KR950700290A - 피페라진 및 피레리딘 유도체, 및 이들의 항정신병제로서의 용도(piperazine and piperidine derivatives, and their use as antipsychotics) - Google Patents
피페라진 및 피레리딘 유도체, 및 이들의 항정신병제로서의 용도(piperazine and piperidine derivatives, and their use as antipsychotics)Info
- Publication number
- KR950700290A KR950700290A KR1019940702790A KR19940702790A KR950700290A KR 950700290 A KR950700290 A KR 950700290A KR 1019940702790 A KR1019940702790 A KR 1019940702790A KR 19940702790 A KR19940702790 A KR 19940702790A KR 950700290 A KR950700290 A KR 950700290A
- Authority
- KR
- South Korea
- Prior art keywords
- antipsychotics
- piperazine
- derivatives
- piperidine
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929202915A GB9202915D0 (en) | 1992-02-12 | 1992-02-12 | Chemical compounds |
| PCT/GB1993/000285 WO1993016073A1 (en) | 1992-02-12 | 1993-02-11 | Piperazine and piperidine derivatives, and their use as antipsychotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR950700290A true KR950700290A (ko) | 1995-01-16 |
Family
ID=10710223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019940702790A KR950700290A (ko) | 1992-02-12 | 1994-08-12 | 피페라진 및 피레리딘 유도체, 및 이들의 항정신병제로서의 용도(piperazine and piperidine derivatives, and their use as antipsychotics) |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0625978A1 (ko) |
| JP (1) | JPH07503723A (ko) |
| KR (1) | KR950700290A (ko) |
| AU (1) | AU3460393A (ko) |
| CA (1) | CA2117434A1 (ko) |
| CZ (1) | CZ194994A3 (ko) |
| FI (1) | FI943718A0 (ko) |
| GB (1) | GB9202915D0 (ko) |
| HU (1) | HUT72309A (ko) |
| IL (1) | IL104690A0 (ko) |
| MX (1) | MX9300786A (ko) |
| NO (1) | NO942977L (ko) |
| RU (1) | RU94038064A (ko) |
| SK (1) | SK96494A3 (ko) |
| WO (1) | WO1993016073A1 (ko) |
| ZA (1) | ZA93958B (ko) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| US5364866A (en) | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| RU2118322C1 (ru) * | 1993-07-05 | 1998-08-27 | Дюфар Интернэшнл Рисерч Б.В. | 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли |
| CN1058492C (zh) * | 1993-12-24 | 2000-11-15 | 三得利株式会社 | 苯并噻嗪衍生物 |
| JPH0912562A (ja) * | 1995-06-22 | 1997-01-14 | Suntory Ltd | 置換ベンゾチアジン誘導体 |
| US5874429A (en) * | 1993-12-24 | 1999-02-23 | Suntory Limited | Benzothiazine derivative |
| US6001827A (en) | 1993-12-24 | 1999-12-14 | Suntory Limited | Benzothiazine derivative |
| JP3948744B2 (ja) * | 1994-11-04 | 2007-07-25 | 大日本住友製薬株式会社 | 新規なラクタム誘導体 |
| EP0732332B1 (en) * | 1995-03-17 | 2001-12-19 | Aventis Pharmaceuticals Inc. | Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation |
| US6087364A (en) * | 1998-01-29 | 2000-07-11 | Warner-Lambert Company | Dopamine D4 receptor antagonists |
| DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| US7030142B1 (en) | 1999-04-06 | 2006-04-18 | Sepracor Inc. | Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites |
| EP1165083A2 (en) * | 1999-04-06 | 2002-01-02 | Sepracor Inc. | Methods and compositions for the treatment of psychotic and related disorders using ziprasidone metabolites |
| AR028685A1 (es) | 2000-06-14 | 2003-05-21 | Lundbeck & Co As H | Derivados de indol |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| DE60327634D1 (de) | 2002-08-22 | 2009-06-25 | Dainippon Sumitomo Pharma Co | Mittel zur behandlung des integrationsdysfunktionssyndroms |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| EP1637530A4 (en) * | 2003-06-23 | 2009-04-01 | Dainippon Sumitomo Pharma Co | THERAPEUTIC AGENT FOR SENILE DEMENTIA |
| DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| JP4847320B2 (ja) | 2004-02-20 | 2011-12-28 | 大日本住友製薬株式会社 | 統合失調症の記憶・学習機能障害治療薬のｉｎｖｉｖｏスクリーニング方法 |
| EA200900937A1 (ru) * | 2007-01-03 | 2009-12-30 | Кортекс Фармасеутикалс, Инк. | Соединения 3-замещенного-[1,2,3]бензотриазинона для усиления глутаматергических синаптических ответов |
| US8258139B2 (en) | 2010-11-08 | 2012-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Method of treatment for mental disorders |
| GB201102248D0 (en) | 2011-02-09 | 2011-03-23 | Isis Innovation | Treatment of bipolar disorder |
| WO2013014665A1 (en) * | 2011-07-28 | 2013-01-31 | Mapi Pharma Ltd. | Intermediate compounds and process for the preparation of lurasidone and salts thereof |
| US9901577B2 (en) * | 2013-07-31 | 2018-02-27 | Merck Patent Gmbh | Oxoquinazolinyl-butanamide derivatives |
| CN105669665A (zh) * | 2016-03-15 | 2016-06-15 | 烟台贝森医药科技有限公司 | 哌罗匹隆的制备方法 |
| US11246905B2 (en) | 2016-08-15 | 2022-02-15 | President And Fellows Of Harvard College | Treating infections using IdsD from Proteus mirabilis |
| CN115124464B (zh) * | 2022-07-04 | 2023-06-06 | 新乡学院 | 一种喹啉二酮磺酰哌嗪杂合体及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2258843B1 (ko) * | 1974-01-30 | 1977-09-09 | Roussel Uclaf | |
| US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
| JPH0625181B2 (ja) * | 1985-03-27 | 1994-04-06 | 住友製薬株式会社 | 新規なイミド誘導体 |
| AU593194B2 (en) * | 1986-09-26 | 1990-02-01 | Sumitomo Pharmaceuticals Company, Limited | Imide derivatives ,and their production and use |
| CA1335289C (en) * | 1987-10-26 | 1995-04-18 | Fujio Antoku | Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use |
| US5001130A (en) * | 1988-02-18 | 1991-03-19 | Bristol-Myers Company | Psychotropic heterobicycloalkylpiperazine derivatives |
| US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
| NZ230045A (en) * | 1988-08-05 | 1990-11-27 | Janssen Pharmaceutica Nv | 3-piperazinylbenzazole derivatives and pharmaceutical compositions |
| US4968792A (en) * | 1989-09-25 | 1990-11-06 | American Home Products Corporation | Psychotropic benzisothiazole derivatives |
| JP2800953B2 (ja) * | 1990-07-06 | 1998-09-21 | 住友製薬株式会社 | 新規なイミド誘導体 |
-
1992
- 1992-02-12 GB GB929202915A patent/GB9202915D0/en active Pending
-
1993
- 1993-02-11 AU AU34603/93A patent/AU3460393A/en not_active Abandoned
- 1993-02-11 HU HU9402343A patent/HUT72309A/hu unknown
- 1993-02-11 IL IL104690A patent/IL104690A0/xx unknown
- 1993-02-11 CZ CZ941949A patent/CZ194994A3/cs unknown
- 1993-02-11 RU RU94038064/04A patent/RU94038064A/ru unknown
- 1993-02-11 JP JP5513907A patent/JPH07503723A/ja active Pending
- 1993-02-11 CA CA002117434A patent/CA2117434A1/en not_active Abandoned
- 1993-02-11 WO PCT/GB1993/000285 patent/WO1993016073A1/en not_active Application Discontinuation
- 1993-02-11 SK SK964-94A patent/SK96494A3/sk unknown
- 1993-02-11 EP EP93903266A patent/EP0625978A1/en not_active Withdrawn
- 1993-02-11 ZA ZA93958A patent/ZA93958B/xx unknown
- 1993-02-12 MX MX9300786A patent/MX9300786A/es unknown
-
1994
- 1994-08-11 FI FI943718A patent/FI943718A0/fi unknown
- 1994-08-11 NO NO942977A patent/NO942977L/no unknown
- 1994-08-12 KR KR1019940702790A patent/KR950700290A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI943718A (fi) | 1994-08-11 |
| CA2117434A1 (en) | 1993-08-19 |
| JPH07503723A (ja) | 1995-04-20 |
| FI943718A0 (fi) | 1994-08-11 |
| NO942977D0 (no) | 1994-08-11 |
| CZ194994A3 (en) | 1995-09-13 |
| MX9300786A (es) | 1994-03-31 |
| HU9402343D0 (en) | 1994-10-28 |
| GB9202915D0 (en) | 1992-03-25 |
| ZA93958B (en) | 1994-08-11 |
| IL104690A0 (en) | 1993-06-10 |
| WO1993016073A1 (en) | 1993-08-19 |
| AU3460393A (en) | 1993-09-03 |
| HUT72309A (en) | 1996-04-29 |
| RU94038064A (ru) | 1997-05-27 |
| NO942977L (no) | 1994-10-10 |
| EP0625978A1 (en) | 1994-11-30 |
| SK96494A3 (en) | 1995-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |