447T1 ATE72447T1 AT86114562T AT86114562T ATE72447T1 AT E72447 T1 ATE72447 T1 AT E72447T1 AT 86114562 T AT86114562 T AT 86114562T AT 86114562 T AT86114562 T AT 86114562T AT E72447 T1 ATE72447 T1 AT E72447T1
- Authority
- AT
- Austria
- Prior art keywords
- chartreus
- individuals
- salts
- processes
- preparation
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- PONPPNYZKHNPKZ-RYBWXQSLSA-N Chartreusin Chemical class O[C@@H]1[C@@H](OC)[C@@H](O)[C@@H](C)O[C@@H]1O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](C)O[C@H]1OC1=CC=CC2=C(O)C(C(O3)=O)=C4C5=C3C=CC(C)=C5C(=O)OC4=C12 PONPPNYZKHNPKZ-RYBWXQSLSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001647 drug administration Methods 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Fireproofing Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23683385 | 1985-10-23 | ||
| EP86114562A EP0219852B1 (de) | 1985-10-23 | 1986-10-21 | Chartreusinderivate und Salze, diese enthaltende Antitumorzusammensetzungen und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE72447T1 true ATE72447T1 (de) | 1992-02-15 |
Family
ID=17006457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86114562T ATE72447T1 (de) | 1985-10-23 | 1986-10-21 | Chartreusinderivate und salze, diese enthaltende antitumorzusammensetzungen und verfahren zu ihrer herstellung. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US4927919A (de) |
| EP (1) | EP0219852B1 (de) |
| JP (1) | JPS62174096A (de) |
| AT (1) | ATE72447T1 (de) |
| CA (1) | CA1294614C (de) |
| DE (1) | DE3683822D1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0381114B1 (de) * | 1989-01-30 | 1994-09-28 | Ishihara Sangyo Kaisha, Ltd. | Exo-3'-4'-O-benzyliden-3"-demethylchartreusin und seine Salze |
| IN172911B (de) * | 1991-02-26 | 1994-01-01 | Hoechst India | |
| ZA923817B (en) * | 1991-05-30 | 1993-02-24 | Bristol Myers Squibb Co | Chemical modification of elsamicin a at the 3'and/or 4'oh groups |
| HU210499B (en) * | 1991-05-30 | 1995-04-28 | Bristol Myers Squibb Co | Process for preparing 6-o-alkylelsamicin a deriv.s and pharmaceutical compn.s contg. them |
| ZA923818B (en) * | 1991-05-30 | 1993-11-25 | Bristol Myers Squibb Co | Chemical modification of 2"-amino group in elsamicin A |
| ZA923815B (en) * | 1991-05-30 | 1993-02-24 | Bristol Myers Squibb Co | Preparation of 6-o-acylelsamicin a derivatives |
| US5237055A (en) * | 1991-05-30 | 1993-08-17 | Bristol-Myers Squibb Company | Chemical modification of 2"-amino group in elsamicin A |
| US5229371A (en) * | 1991-05-30 | 1993-07-20 | Bristol-Myers Squibb Company | Chemical modification of elsamicin A at the 3' and/or 4' OH groups |
| US5289858A (en) * | 1991-12-18 | 1994-03-01 | Abbott Laboratories | System for accommodating withdrawal of liquid from a bulk supply |
| EP2664610A1 (de) * | 2009-05-01 | 2013-11-20 | Idemitsu Kosan Co., Ltd | Verfahren zur Herstellung von alpha, beta-ungesättigter Carbonsäure-N, N-disubstituiertem Amid und Verfahren zur Herstellung von 3-Alkoxycarbonsäure-N, N-disubstituiertem Amid |
| WO2014019685A1 (en) * | 2012-07-30 | 2014-02-06 | Leibniz-Institut Für Naturstoff-Forschung Und Infektionsbiologie | Novel chartreusin analogues |
| CN117924216A (zh) * | 2024-01-12 | 2024-04-26 | 王叔和生物医药(武汉)有限公司 | 一种1-哌啶丙酸的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4518589A (en) * | 1983-10-03 | 1985-05-21 | Bristol-Myers Company | BBM-2478 Antibiotic complex |
| US4760136A (en) * | 1984-04-27 | 1988-07-26 | Ishihara Sangyo Kaisha, Ltd. | Chartreusin derivatives and salts thereof |
-
1986
- 1986-10-21 DE DE8686114562T patent/DE3683822D1/de not_active Expired - Fee Related
- 1986-10-21 EP EP86114562A patent/EP0219852B1/de not_active Expired - Lifetime
- 1986-10-21 AT AT86114562T patent/ATE72447T1/de not_active IP Right Cessation
- 1986-10-22 JP JP61251154A patent/JPS62174096A/ja active Pending
- 1986-10-22 CA CA000521101A patent/CA1294614C/en not_active Expired - Fee Related
- 1986-10-23 US US06/922,433 patent/US4927919A/en not_active Expired - Lifetime
-
1989
- 1989-10-27 US US07/427,370 patent/US5064945A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3683822D1 (de) | 1992-03-19 |
| JPS62174096A (ja) | 1987-07-30 |
| EP0219852A2 (de) | 1987-04-29 |
| US5064945A (en) | 1991-11-12 |
| US4927919A (en) | 1990-05-22 |
| EP0219852B1 (de) | 1992-02-05 |
| CA1294614C (en) | 1992-01-21 |
| EP0219852A3 (en) | 1987-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |