SK76396A3 - Cyclic amide derivatives, preparation method thereof and pharmaceutical compositions containing them - Google Patents

Cyclic amide derivatives, preparation method thereof and pharmaceutical compositions containing them Download PDF

Info

Publication number
SK76396A3
SK76396A3 SK763-96A SK76396A SK76396A3 SK 76396 A3 SK76396 A3 SK 76396A3 SK 76396 A SK76396 A SK 76396A SK 76396 A3 SK76396 A3 SK 76396A3
Authority
SK
Slovakia
Prior art keywords
dichlorophenyl
group
methyl
nitrogen atom
piperidino
Prior art date
Application number
SK763-96A
Other languages
English (en)
Slovak (sk)
Inventor
Asbokkumar B Shenvi
Robert T Jacobs
Scott C Miller
Cyrus J Ohnmacht Jr
Chris A Veale
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939325654A external-priority patent/GB9325654D0/en
Priority claimed from GB9423248A external-priority patent/GB9423248D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of SK76396A3 publication Critical patent/SK76396A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SK763-96A 1993-12-15 1994-12-13 Cyclic amide derivatives, preparation method thereof and pharmaceutical compositions containing them SK76396A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939325654A GB9325654D0 (en) 1993-12-15 1993-12-15 Cyclic amide derivatives
GB9423248A GB9423248D0 (en) 1994-11-17 1994-11-17 Cyclic amide derivatives
PCT/GB1994/002726 WO1995016682A1 (en) 1993-12-15 1994-12-13 Cyclic amide derivatives as neurokinin a antagonists

Publications (1)

Publication Number Publication Date
SK76396A3 true SK76396A3 (en) 1996-12-04

Family

ID=26304034

Family Applications (1)

Application Number Title Priority Date Filing Date
SK763-96A SK76396A3 (en) 1993-12-15 1994-12-13 Cyclic amide derivatives, preparation method thereof and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (3) US5589489A (fi)
EP (1) EP0734383B1 (fi)
JP (1) JP3819934B2 (fi)
CN (1) CN1142822A (fi)
AT (1) ATE221064T1 (fi)
AU (1) AU690951B2 (fi)
BR (1) BR9408325A (fi)
CA (1) CA2176036A1 (fi)
CZ (1) CZ171796A3 (fi)
DE (1) DE69431069T2 (fi)
DK (1) DK0734383T3 (fi)
ES (1) ES2179094T3 (fi)
FI (1) FI962418A (fi)
HU (1) HUT76275A (fi)
IL (1) IL111970A (fi)
NO (1) NO962543L (fi)
NZ (1) NZ277291A (fi)
PL (1) PL315035A1 (fi)
PT (1) PT734383E (fi)
SG (1) SG52667A1 (fi)
SK (1) SK76396A3 (fi)
WO (1) WO1995016682A1 (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives
GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles
GB9408872D0 (en) * 1994-05-03 1994-06-22 Zeneca Ltd Heterocyclic compounds
EP0709375B1 (en) * 1994-10-25 2005-05-18 AstraZeneca AB Therapeutic heterocycles
US5998444A (en) * 1995-10-24 1999-12-07 Zeneca Ltd. Piperidinyl compounds as NK1 or NK2 antagonists
US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
GB9508786D0 (en) * 1995-04-29 1995-06-21 Zeneca Ltd Substituted heterocycles
US5719156A (en) * 1995-05-02 1998-02-17 Schering Corporation Piperazino derivatives as neurokinin antagonists
GB9521781D0 (en) * 1995-10-24 1996-01-03 Merck Sharp & Dohme Therapeutic agents
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
WO1998031364A1 (en) * 1997-01-21 1998-07-23 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
US6124319A (en) * 1997-01-21 2000-09-26 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US7671200B2 (en) 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
US6281248B1 (en) 2000-02-16 2001-08-28 Magda Abdel Fattah Ahmed Composition for treating asthma
US6846814B2 (en) 2000-04-06 2005-01-25 Astra Zeneca Ab Neurokinin antagonists for use as medicaments
US7121402B2 (en) * 2003-04-09 2006-10-17 Reactive Nano Technologies, Inc Container hermetically sealed with crushable material and reactive multilayer material
US20050142495A1 (en) * 2003-10-09 2005-06-30 David Peter Van Heerden Methods of controlling multilayer foil ignition
US7441688B2 (en) * 2003-11-04 2008-10-28 Reactive Nanotechnologies Methods and device for controlling pressure in reactive multilayer joining and resulting product
DK1362844T3 (da) 2001-01-26 2008-04-14 Btg Int Ltd Benzylaminanalog
EP1626836A2 (en) * 2003-05-13 2006-02-22 Reactive Nanotechnologies Inc. Method of controlling thermal waves in reactive multilayer joining and resulting product
JP2008503482A (ja) 2004-06-18 2008-02-07 ワイス ６−アルキル−５−アリールスルホニル−ジヒドロフェナントリジンの製造方法
EP2870140B8 (en) 2012-07-09 2016-09-28 Lupin Limited Tetrahydroquinazolinone derivatives as parp inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI97540C (fi) * 1989-11-06 1997-01-10 Sanofi Sa Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676053B1 (fr) * 1991-05-03 1993-08-27 Sanofi Elf Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676054B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2688219B1 (fr) * 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
GB9321557D0 (en) * 1992-11-03 1993-12-08 Zeneca Ltd Carboxamide derivatives
GB9310066D0 (en) * 1993-05-17 1993-06-30 Zeneca Ltd Alkyl substituted heterocycles
GB9310713D0 (en) * 1993-05-24 1993-07-07 Zeneca Ltd Aryl substituted heterocycles
CA2163995A1 (en) * 1993-06-07 1994-12-22 Malcolm Maccoss Spiro-substituted azacycles as neurokinin antagonists
GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives

Also Published As

Publication number Publication date
AU690951B2 (en) 1998-05-07
PL315035A1 (en) 1996-09-30
ES2179094T3 (es) 2003-01-16
US5705505A (en) 1998-01-06
IL111970A0 (en) 1995-03-15
JP3819934B2 (ja) 2006-09-13
NO962543L (no) 1996-08-14
FI962418A0 (fi) 1996-06-11
WO1995016682A1 (en) 1995-06-22
HUT76275A (en) 1997-07-28
NO962543D0 (no) 1996-06-14
PT734383E (pt) 2002-12-31
EP0734383A1 (en) 1996-10-02
DE69431069T2 (de) 2003-05-08
DK0734383T3 (da) 2002-10-14
HU9601568D0 (en) 1996-08-28
FI962418A (fi) 1996-06-11
SG52667A1 (en) 1998-09-28
AU1247195A (en) 1995-07-03
BR9408325A (pt) 1997-08-19
CN1142822A (zh) 1997-02-12
DE69431069D1 (de) 2002-08-29
IL111970A (en) 1999-03-12
US5965576A (en) 1999-10-12
CA2176036A1 (en) 1995-06-22
JPH09506608A (ja) 1997-06-30
NZ277291A (en) 1997-12-19
US5589489A (en) 1996-12-31
CZ171796A3 (en) 1996-09-11
ATE221064T1 (de) 2002-08-15
EP0734383B1 (en) 2002-07-24

Similar Documents

Publication Publication Date Title
SK76396A3 (en) Cyclic amide derivatives, preparation method thereof and pharmaceutical compositions containing them
EP1554243B1 (en) Bicyclic benzamide compounds as histamine h3 receptor ligand useful in the treatment of neurological diseases
US6248747B1 (en) 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines
JP3534765B2 (ja) 喘息治療用のニューロキニン２受容体拮抗薬としての新規な４−ピペリジニル置換ラクタム
SK281941B6 (sk) Deriváty kyseliny indol-2-karboxylovej, ich použitie, spôsob ich prípravy a farmaceutický prípravok s ich obsahom
JPH08208605A (ja) 治療用複素環式化合物
JPH05140149A (ja) 縮合複素環誘導体
IL179437A (en) Benzimidazol-2-ylidene propane-1,3-dione derivatives and pharmaceutical compositions thereof
US5602138A (en) NKA affecting piperidyl heterobicyclic compounds
JP2014001227A (ja) キノロン化合物及び医薬組成物
US5635509A (en) Piperidine derivatives useful as neurokinin antagonists
US20040053956A1 (en) Isoquinoline derivatives useful in the treatment of cns disorders
EP0739891B1 (en) Substituted heterocycles
KR0179985B1 (ko) 류코트리엔 길항제로서 유용한 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물
JP5769504B2 (ja) 医薬
FI94863B (fi) Menetelmä terapeuttisesti käyttökelpoisten halogeeni-3,4-dihydro-bentsotiopyranyyliamiinien valmistamiseksi
CZ20002757A3 (cs) 2.3.4.5-tetrahydro-lH/l,4/-benzodiazepin-3- hydroxamové kyseliny