SU1537136A3 - Способ получени 3-амино-4- @ 2-[(2-гуанидинотиазол-4-ил)метилтио]этиламино @ -1,2,5-тиадиазола или его фармацевтически приемлемой кислотно-аддитивной соли - Google Patents

Способ получени 3-амино-4- @ 2-[(2-гуанидинотиазол-4-ил)метилтио]этиламино @ -1,2,5-тиадиазола или его фармацевтически приемлемой кислотно-аддитивной соли Download PDF

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Publication number
SU1537136A3
SU1537136A3 SU853906050A SU3906050A SU1537136A3 SU 1537136 A3 SU1537136 A3 SU 1537136A3 SU 853906050 A SU853906050 A SU 853906050A SU 3906050 A SU3906050 A SU 3906050A SU 1537136 A3 SU1537136 A3 SU 1537136A3
Authority
SU
USSR - Soviet Union
Prior art keywords
pharmaceutically acceptable
formula
acceptable acid
amino
thiadiazole
Prior art date
Application number
SU853906050A
Other languages
English (en)
Russian (ru)
Inventor
А.Элджери Альдо
Р.Креншо Ронни
Original Assignee
Бристоль-Мейерз Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бристоль-Мейерз Компани (Фирма) filed Critical Бристоль-Мейерз Компани (Фирма)
Application granted granted Critical
Publication of SU1537136A3 publication Critical patent/SU1537136A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SU853906050A 1984-06-22 1985-06-05 Способ получени 3-амино-4- @ 2-[(2-гуанидинотиазол-4-ил)метилтио]этиламино @ -1,2,5-тиадиазола или его фармацевтически приемлемой кислотно-аддитивной соли SU1537136A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/623,588 US4644006A (en) 1984-06-22 1984-06-22 Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity

Publications (1)

Publication Number Publication Date
SU1537136A3 true SU1537136A3 (ru) 1990-01-15

Family

ID=24498651

Family Applications (1)

Application Number Title Priority Date Filing Date
SU853906050A SU1537136A3 (ru) 1984-06-22 1985-06-05 Способ получени 3-амино-4- @ 2-[(2-гуанидинотиазол-4-ил)метилтио]этиламино @ -1,2,5-тиадиазола или его фармацевтически приемлемой кислотно-аддитивной соли

Country Status (33)

Country Link
US (1) US4644006A (fr)
JP (2) JPS6118775A (fr)
KR (1) KR900004321B1 (fr)
AR (1) AR240935A1 (fr)
AT (1) AT390790B (fr)
AU (2) AU580605B2 (fr)
BE (1) BE902724A (fr)
CA (2) CA1267412A (fr)
CH (1) CH665210A5 (fr)
CS (1) CS257276B2 (fr)
DD (1) DD240889A5 (fr)
DE (1) DE3522101A1 (fr)
DK (1) DK282885A (fr)
ES (2) ES8702902A1 (fr)
FI (1) FI852405L (fr)
FR (1) FR2566406B1 (fr)
GB (2) GB2161157B (fr)
GR (1) GR851514B (fr)
HU (1) HU193992B (fr)
IE (2) IE58261B1 (fr)
IL (1) IL75567A0 (fr)
IT (1) IT1190372B (fr)
LU (1) LU85969A1 (fr)
NL (1) NL8501766A (fr)
NO (1) NO161856C (fr)
NZ (1) NZ212403A (fr)
OA (1) OA08039A (fr)
PT (1) PT80684B (fr)
SE (1) SE464305B (fr)
SU (1) SU1537136A3 (fr)
YU (2) YU45725B (fr)
ZA (1) ZA854710B (fr)
ZW (1) ZW10385A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0535227A4 (en) * 1990-05-29 1993-08-18 Nippon Soda Co., Ltd. N-substituted heterocyclic amidine derivative
EP4196793A1 (fr) 2020-08-11 2023-06-21 Université de Strasbourg Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
DK160611C (da) * 1979-09-04 1991-09-16 Bristol Myers Squibb Co Analogifremgangsmaade til fremstilling af 3,4-disubstituerede 1,2,5-thiadiazol-1-oxider og -1,1-dioxider
DE3175201D1 (en) * 1980-04-30 1986-10-02 Merck & Co Inc Aminothiadiazoles as gastric secretion inhibitors
US4394508A (en) * 1980-06-07 1983-07-19 Bristol-Myers Company Chemical compounds
EP0045155B1 (fr) * 1980-07-30 1985-01-02 Imperial Chemical Industries Plc Dérivés de guanidine
EP0060730A3 (fr) * 1981-03-18 1982-12-08 Imperial Chemical Industries Plc Dérivés bicycliques
EP0065823A1 (fr) * 1981-05-13 1982-12-01 Imperial Chemical Industries Plc Dérivés hétérocycliques de guanidine, comme antagonistes de histamine H-2
US4528375A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4588826A (en) * 1982-03-29 1986-05-13 Bristol-Myers Company Ethanediimidamide intermediates
ZW7683A1 (en) * 1982-03-29 1984-01-04 Bristol Myers Co Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity
US4528378A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4528377A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4517366A (en) * 1982-03-29 1985-05-14 Bristol-Myers Company Intermediates for preparing 3,4-diamino-1,2,5-thiadiazoles
FI832519L (fi) * 1982-07-12 1984-01-13 Bristol Myers Co Farmaceutiska foerfaranden och sammansaettningar
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
JPS5978171A (ja) * 1982-10-26 1984-05-04 Ikeda Mohandou:Kk 複素環式化合物
US4440933A (en) * 1983-03-16 1984-04-03 Bristol-Myers Company Process for preparing 1,2,5-thiadiazoles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент GB № 2117769, кл. С 07 D 285/Ю, 1983. *

Also Published As

Publication number Publication date
NO852519L (no) 1985-12-23
IT1190372B (it) 1988-02-16
IE851557L (en) 1985-12-22
FR2566406A1 (fr) 1985-12-27
NL8501766A (nl) 1986-01-16
NO161856C (no) 1989-10-04
GB2192884A (en) 1988-01-27
JPS6118775A (ja) 1986-01-27
SE464305B (sv) 1991-04-08
GB2161157A (en) 1986-01-08
DK282885D0 (da) 1985-06-21
CS257276B2 (en) 1988-04-15
GB2161157B (en) 1988-08-10
OA08039A (fr) 1987-01-31
CA1267412A (fr) 1990-04-03
NO161856B (no) 1989-06-26
SE8503110L (sv) 1985-12-23
YU105185A (en) 1987-12-31
PT80684A (en) 1985-07-01
FI852405L (fi) 1985-12-23
IE57937B1 (en) 1993-05-19
HU193992B (en) 1987-12-28
NZ212403A (en) 1989-04-26
ES544409A0 (es) 1987-01-16
AU4392085A (en) 1986-01-02
YU45725B (sh) 1992-07-20
KR860000275A (ko) 1986-01-27
ZW10385A1 (en) 1986-02-05
GR851514B (fr) 1985-11-25
IL75567A0 (en) 1985-10-31
ES551506A0 (es) 1987-01-16
ATA185885A (de) 1989-12-15
ZA854710B (en) 1986-02-26
US4644006A (en) 1987-02-17
JPS61186369A (ja) 1986-08-20
IE58261B1 (en) 1993-08-25
DK282885A (da) 1985-12-23
AU2977589A (en) 1989-06-01
BE902724A (fr) 1985-12-23
CH665210A5 (de) 1988-04-29
AU614331B2 (en) 1991-08-29
CA1297875C (fr) 1992-03-24
SE8503110D0 (sv) 1985-06-20
IT8521217A0 (it) 1985-06-20
HUT42087A (en) 1987-06-29
ES8702881A1 (es) 1987-01-16
AT390790B (de) 1990-06-25
DE3522101A1 (de) 1986-01-02
FR2566406B1 (fr) 1988-01-29
GB8716149D0 (en) 1987-08-12
GB2192884B (en) 1988-08-10
AR240935A2 (es) 1991-03-27
CS424785A2 (en) 1987-09-17
YU102587A (en) 1988-02-29
DD240889A5 (de) 1986-11-19
FI852405A0 (fi) 1985-06-17
GB8515749D0 (en) 1985-07-24
PT80684B (en) 1987-05-08
AU580605B2 (en) 1989-01-19
LU85969A1 (fr) 1986-01-24
AR240935A1 (es) 1991-03-27
ES8702902A1 (es) 1987-01-16
KR900004321B1 (ko) 1990-06-22
YU45822B (sh) 1992-07-20

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