SU1470177A3 - Способ получени производных 2-ацилоксипропиламина или их фармакологически переносимых солей - Google Patents

Способ получени производных 2-ацилоксипропиламина или их фармакологически переносимых солей Download PDF

Info

Publication number
SU1470177A3
SU1470177A3 SU874202997A SU4202997A SU1470177A3 SU 1470177 A3 SU1470177 A3 SU 1470177A3 SU 874202997 A SU874202997 A SU 874202997A SU 4202997 A SU4202997 A SU 4202997A SU 1470177 A3 SU1470177 A3 SU 1470177A3
Authority
SU
USSR - Soviet Union
Prior art keywords
formula
compound
hydrogen
acyloxypropylamine
alkyl
Prior art date
Application number
SU874202997A
Other languages
English (en)
Russian (ru)
Inventor
Тростманн Уве
Шехтеле Кристоф
Маннхардт Карл
Рудольф Клаус
Марме Дитер
Original Assignee
Гедеке Аг (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гедеке Аг (Фирма) filed Critical Гедеке Аг (Фирма)
Application granted granted Critical
Publication of SU1470177A3 publication Critical patent/SU1470177A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Catalysts (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
  • Monitoring And Testing Of Nuclear Reactors (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measurement Of Force In General (AREA)
  • Breakers (AREA)
SU874202997A 1986-07-30 1987-07-24 Способ получени производных 2-ацилоксипропиламина или их фармакологически переносимых солей SU1470177A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863625738 DE3625738A1 (de) 1986-07-30 1986-07-30 2-acyloxypropylamin-derivate, verfahren zu deren herstellung und deren verwendung

Publications (1)

Publication Number Publication Date
SU1470177A3 true SU1470177A3 (ru) 1989-03-30

Family

ID=6306287

Family Applications (1)

Application Number Title Priority Date Filing Date
SU874202997A SU1470177A3 (ru) 1986-07-30 1987-07-24 Способ получени производных 2-ацилоксипропиламина или их фармакологически переносимых солей

Country Status (17)

Country Link
US (1) US4855489A (xx)
EP (1) EP0255126B1 (xx)
JP (1) JPS6348250A (xx)
KR (1) KR880001577A (xx)
AT (1) ATE81499T1 (xx)
AU (1) AU597090B2 (xx)
CA (1) CA1318670C (xx)
DD (1) DD266349A5 (xx)
DE (2) DE3625738A1 (xx)
DK (1) DK374887A (xx)
ES (1) ES2052525T3 (xx)
FI (1) FI89042C (xx)
GR (1) GR3006081T3 (xx)
HU (1) HU197720B (xx)
IL (1) IL83368A (xx)
SU (1) SU1470177A3 (xx)
ZA (1) ZA875640B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705384A1 (de) * 1987-02-20 1988-09-01 Goedecke Ag 2-propylamin-derivate, verfahren zu deren herstellung sowie deren verwendung
ES2038244T3 (es) * 1987-06-25 1993-07-16 Hoechst Aktiengesellschaft Procedimiento para preparar un nuevo antibiotico, fumifungina, y su empleo como medicamento.
DE3836987A1 (de) * 1988-10-31 1990-05-23 Goedecke Ag 2-aminocarbonsaeuren und deren derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
DE4243321A1 (de) * 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
GB2321455A (en) 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
CA2393720C (en) * 2002-07-12 2010-09-14 Eli Lilly And Company Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
US7476656B2 (en) * 2004-11-09 2009-01-13 University Of Florida Research Foundation, Inc. Fluorescent affinity tag to enhance phosphoprotein detection and characterization
US8930331B2 (en) 2007-02-21 2015-01-06 Palantir Technologies Providing unique views of data based on changes or rules
US9092482B2 (en) 2013-03-14 2015-07-28 Palantir Technologies, Inc. Fair scheduling for mixed-query loads

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU66207A1 (xx) * 1972-09-29 1974-04-02
CH618958A5 (en) * 1975-07-01 1980-08-29 Ciba Geigy Ag Process for the preparation of novel secondary acyloxyamines
DE2820892A1 (de) * 1978-05-12 1979-11-22 Nattermann A & Cie Neue strukturanaloga von glyveriden und verfahren zu deren herstellung
GB2172284B (en) * 1985-03-12 1988-07-27 Ciba Geigy Ag Nitrogen-containing additives for non-aqueous functional fluids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент GB № 1336350, кл. С 07 С 93/187, 1973. (54)СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 2-АЦИЛОКСШ1РрШ1ЛАМИНА ИЛИ ИХ ФАРМА КОЛОГИЧЕСКИ ПЕРЕНОСИМЫХ СОЛЕЙ *

Also Published As

Publication number Publication date
FI89042B (fi) 1993-04-30
FI873313A0 (fi) 1987-07-29
KR880001577A (ko) 1988-04-25
EP0255126A3 (en) 1989-01-11
EP0255126A2 (de) 1988-02-03
DK374887A (da) 1988-01-31
AU597090B2 (en) 1990-05-24
AU7624887A (en) 1988-02-04
IL83368A0 (en) 1987-12-31
JPS6348250A (ja) 1988-02-29
DD266349A5 (de) 1989-03-29
HUT44228A (en) 1988-02-29
GR3006081T3 (xx) 1993-06-21
US4855489A (en) 1989-08-08
CA1318670C (en) 1993-06-01
ZA875640B (en) 1988-11-30
ATE81499T1 (de) 1992-10-15
IL83368A (en) 1991-05-12
FI89042C (fi) 1993-08-10
ES2052525T3 (es) 1994-07-16
DE3782207D1 (de) 1992-11-19
DE3625738A1 (de) 1988-02-11
FI873313A (fi) 1988-01-31
DK374887D0 (da) 1987-07-17
EP0255126B1 (de) 1992-10-14
HU197720B (en) 1989-05-29

Similar Documents

Publication Publication Date Title
FI91527B (fi) Foerfarande foer framstaellning av en terapeutiskt anvaendbar (S)-1-(3-dimetylaminopropyl)-1-(4'-fluorfenyl)-1,3-dihydrobensofuran-5-karbonitril
SU1128830A3 (ru) Способ получени производных аминоэтанола или их солей
US4329302A (en) Synthetic phosphoglycerides possessing platelet activating properties
SU1470177A3 (ru) Способ получени производных 2-ацилоксипропиламина или их фармакологически переносимых солей
US20200017502A1 (en) Methods and reagents for radiolabeling
FI117438B (fi) Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi
KR20140106750A (ko) Mogat-2 억제제로서 유용한 벤질 술폰아미드 유도체
CA2054544A1 (en) Process for the preparation of piperazine derivatives
FI65987C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
SU493958A3 (ru) Способ получени производных 1-фенокси3-аминопропан 2-ола
SU508176A3 (ru) Способ получени аминопроизводных бензофенона
US4143140A (en) Morpholine carboxamides and use thereof
US3758546A (en) Methoxy amine derivatives and process for preparing them
CN114436925B (zh) 间二苯酚醚类化合物及其制备方法与应用
RU2034828C1 (ru) Производные аралкиламинов в рацемической или оптически активной форме или их фармацевтически приемлемые соли и способ их получения
US4172150A (en) Cardiac stimulants
Rzeszotarski et al. Cardioselectivity of. beta.-adrenoceptor blocking agents. 1. 1-[(4-Hydroxyphenethyl) amino]-3-(aryloxy) propan-2-ols
SU722480A3 (ru) Способ получени -аминоалкоксициклоалканов или их солей
JP2000103788A (ja) 光学活性エピハロヒドリンの製造方法
RU1132505C (ru) ГИДРОХЛОРИДЫ ПРОИЗВОДНЫХ 5-ФЕНОКСИМЕТИЛ-1,2,4-ОКСАДИАЗОЛА, ОБЛАДАЮЩИЕ β И a -АДРЕНОЛИТИЧЕСКОЙ АКТИВНОСТЬЮ
US20080146645A1 (en) Process for Preparing Indolinone Phenylaminopropanol Derivatives
EP0130554B1 (en) Novel, physiologically active substance, process for production thereof and pharmaceutical composition containing the same
Kamioka et al. Synthesis of chiral polyazamacrocycles of variable ring size
SU436821A1 (ru) Способ получени акридинилпиразолонов
SU1726475A1 (ru) 1,12-Диаза-2,5,8,11,15-пентаоксациклогептадекан и способ его получени