SK96494A3 - Piperazine and piperidine derivatives, and their use as antipsychotic - Google Patents
Piperazine and piperidine derivatives, and their use as antipsychotic Download PDFInfo
- Publication number
- SK96494A3 SK96494A3 SK964-94A SK96494A SK96494A3 SK 96494 A3 SK96494 A3 SK 96494A3 SK 96494 A SK96494 A SK 96494A SK 96494 A3 SK96494 A3 SK 96494A3
- Authority
- SK
- Slovakia
- Prior art keywords
- formula
- group
- compound
- piperazinyl
- butyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929202915A GB9202915D0 (en) | 1992-02-12 | 1992-02-12 | Chemical compounds |
| PCT/GB1993/000285 WO1993016073A1 (en) | 1992-02-12 | 1993-02-11 | Piperazine and piperidine derivatives, and their use as antipsychotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK96494A3 true SK96494A3 (en) | 1995-07-11 |
Family
ID=10710223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK964-94A SK96494A3 (en) | 1992-02-12 | 1993-02-11 | Piperazine and piperidine derivatives, and their use as antipsychotic |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0625978A1 (ko) |
| JP (1) | JPH07503723A (ko) |
| KR (1) | KR950700290A (ko) |
| AU (1) | AU3460393A (ko) |
| CA (1) | CA2117434A1 (ko) |
| CZ (1) | CZ194994A3 (ko) |
| FI (1) | FI943718A0 (ko) |
| GB (1) | GB9202915D0 (ko) |
| HU (1) | HUT72309A (ko) |
| IL (1) | IL104690A0 (ko) |
| MX (1) | MX9300786A (ko) |
| NO (1) | NO942977L (ko) |
| RU (1) | RU94038064A (ko) |
| SK (1) | SK96494A3 (ko) |
| WO (1) | WO1993016073A1 (ko) |
| ZA (1) | ZA93958B (ko) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| RU2118322C1 (ru) * | 1993-07-05 | 1998-08-27 | Дюфар Интернэшнл Рисерч Б.В. | 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли |
| US6001827A (en) | 1993-12-24 | 1999-12-14 | Suntory Limited | Benzothiazine derivative |
| JPH0912562A (ja) * | 1995-06-22 | 1997-01-14 | Suntory Ltd | 置換ベンゾチアジン誘導体 |
| CA2156849A1 (en) * | 1993-12-24 | 1995-07-06 | Akira Mizuno | Benzothiazine derivative |
| US5874429A (en) * | 1993-12-24 | 1999-02-23 | Suntory Limited | Benzothiazine derivative |
| WO1996014297A1 (fr) * | 1994-11-04 | 1996-05-17 | Sumitomo Pharmaceuticals Company, Limited | Nouveaux derives de lactame |
| DE69618050T2 (de) * | 1995-03-17 | 2002-07-11 | Aventis Pharmaceuticals Inc., Cincinnati | Substituierte Benzylthienylpiperazine, ihre Anwendung als Arzneimittel und Verfahren für ihre Herstellung |
| US6087364A (en) * | 1998-01-29 | 2000-07-11 | Warner-Lambert Company | Dopamine D4 receptor antagonists |
| DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| US7030142B1 (en) | 1999-04-06 | 2006-04-18 | Sepracor Inc. | Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites |
| JP2002541098A (ja) * | 1999-04-06 | 2002-12-03 | セプラコア インコーポレーテッド | ジプラシドン代謝産物を用いる神経弛緩薬性障害および関連障害を治療するための方法および組成物 |
| AR028685A1 (es) * | 2000-06-14 | 2003-05-21 | Lundbeck & Co As H | Derivados de indol |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| ES2326078T3 (es) | 2002-08-22 | 2009-09-30 | Dainippon Sumitomo Pharma Co., Ltd. | Medicamento destinado al sindrome de la disfuncion de integracion. |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| CN1826338B (zh) | 2003-06-23 | 2011-07-13 | 大日本住友制药株式会社 | 老年性痴呆症治疗药 |
| DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| US20070160537A1 (en) | 2004-02-20 | 2007-07-12 | Takeo Ishiyama | In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia |
| US20100041647A1 (en) * | 2007-01-03 | 2010-02-18 | Cortex Pharmaceuticals, Inc. | 3-Substituted-[1,2,3]-Benzotriazinone compounds for enhancing glutamatergic synaptic responses |
| US8258139B2 (en) | 2010-11-08 | 2012-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Method of treatment for mental disorders |
| GB201102248D0 (en) | 2011-02-09 | 2011-03-23 | Isis Innovation | Treatment of bipolar disorder |
| WO2013014665A1 (en) * | 2011-07-28 | 2013-01-31 | Mapi Pharma Ltd. | Intermediate compounds and process for the preparation of lurasidone and salts thereof |
| EP3027598B1 (en) * | 2013-07-31 | 2017-04-12 | Merck Patent GmbH | Oxoquinazolinyl-butanamide derivatives |
| CN105669665A (zh) * | 2016-03-15 | 2016-06-15 | 烟台贝森医药科技有限公司 | 哌罗匹隆的制备方法 |
| US11246905B2 (en) | 2016-08-15 | 2022-02-15 | President And Fellows Of Harvard College | Treating infections using IdsD from Proteus mirabilis |
| CN115124464B (zh) * | 2022-07-04 | 2023-06-06 | 新乡学院 | 一种喹啉二酮磺酰哌嗪杂合体及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2258843B1 (ko) * | 1974-01-30 | 1977-09-09 | Roussel Uclaf | |
| US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
| JPH0625181B2 (ja) * | 1985-03-27 | 1994-04-06 | 住友製薬株式会社 | 新規なイミド誘導体 |
| JP2660407B2 (ja) * | 1986-09-26 | 1997-10-08 | 住友製薬株式会社 | 新規なイミド誘導体 |
| CA1335289C (en) * | 1987-10-26 | 1995-04-18 | Fujio Antoku | Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use |
| US5001130A (en) * | 1988-02-18 | 1991-03-19 | Bristol-Myers Company | Psychotropic heterobicycloalkylpiperazine derivatives |
| US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
| NZ230045A (en) * | 1988-08-05 | 1990-11-27 | Janssen Pharmaceutica Nv | 3-piperazinylbenzazole derivatives and pharmaceutical compositions |
| US4968792A (en) * | 1989-09-25 | 1990-11-06 | American Home Products Corporation | Psychotropic benzisothiazole derivatives |
| JP2800953B2 (ja) * | 1990-07-06 | 1998-09-21 | 住友製薬株式会社 | 新規なイミド誘導体 |
-
1992
- 1992-02-12 GB GB929202915A patent/GB9202915D0/en active Pending
-
1993
- 1993-02-11 AU AU34603/93A patent/AU3460393A/en not_active Abandoned
- 1993-02-11 EP EP93903266A patent/EP0625978A1/en not_active Withdrawn
- 1993-02-11 WO PCT/GB1993/000285 patent/WO1993016073A1/en not_active Application Discontinuation
- 1993-02-11 CA CA002117434A patent/CA2117434A1/en not_active Abandoned
- 1993-02-11 JP JP5513907A patent/JPH07503723A/ja active Pending
- 1993-02-11 ZA ZA93958A patent/ZA93958B/xx unknown
- 1993-02-11 RU RU94038064/04A patent/RU94038064A/ru unknown
- 1993-02-11 CZ CZ941949A patent/CZ194994A3/cs unknown
- 1993-02-11 SK SK964-94A patent/SK96494A3/sk unknown
- 1993-02-11 HU HU9402343A patent/HUT72309A/hu unknown
- 1993-02-11 IL IL104690A patent/IL104690A0/xx unknown
- 1993-02-12 MX MX9300786A patent/MX9300786A/es unknown
-
1994
- 1994-08-11 FI FI943718A patent/FI943718A0/fi unknown
- 1994-08-11 NO NO942977A patent/NO942977L/no unknown
- 1994-08-12 KR KR1019940702790A patent/KR950700290A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07503723A (ja) | 1995-04-20 |
| NO942977D0 (no) | 1994-08-11 |
| EP0625978A1 (en) | 1994-11-30 |
| MX9300786A (es) | 1994-03-31 |
| AU3460393A (en) | 1993-09-03 |
| ZA93958B (en) | 1994-08-11 |
| HU9402343D0 (en) | 1994-10-28 |
| WO1993016073A1 (en) | 1993-08-19 |
| KR950700290A (ko) | 1995-01-16 |
| CZ194994A3 (en) | 1995-09-13 |
| NO942977L (no) | 1994-10-10 |
| FI943718A (fi) | 1994-08-11 |
| CA2117434A1 (en) | 1993-08-19 |
| IL104690A0 (en) | 1993-06-10 |
| HUT72309A (en) | 1996-04-29 |
| GB9202915D0 (en) | 1992-03-25 |
| RU94038064A (ru) | 1997-05-27 |
| FI943718A0 (fi) | 1994-08-11 |
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