SMT201400048B - Profarmaci carba-nucleosidici 1'-sostutuiti per iltrattamento antivirale - Google Patents
Profarmaci carba-nucleosidici 1'-sostutuiti per iltrattamento antiviraleInfo
- Publication number
- SMT201400048B SMT201400048B SM201400048T SM201400048T SMT201400048B SM T201400048 B SMT201400048 B SM T201400048B SM 201400048 T SM201400048 T SM 201400048T SM 201400048 T SM201400048 T SM 201400048T SM T201400048 B SMT201400048 B SM T201400048B
- Authority
- SM
- San Marino
- Prior art keywords
- antiviral treatment
- substituted beta
- nucleoside prodrugs
- nucleoside
- prodrugs
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000002777 nucleoside Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34959710P | 2010-05-28 | 2010-05-28 | |
US35335110P | 2010-06-10 | 2010-06-10 | |
US36604110P | 2010-07-20 | 2010-07-20 | |
PCT/US2011/038253 WO2011150288A1 (en) | 2010-05-28 | 2011-05-26 | 1'-substituted-carba-nucleoside prodrugs for antiviral treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
SMT201400048B true SMT201400048B (it) | 2014-05-07 |
Family
ID=45375840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SM201400048T SMT201400048B (it) | 2010-05-28 | 2014-04-11 | Profarmaci carba-nucleosidici 1'-sostutuiti per iltrattamento antivirale |
Country Status (18)
Country | Link |
---|---|
US (1) | US8415308B2 (sr) |
EP (1) | EP2576534B1 (sr) |
JP (4) | JP5837577B2 (sr) |
AR (1) | AR084389A1 (sr) |
CY (1) | CY1115479T1 (sr) |
DK (1) | DK2576534T3 (sr) |
ES (1) | ES2465265T3 (sr) |
HK (1) | HK1182387A1 (sr) |
HR (1) | HRP20140370T1 (sr) |
ME (1) | ME01882B (sr) |
PL (1) | PL2576534T3 (sr) |
PT (1) | PT2576534E (sr) |
RS (1) | RS53244B (sr) |
SI (1) | SI2576534T1 (sr) |
SM (1) | SMT201400048B (sr) |
TW (1) | TW201201815A (sr) |
UY (1) | UY33414A (sr) |
WO (1) | WO2011150288A1 (sr) |
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PE20160217A1 (es) * | 2009-09-21 | 2016-05-18 | Gilead Sciences Inc | Analogos de carba-nucleosidos sustituidos con 2'-fluoro antivirales |
TW201201815A (en) * | 2010-05-28 | 2012-01-16 | Gilead Sciences Inc | 1'-substituted-carba-nucleoside prodrugs for antiviral treatment |
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2011
- 2011-05-25 TW TW100118301A patent/TW201201815A/zh unknown
- 2011-05-26 RS RS20140150A patent/RS53244B/sr unknown
- 2011-05-26 PT PT117258384T patent/PT2576534E/pt unknown
- 2011-05-26 JP JP2013512264A patent/JP5837577B2/ja active Active
- 2011-05-26 WO PCT/US2011/038253 patent/WO2011150288A1/en active Application Filing
- 2011-05-26 US US13/117,060 patent/US8415308B2/en active Active
- 2011-05-26 EP EP11725838.4A patent/EP2576534B1/en active Active
- 2011-05-26 PL PL11725838T patent/PL2576534T3/pl unknown
- 2011-05-26 ES ES11725838.4T patent/ES2465265T3/es active Active
- 2011-05-26 ME MEP-2014-58A patent/ME01882B/me unknown
- 2011-05-26 SI SI201130154T patent/SI2576534T1/sl unknown
- 2011-05-26 DK DK11725838.4T patent/DK2576534T3/da active
- 2011-05-27 UY UY0001033414A patent/UY33414A/es active IP Right Grant
- 2011-05-27 AR ARP110101821A patent/AR084389A1/es not_active Application Discontinuation
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2013
- 2013-08-20 HK HK13109734.7A patent/HK1182387A1/xx unknown
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2014
- 2014-04-02 CY CY20141100249T patent/CY1115479T1/el unknown
- 2014-04-11 SM SM201400048T patent/SMT201400048B/xx unknown
- 2014-04-22 HR HRP20140370AT patent/HRP20140370T1/hr unknown
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2015
- 2015-11-05 JP JP2015217492A patent/JP6193332B2/ja active Active
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2017
- 2017-08-09 JP JP2017154096A patent/JP2018012706A/ja active Pending
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2018
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Also Published As
Publication number | Publication date |
---|---|
TW201201815A (en) | 2012-01-16 |
JP2013528184A (ja) | 2013-07-08 |
US8415308B2 (en) | 2013-04-09 |
JP2016094404A (ja) | 2016-05-26 |
RS53244B (sr) | 2014-08-29 |
DK2576534T3 (da) | 2014-04-22 |
EP2576534A1 (en) | 2013-04-10 |
JP2018012706A (ja) | 2018-01-25 |
EP2576534B1 (en) | 2014-03-19 |
PL2576534T3 (pl) | 2014-07-31 |
AR084389A1 (es) | 2013-05-15 |
HK1182387A1 (en) | 2013-11-29 |
PT2576534E (pt) | 2014-05-29 |
US20120020921A1 (en) | 2012-01-26 |
HRP20140370T1 (hr) | 2014-05-23 |
UY33414A (es) | 2011-12-30 |
JP6193332B2 (ja) | 2017-09-06 |
JP2018162268A (ja) | 2018-10-18 |
ES2465265T3 (es) | 2014-06-05 |
ME01882B (me) | 2014-12-20 |
WO2011150288A1 (en) | 2011-12-01 |
CY1115479T1 (el) | 2017-01-04 |
JP5837577B2 (ja) | 2015-12-24 |
SI2576534T1 (sl) | 2014-06-30 |
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