ATA185885A - Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols - Google Patents

Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols

Info

Publication number
ATA185885A
ATA185885A AT0185885A AT185885A ATA185885A AT A185885 A ATA185885 A AT A185885A AT 0185885 A AT0185885 A AT 0185885A AT 185885 A AT185885 A AT 185885A AT A185885 A ATA185885 A AT A185885A
Authority
AT
Austria
Prior art keywords
guanidinothiazol
methylth
thiadiazol
ethylamino
amino
Prior art date
Application number
AT0185885A
Other languages
English (en)
Other versions
AT390790B (de
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Priority to AT0179289A priority Critical patent/ATA179289A/de
Priority to AT0260889A priority patent/ATA260889A/de
Publication of ATA185885A publication Critical patent/ATA185885A/de
Application granted granted Critical
Publication of AT390790B publication Critical patent/AT390790B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT0185885A 1984-06-22 1985-06-21 Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols AT390790B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT0179289A ATA179289A (de) 1984-06-22 1989-07-25 Verfahren zur herstellung des neuen n-(2-((2guanidinothiazol-4-yl)methyl-thio)ethyl)ethandiimidamids
AT0260889A ATA260889A (de) 1984-06-22 1989-11-15 Verfahren zur herstellung des neuen n-(2-( (2-guanidinothiazol-4-yl)methylthio)-ethyl)- ethandiimidamids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/623,588 US4644006A (en) 1984-06-22 1984-06-22 Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity

Publications (2)

Publication Number Publication Date
ATA185885A true ATA185885A (de) 1989-12-15
AT390790B AT390790B (de) 1990-06-25

Family

ID=24498651

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0185885A AT390790B (de) 1984-06-22 1985-06-21 Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols

Country Status (33)

Country Link
US (1) US4644006A (de)
JP (2) JPS6118775A (de)
KR (1) KR900004321B1 (de)
AR (1) AR240935A1 (de)
AT (1) AT390790B (de)
AU (2) AU580605B2 (de)
BE (1) BE902724A (de)
CA (2) CA1267412A (de)
CH (1) CH665210A5 (de)
CS (1) CS257276B2 (de)
DD (1) DD240889A5 (de)
DE (1) DE3522101A1 (de)
DK (1) DK282885A (de)
ES (2) ES8702902A1 (de)
FI (1) FI852405L (de)
FR (1) FR2566406B1 (de)
GB (2) GB2161157B (de)
GR (1) GR851514B (de)
HU (1) HU193992B (de)
IE (2) IE57937B1 (de)
IL (1) IL75567A0 (de)
IT (1) IT1190372B (de)
LU (1) LU85969A1 (de)
NL (1) NL8501766A (de)
NO (1) NO161856C (de)
NZ (1) NZ212403A (de)
OA (1) OA08039A (de)
PT (1) PT80684B (de)
SE (1) SE464305B (de)
SU (1) SU1537136A3 (de)
YU (2) YU45725B (de)
ZA (1) ZA854710B (de)
ZW (1) ZW10385A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0535227A4 (en) * 1990-05-29 1993-08-18 Nippon Soda Co., Ltd. N-substituted heterocyclic amidine derivative
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
FI76795C (fi) * 1979-09-04 1988-12-12 Bristol Myers Co Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara 3,4-disubstituerade 1,2,5-tiadiazol-1-oxider och -1,1-dioxider samt nya mellanprodukter.
DE3175201D1 (en) * 1980-04-30 1986-10-02 Merck & Co Inc Aminothiadiazoles as gastric secretion inhibitors
US4394508A (en) * 1980-06-07 1983-07-19 Bristol-Myers Company Chemical compounds
EP0045155B1 (de) * 1980-07-30 1985-01-02 Imperial Chemical Industries Plc Guanidinderivate
EP0060730A3 (de) * 1981-03-18 1982-12-08 Imperial Chemical Industries Plc Bicyclische Derivate
EP0065823A1 (de) * 1981-05-13 1982-12-01 Imperial Chemical Industries Plc Heterozyklische Guanidinderivate als Histamin-H-2-Antagonisten
US4528378A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4588826A (en) * 1982-03-29 1986-05-13 Bristol-Myers Company Ethanediimidamide intermediates
US4517366A (en) * 1982-03-29 1985-05-14 Bristol-Myers Company Intermediates for preparing 3,4-diamino-1,2,5-thiadiazoles
US4528377A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
ES8404683A1 (es) * 1982-03-29 1984-05-16 Bristol Myers Co Un procedimiento para la preparacion de antagonistas de los receptores hidrogeno de la histamina.
US4528375A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
FI832519L (fi) * 1982-07-12 1984-01-13 Bristol Myers Co Farmaceutiska foerfaranden och sammansaettningar
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
JPS5978171A (ja) * 1982-10-26 1984-05-04 Ikeda Mohandou:Kk 複素環式化合物
US4440933A (en) * 1983-03-16 1984-04-03 Bristol-Myers Company Process for preparing 1,2,5-thiadiazoles

