SK4562000A3 - 3'-N-MODIFIED 6-O-SUBSTITUTED ERYTHROMYCIN KETOLIDE DERIVATIVESì (54) HAVING ANTIBACTERIAL ACTIVITY - Google Patents

3'-N-MODIFIED 6-O-SUBSTITUTED ERYTHROMYCIN KETOLIDE DERIVATIVESì (54) HAVING ANTIBACTERIAL ACTIVITY Download PDF

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Publication number
SK4562000A3
SK4562000A3 SK456-2000A SK4562000A SK4562000A3 SK 4562000 A3 SK4562000 A3 SK 4562000A3 SK 4562000 A SK4562000 A SK 4562000A SK 4562000 A3 SK4562000 A3 SK 4562000A3
Authority
SK
Slovakia
Prior art keywords
substituted
alkyl
defined above
heteroaryl
formula
Prior art date
Application number
SK456-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Yat Sun Or
Zhenkun Ma
Daniel T Chu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of SK4562000A3 publication Critical patent/SK4562000A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
SK456-2000A 1997-09-30 1998-09-16 3'-N-MODIFIED 6-O-SUBSTITUTED ERYTHROMYCIN KETOLIDE DERIVATIVESì (54) HAVING ANTIBACTERIAL ACTIVITY SK4562000A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94087197A 1997-09-30 1997-09-30
US13312198A 1998-08-12 1998-08-12
PCT/US1998/019311 WO1999016779A1 (en) 1997-09-30 1998-09-16 3'-n-modified 6-o-substituted erythromycin ketolide derivatives having antibacterial activity

Publications (1)

Publication Number Publication Date
SK4562000A3 true SK4562000A3 (en) 2000-09-12

Family

ID=26831064

Family Applications (1)

Application Number Title Priority Date Filing Date
SK456-2000A SK4562000A3 (en) 1997-09-30 1998-09-16 3'-N-MODIFIED 6-O-SUBSTITUTED ERYTHROMYCIN KETOLIDE DERIVATIVESì (54) HAVING ANTIBACTERIAL ACTIVITY

Country Status (22)

Country Link
EP (1) EP1025114B1 (da)
JP (1) JP2001518476A (da)
KR (1) KR20010030807A (da)
CN (1) CN1271363A (da)
AR (1) AR015727A1 (da)
AT (1) ATE260293T1 (da)
AU (1) AU737310B2 (da)
BG (1) BG104340A (da)
BR (1) BR9812577A (da)
CA (1) CA2303930A1 (da)
CO (1) CO4990958A1 (da)
DE (1) DE69821964T2 (da)
DK (1) DK1025114T3 (da)
ES (1) ES2217579T3 (da)
HU (1) HUP0004579A3 (da)
IL (1) IL134608A0 (da)
NO (1) NO20001439L (da)
PL (1) PL339575A1 (da)
PT (1) PT1025114E (da)
SK (1) SK4562000A3 (da)
TR (1) TR200000805T2 (da)
WO (1) WO1999016779A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
KR100710605B1 (ko) * 1999-04-16 2007-04-24 코산 바이오사이언시즈, 인코포레이티드 매크롤라이드 항감염제
US6355620B1 (en) * 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
CA2417319A1 (en) * 2000-08-14 2003-01-27 Taisho Pharmaceutical Co., Ltd. Process for producing erythromycin derivative
US20020111317A1 (en) * 2000-09-25 2002-08-15 Leonard Katz Sixteen-membered macrolide compounds
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
US8202843B2 (en) * 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
CN108101948A (zh) * 2004-02-27 2018-06-01 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
BRPI0513903A (pt) * 2004-07-28 2008-05-20 Ranbaxy Lab Ltd derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos
WO2006046112A2 (en) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
WO2006129257A2 (en) * 2005-05-30 2006-12-07 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
WO2007025284A1 (en) * 2005-08-24 2007-03-01 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
WO2007025089A2 (en) 2005-08-24 2007-03-01 Rib-X Pharmaceutical, Inc. Triazole compounds and methods of making and using the same
WO2007060518A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
JP5126685B2 (ja) * 2006-05-01 2013-01-23 大正製薬株式会社 マクロライド誘導体
WO2008099368A1 (en) * 2007-02-15 2008-08-21 Ranbaxy Laboratories Limited Macrolide derivatives as antibacterial agents
WO2008111020A2 (en) * 2007-03-14 2008-09-18 Ranbaxy Laboratories Limited Macrolide derivatives as antibacterial agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
DE69631609T2 (de) * 1995-11-08 2005-01-05 Abbott Laboratories, Abbott Park Tricyclische erythromycinderivate

Also Published As

Publication number Publication date
AR015727A1 (es) 2001-05-16
WO1999016779A1 (en) 1999-04-08
JP2001518476A (ja) 2001-10-16
TR200000805T2 (tr) 2000-10-23
CO4990958A1 (es) 2000-12-26
EP1025114B1 (en) 2004-02-25
DK1025114T3 (da) 2004-07-05
PL339575A1 (en) 2000-12-18
PT1025114E (pt) 2004-07-30
NO20001439L (no) 2000-05-29
CN1271363A (zh) 2000-10-25
IL134608A0 (en) 2001-04-30
ES2217579T3 (es) 2004-11-01
ATE260293T1 (de) 2004-03-15
DE69821964D1 (de) 2004-04-01
BR9812577A (pt) 2000-10-17
EP1025114A1 (en) 2000-08-09
AU9317698A (en) 1999-04-23
BG104340A (en) 2001-01-31
HUP0004579A3 (en) 2001-11-28
NO20001439D0 (no) 2000-03-20
DE69821964T2 (de) 2004-12-30
KR20010030807A (ko) 2001-04-16
CA2303930A1 (en) 1999-04-08
HUP0004579A2 (hu) 2001-05-28
AU737310B2 (en) 2001-08-16

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