SK431290A3 - Process for the preparation of stable concentrate of factor viii - von willebrand factor complex having high specific activity - Google Patents

Process for the preparation of stable concentrate of factor viii - von willebrand factor complex having high specific activity Download PDF

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Publication number
SK431290A3
SK431290A3 SK4312-90A SK431290A SK431290A3 SK 431290 A3 SK431290 A3 SK 431290A3 SK 431290 A SK431290 A SK 431290A SK 431290 A3 SK431290 A3 SK 431290A3
Authority
SK
Slovakia
Prior art keywords
buffer
carried out
plasma
factor viii
sodium chloride
Prior art date
Application number
SK4312-90A
Other languages
English (en)
Slovak (sk)
Other versions
SK279367B6 (sk
Inventor
Miryana Burnouf-Radosevich
Thierry Burnouf
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of SK279367B6 publication Critical patent/SK279367B6/sk
Publication of SK431290A3 publication Critical patent/SK431290A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
SK4312-90A 1989-09-05 1990-09-05 Process for the preparation of stable concentrate of factor viii - von willebrand factor complex having high specific activity SK431290A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8911567A FR2651437A1 (fr) 1989-09-05 1989-09-05 Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.

Publications (2)

Publication Number Publication Date
SK279367B6 SK279367B6 (sk) 1998-10-07
SK431290A3 true SK431290A3 (en) 1998-10-07

Family

ID=9385124

Family Applications (1)

Application Number Title Priority Date Filing Date
SK4312-90A SK431290A3 (en) 1989-09-05 1990-09-05 Process for the preparation of stable concentrate of factor viii - von willebrand factor complex having high specific activity

Country Status (24)

Country Link
US (1) US5679776A (lt)
EP (1) EP0416983B1 (lt)
AT (1) ATE91896T1 (lt)
AU (1) AU627618B2 (lt)
BR (1) BR9004626A (lt)
CA (1) CA2024667C (lt)
CZ (1) CZ277939B6 (lt)
DD (1) DD298110A5 (lt)
DE (1) DE69002427T2 (lt)
DK (1) DK0416983T3 (lt)
ES (1) ES2057475T3 (lt)
FI (1) FI95654C (lt)
FR (1) FR2651437A1 (lt)
HR (1) HRP920768B1 (lt)
HU (1) HU206378B (lt)
LT (1) LT3418B (lt)
LV (1) LV10053B (lt)
NO (1) NO178716C (lt)
PL (1) PL164754B1 (lt)
RU (1) RU2025129C1 (lt)
SI (1) SI9012034B (lt)
SK (1) SK431290A3 (lt)
UA (1) UA26847C2 (lt)
YU (1) YU48356B (lt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3904354A1 (de) * 1989-02-14 1990-08-16 Behringwerke Ag Pasteurisiertes, gereinigtes von willebrand-faktor-konzentrat und verfahren zu seiner herstellung
DK0399321T3 (da) * 1989-05-24 1993-08-09 Miles Inc Gelfiltrering af varmebehandlet faktor VIII
AT403991B (de) * 1990-04-04 1998-07-27 Atomic Austria Gmbh Alpinschi
AT403992B (de) * 1991-02-22 1998-07-27 Head Sport Ag Ski
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie
IT1256622B (it) * 1992-12-04 1995-12-12 Sclavo Spa Processo per l'estrazione del complesso fattore viii-fattore von willebrand (fviii:c-fvw) da plasma umano totale.
DE4430205A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung
DE4435485C1 (de) * 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
AT403765B (de) 1996-04-12 1998-05-25 Immuno Ag Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
CN1284881A (zh) * 1997-11-05 2001-02-21 吉富制药株式会社 肝素辅助因子ⅱ制剂及其制备方法
EP0937735B1 (en) * 1998-02-11 2003-02-26 ZLB Bioplasma AG A method for the removal of causative agent(s) of transmissible spongiform encephalopathies from protein solutions
DE60035260T2 (de) 1999-02-22 2007-10-18 The University Of Connecticut, Farmington Neue albuminfreie faktor viii formulierungen
DE19937218A1 (de) * 1999-08-06 2001-02-08 Aventis Behring Gmbh Verfahren zur Reindarstellung der den Blutgerinnungsfaktor VII aktivierenden Protease, ihres Proenzyms oder eines Gemisches beider Proteine mittels Affinitätschromatographie
ES2229931B1 (es) * 2003-10-03 2006-01-16 Grifols, S.A. Composicion liquida bilogicamente estable de fviii, de fvw o del complejo fviii/fvw humanos.
FR2874216B1 (fr) 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
WO2013083858A1 (en) 2012-04-24 2013-06-13 Novo Nordisk A/S Compounds suitable for treatment of haemophilia
ES2693380T3 (es) * 2013-11-08 2018-12-11 Csl Limited Nuevo método para concentrar el factor de von Willebrand o complejos de este
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
CN104231073B (zh) * 2014-09-25 2017-01-25 广东双林生物制药有限公司 一种人凝血因子viii的制备方法
CN105315365A (zh) * 2015-11-17 2016-02-10 上海洲跃生物科技有限公司 一种人抗凝血酶iii的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803115A (en) * 1972-05-17 1974-04-09 Baxter Laboratories Inc Stabilization of ahf using heparin
ES471858A1 (es) * 1977-07-25 1979-02-01 Monsanto Co Un metodo para separar el factor especifico de coagulacion de la sangre de una mezcla con otras proteinas de la sangre en un medio fluido
US4386068A (en) * 1980-02-26 1983-05-31 Cutter Laboratories, Inc. Antihemophilic factor concentrate and method for preparation
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
US4435318A (en) * 1981-05-22 1984-03-06 Ionics, Incorporated Electrodialysis preparation of purified AHF concentrate
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
US4952675A (en) * 1985-02-01 1990-08-28 New York University Method for purifying antihemophilic factor
FR2632309B1 (fr) 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus

Also Published As

Publication number Publication date
YU48356B (sh) 1998-07-10
CA2024667C (en) 2001-07-31
DE69002427T2 (de) 1993-12-23
CZ277939B6 (en) 1993-06-16
RU2025129C1 (ru) 1994-12-30
HRP920768B1 (en) 1998-12-31
DD298110A5 (de) 1992-02-06
ATE91896T1 (de) 1993-08-15
HRP920768A2 (en) 1995-02-28
FI904381A0 (fi) 1990-09-05
BR9004626A (pt) 1992-03-24
AU627618B2 (en) 1992-08-27
SK279367B6 (sk) 1998-10-07
HU206378B (en) 1992-10-28
FI95654B (fi) 1995-11-30
LTIP263A (en) 1994-10-25
CA2024667A1 (en) 1991-03-06
AU6221890A (en) 1992-03-12
NO178716C (no) 1996-05-22
NO903865L (no) 1991-03-06
EP0416983A1 (fr) 1991-03-13
LV10053B (en) 1995-02-20
CZ431290A3 (en) 1993-01-13
FI95654C (fi) 1996-03-11
US5679776A (en) 1997-10-21
PL286746A1 (en) 1991-05-06
HUT56858A (en) 1991-10-28
NO178716B (no) 1996-02-12
FR2651437A1 (fr) 1991-03-08
ES2057475T3 (es) 1994-10-16
EP0416983B1 (fr) 1993-07-28
HU905797D0 (en) 1991-03-28
NO903865D0 (no) 1990-09-05
PL164754B1 (pl) 1994-10-31
FR2651437B1 (lt) 1994-08-19
UA26847C2 (uk) 1999-12-29
LV10053A (lv) 1994-05-10
LT3418B (en) 1995-09-25
DE69002427D1 (de) 1993-09-02
SI9012034B (sl) 1999-12-31
SI9012034A (en) 1997-10-31
DK0416983T3 (da) 1993-10-04
YU203490A (sh) 1993-05-28

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20090905