Also Published As

Publication number Publication date
FI852405L (fi) 1985-12-23
DD240889A5 (de) 1986-11-19
BE902724A (fr) 1985-12-23
IE58261B1 (en) 1993-08-25
AU4392085A (en) 1986-01-02
AU580605B2 (en) 1989-01-19
ZA854710B (en) 1986-02-26
YU105185A (en) 1987-12-31
AT390790B (de) 1990-06-25
AR240935A1 (es) 1991-03-27
FR2566406A1 (fr) 1985-12-27
CH665210A5 (de) 1988-04-29
CA1267412A (en) 1990-04-03
IE57937B1 (en) 1993-05-19
JPS61186369A (ja) 1986-08-20
GB2161157A (en) 1986-01-08
GB8716149D0 (en) 1987-08-12
KR900004321B1 (ko) 1990-06-22
GB2161157B (en) 1988-08-10
NO161856B (no) 1989-06-26
PT80684A (en) 1985-07-01
FR2566406B1 (fr) 1988-01-29
KR860000275A (ko) 1986-01-27
SE8503110D0 (sv) 1985-06-20
CS257276B2 (en) 1988-04-15
CS424785A2 (en) 1987-09-17
AU614331B2 (en) 1991-08-29
CA1297875C (en) 1992-03-24
HU193992B (en) 1987-12-28
YU45822B (sh) 1992-07-20
ES8702902A1 (es) 1987-01-16
YU45725B (sh) 1992-07-20
HUT42087A (en) 1987-06-29
IT8521217A0 (it) 1985-06-20
IT1190372B (it) 1988-02-16
NZ212403A (en) 1989-04-26
OA08039A (fr) 1987-01-31
JPS6118775A (ja) 1986-01-27
GB8515749D0 (en) 1985-07-24
LU85969A1 (fr) 1986-01-24
ES8702881A1 (es) 1987-01-16
DE3522101A1 (de) 1986-01-02
ZW10385A1 (en) 1986-02-05
ES551506A0 (es) 1987-01-16
GB2192884A (en) 1988-01-27
IE851557L (en) 1985-12-22
DK282885A (da) 1985-12-23
ES544409A0 (es) 1987-01-16
AU2977589A (en) 1989-06-01
SU1537136A3 (ru) 1990-01-15
DK282885D0 (da) 1985-06-21
US4644006A (en) 1987-02-17
YU102587A (en) 1988-02-29
SE8503110L (sv) 1985-12-23
NO852519L (no) 1985-12-23
GR851514B (de) 1985-11-25
IL75567A0 (en) 1985-10-31
FI852405A0 (fi) 1985-06-17
NL8501766A (nl) 1986-01-16
NO161856C (no) 1989-10-04
GB2192884B (en) 1988-08-10
AR240935A2 (es) 1991-03-27
PT80684B (en) 1987-05-08
SE464305B (sv) 1991-04-08

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee