FI943718A - Piperatsiini- ja piperadiinijohdannaisia ja niiden käyttö antipsykoottisina aineina - Google Patents
Piperatsiini- ja piperadiinijohdannaisia ja niiden käyttö antipsykoottisina aineina Download PDFInfo
- Publication number
- FI943718A FI943718A FI943718A FI943718A FI943718A FI 943718 A FI943718 A FI 943718A FI 943718 A FI943718 A FI 943718A FI 943718 A FI943718 A FI 943718A FI 943718 A FI943718 A FI 943718A
- Authority
- FI
- Finland
- Prior art keywords
- antipsychotics
- piperazine
- piperadine
- derivatives
- piperadine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929202915A GB9202915D0 (en) | 1992-02-12 | 1992-02-12 | Chemical compounds |
PCT/GB1993/000285 WO1993016073A1 (en) | 1992-02-12 | 1993-02-11 | Piperazine and piperidine derivatives, and their use as antipsychotics |
Publications (2)
Publication Number | Publication Date |
---|---|
FI943718A true FI943718A (fi) | 1994-08-11 |
FI943718A0 FI943718A0 (fi) | 1994-08-11 |
Family
ID=10710223
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI943718A FI943718A0 (fi) | 1992-02-12 | 1994-08-11 | Piperatsiini- ja piperadiinijohdannaisia ja niiden käyttö antipsykoottisina aineina |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0625978A1 (fi) |
JP (1) | JPH07503723A (fi) |
KR (1) | KR950700290A (fi) |
AU (1) | AU3460393A (fi) |
CA (1) | CA2117434A1 (fi) |
CZ (1) | CZ194994A3 (fi) |
FI (1) | FI943718A0 (fi) |
GB (1) | GB9202915D0 (fi) |
HU (1) | HUT72309A (fi) |
IL (1) | IL104690A0 (fi) |
MX (1) | MX9300786A (fi) |
NO (1) | NO942977L (fi) |
RU (1) | RU94038064A (fi) |
SK (1) | SK96494A3 (fi) |
WO (1) | WO1993016073A1 (fi) |
ZA (1) | ZA93958B (fi) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776963A (en) | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
US5364866A (en) | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
RU2118322C1 (ru) * | 1993-07-05 | 1998-08-27 | Дюфар Интернэшнл Рисерч Б.В. | 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли |
US5874429A (en) * | 1993-12-24 | 1999-02-23 | Suntory Limited | Benzothiazine derivative |
WO1995018117A1 (fr) * | 1993-12-24 | 1995-07-06 | Suntory Limited | Derive de benzothiazine |
JPH0912562A (ja) * | 1995-06-22 | 1997-01-14 | Suntory Ltd | 置換ベンゾチアジン誘導体 |
US6001827A (en) * | 1993-12-24 | 1999-12-14 | Suntory Limited | Benzothiazine derivative |
JP3948744B2 (ja) * | 1994-11-04 | 2007-07-25 | 大日本住友製薬株式会社 | 新規なラクタム誘導体 |
DK0732332T3 (da) * | 1995-03-17 | 2002-04-15 | Aventis Pharma Inc | Substituerede benzothienylpiperaziner, deres anvendelse som lægemidler og fremgangsmåder til fremstilling deraf |
US6087364A (en) * | 1998-01-29 | 2000-07-11 | Warner-Lambert Company | Dopamine D4 receptor antagonists |
DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
WO2000059489A2 (en) * | 1999-04-06 | 2000-10-12 | Sepracor Inc. | Methods and compositions for the treatment of psychotic and related disorders using ziprasidone metabolites |
US7030142B1 (en) | 1999-04-06 | 2006-04-18 | Sepracor Inc. | Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites |
AR028685A1 (es) * | 2000-06-14 | 2003-05-21 | Lundbeck & Co As H | Derivados de indol |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
EP2295061A1 (en) | 2002-08-22 | 2011-03-16 | Dainippon Sumitomo Pharma Co., Ltd. | Agent for treatment of schizophrenia |
DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
WO2004113333A1 (ja) * | 2003-06-23 | 2004-12-29 | Dainippon Sumitomo Pharma Co., Ltd. | 老人性痴呆症治療剤 |
DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
EP2357474A1 (en) | 2004-02-20 | 2011-08-17 | Dainippon Sumitomo Pharma Co., Ltd. | Lurasidone for use in the treatment of memory or learning dysfunction by schizophrenia |
MX2009007209A (es) * | 2007-01-03 | 2009-10-12 | Cortex Pharma Inc | Compuestos de [1, 2, 3]-benzotriazinona-sustituidos en la posicion 3 para mejorar las respuestas sinapticas glutamatergicas. |
US8258139B2 (en) | 2010-11-08 | 2012-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Method of treatment for mental disorders |
GB201102248D0 (en) | 2011-02-09 | 2011-03-23 | Isis Innovation | Treatment of bipolar disorder |
US8981095B2 (en) | 2011-07-28 | 2015-03-17 | Mapi Pharma Ltd. | Intermediate compounds and process for the preparation of lurasidone and salts thereof |
PT3027598T (pt) * | 2013-07-31 | 2017-07-17 | Merck Patent Gmbh | Derivados de oxoquinazolinil-butanamida |
CN105669665A (zh) * | 2016-03-15 | 2016-06-15 | 烟台贝森医药科技有限公司 | 哌罗匹隆的制备方法 |
WO2018035046A1 (en) | 2016-08-15 | 2018-02-22 | President And Fellows Of Harvard College | Treating infections using idsd from proteus mirabilis |
CN115124464B (zh) * | 2022-07-04 | 2023-06-06 | 新乡学院 | 一种喹啉二酮磺酰哌嗪杂合体及其制备方法和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2258843B1 (fi) * | 1974-01-30 | 1977-09-09 | Roussel Uclaf | |
US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
JPH0625181B2 (ja) * | 1985-03-27 | 1994-04-06 | 住友製薬株式会社 | 新規なイミド誘導体 |
JP2660407B2 (ja) * | 1986-09-26 | 1997-10-08 | 住友製薬株式会社 | 新規なイミド誘導体 |
CA1335289C (en) * | 1987-10-26 | 1995-04-18 | Fujio Antoku | Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use |
US5001130A (en) * | 1988-02-18 | 1991-03-19 | Bristol-Myers Company | Psychotropic heterobicycloalkylpiperazine derivatives |
US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
NZ230045A (en) * | 1988-08-05 | 1990-11-27 | Janssen Pharmaceutica Nv | 3-piperazinylbenzazole derivatives and pharmaceutical compositions |
US4968792A (en) * | 1989-09-25 | 1990-11-06 | American Home Products Corporation | Psychotropic benzisothiazole derivatives |
JP2800953B2 (ja) * | 1990-07-06 | 1998-09-21 | 住友製薬株式会社 | 新規なイミド誘導体 |
-
1992
- 1992-02-12 GB GB929202915A patent/GB9202915D0/en active Pending
-
1993
- 1993-02-11 AU AU34603/93A patent/AU3460393A/en not_active Abandoned
- 1993-02-11 IL IL104690A patent/IL104690A0/xx unknown
- 1993-02-11 SK SK964-94A patent/SK96494A3/sk unknown
- 1993-02-11 EP EP93903266A patent/EP0625978A1/en not_active Withdrawn
- 1993-02-11 JP JP5513907A patent/JPH07503723A/ja active Pending
- 1993-02-11 CZ CZ941949A patent/CZ194994A3/cs unknown
- 1993-02-11 CA CA002117434A patent/CA2117434A1/en not_active Abandoned
- 1993-02-11 ZA ZA93958A patent/ZA93958B/xx unknown
- 1993-02-11 WO PCT/GB1993/000285 patent/WO1993016073A1/en not_active Application Discontinuation
- 1993-02-11 HU HU9402343A patent/HUT72309A/hu unknown
- 1993-02-11 RU RU94038064/04A patent/RU94038064A/ru unknown
- 1993-02-12 MX MX9300786A patent/MX9300786A/es unknown
-
1994
- 1994-08-11 FI FI943718A patent/FI943718A0/fi unknown
- 1994-08-11 NO NO942977A patent/NO942977L/no unknown
- 1994-08-12 KR KR1019940702790A patent/KR950700290A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL104690A0 (en) | 1993-06-10 |
MX9300786A (es) | 1994-03-31 |
EP0625978A1 (en) | 1994-11-30 |
CZ194994A3 (en) | 1995-09-13 |
CA2117434A1 (en) | 1993-08-19 |
GB9202915D0 (en) | 1992-03-25 |
KR950700290A (ko) | 1995-01-16 |
ZA93958B (en) | 1994-08-11 |
SK96494A3 (en) | 1995-07-11 |
HUT72309A (en) | 1996-04-29 |
FI943718A0 (fi) | 1994-08-11 |
HU9402343D0 (en) | 1994-10-28 |
RU94038064A (ru) | 1997-05-27 |
NO942977L (no) | 1994-10-10 |
AU3460393A (en) | 1993-09-03 |
JPH07503723A (ja) | 1995-04-20 |
WO1993016073A1 (en) | 1993-08-19 |
NO942977D0 (no) | 1994-08-11 |
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