SK399A3 - Benzo[g]quinoline derivatives, process for their preparation, pharmaceutical composition containing same and their use - Google Patents

Benzo[g]quinoline derivatives, process for their preparation, pharmaceutical composition containing same and their use Download PDF

Info

Publication number
SK399A3
SK399A3 SK3-99A SK399A SK399A3 SK 399 A3 SK399 A3 SK 399A3 SK 399 A SK399 A SK 399A SK 399 A3 SK399 A3 SK 399A3
Authority
SK
Slovakia
Prior art keywords
free base
compound
formula
methyl
acid salt
Prior art date
Application number
SK3-99A
Other languages
English (en)
Slovak (sk)
Inventor
Peter Gull
Rudolf Markstein
Max P Seiler
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9614282.3A external-priority patent/GB9614282D0/en
Priority claimed from GBGB9626093.0A external-priority patent/GB9626093D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK399A3 publication Critical patent/SK399A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK3-99A 1996-07-08 1997-07-07 Benzo[g]quinoline derivatives, process for their preparation, pharmaceutical composition containing same and their use SK399A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9614282.3A GB9614282D0 (en) 1996-07-08 1996-07-08 Organic compounds
GBGB9626093.0A GB9626093D0 (en) 1996-12-16 1996-12-16 Organic compounds
PCT/EP1997/003582 WO1998001444A1 (en) 1996-07-08 1997-07-07 BENZO[g]QUINOLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
SK399A3 true SK399A3 (en) 1999-06-11

Family

ID=26309658

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3-99A SK399A3 (en) 1996-07-08 1997-07-07 Benzo[g]quinoline derivatives, process for their preparation, pharmaceutical composition containing same and their use

Country Status (28)

Country Link
US (1) US6057334A (xx)
EP (1) EP0912553B1 (xx)
JP (1) JP4216337B2 (xx)
KR (1) KR100491478B1 (xx)
CN (1) CN1125065C (xx)
AR (1) AR007814A1 (xx)
AT (1) ATE211470T1 (xx)
AU (1) AU719119B2 (xx)
BR (1) BR9710218A (xx)
CA (1) CA2257646C (xx)
CO (1) CO4870760A1 (xx)
CY (1) CY2322B1 (xx)
CZ (1) CZ2799A3 (xx)
DE (1) DE69709869T2 (xx)
DK (1) DK0912553T3 (xx)
ES (1) ES2170402T3 (xx)
HK (1) HK1020569A1 (xx)
ID (1) ID18896A (xx)
IL (1) IL127376A (xx)
NO (1) NO319401B1 (xx)
NZ (1) NZ333311A (xx)
PE (1) PE87998A1 (xx)
PL (1) PL330723A1 (xx)
PT (1) PT912553E (xx)
SK (1) SK399A3 (xx)
TR (1) TR199900016T2 (xx)
TW (1) TW378209B (xx)
WO (1) WO1998001444A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA
EG24415A (en) 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
SI1757601T1 (sl) * 2002-03-07 2009-12-31 Novartis Ag Kinolinski derivati in njihova uporaba pri glavkomu in miopiji
US20070093507A1 (en) * 2003-09-05 2007-04-26 Lambrou George N Compositions comprising benzo (g) quinoline derivatives and prostaglandin derivatives
CN105434439B (zh) * 2015-11-11 2018-07-24 温州医科大学 一种多巴胺d2受体的部分激动剂在制备抑制近视药物上的应用及其使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19575006I2 (de) * 1981-10-16 2003-01-09 Novartis Ag 1, 2, 3, 4a, 5, 10, 10a-Octahydrobenzo(g)chinolin-Derivate mit pharmazeutischer Wirkung
AU3879789A (en) * 1988-07-22 1990-02-19 Sandoz Ag Use of benzo(g)quinolines in treatment of nicotine addiction
GB8829330D0 (en) * 1988-12-16 1989-02-01 Sandoz Ltd Improvements in or relating to organic compounds
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
FR2729145A1 (fr) * 1995-01-06 1996-07-12 Smithkline Beecham Lab Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques

Also Published As

Publication number Publication date
AU3542297A (en) 1998-02-02
AR007814A1 (es) 1999-11-24
US6057334A (en) 2000-05-02
PL330723A1 (en) 1999-05-24
IL127376A0 (en) 1999-10-28
AU719119B2 (en) 2000-05-04
CA2257646A1 (en) 1998-01-15
BR9710218A (pt) 1999-08-10
DE69709869T2 (de) 2002-08-14
CZ2799A3 (cs) 1999-03-17
PE87998A1 (es) 1998-12-30
WO1998001444A1 (en) 1998-01-15
CN1225093A (zh) 1999-08-04
JP4216337B2 (ja) 2009-01-28
DE69709869D1 (de) 2002-02-28
ID18896A (id) 1998-05-20
IL127376A (en) 2003-12-10
ATE211470T1 (de) 2002-01-15
EP0912553B1 (en) 2002-01-02
CN1125065C (zh) 2003-10-22
KR20000023572A (ko) 2000-04-25
NO990035D0 (no) 1999-01-05
CY2322B1 (en) 2003-11-14
JP2000514075A (ja) 2000-10-24
NZ333311A (en) 2000-06-23
HK1020569A1 (en) 2000-05-12
CO4870760A1 (es) 1999-12-27
NO319401B1 (no) 2005-08-08
EP0912553A1 (en) 1999-05-06
PT912553E (pt) 2002-06-28
DK0912553T3 (da) 2002-04-22
TR199900016T2 (xx) 1999-04-21
TW378209B (en) 2000-01-01
KR100491478B1 (ko) 2005-05-27
ES2170402T3 (es) 2002-08-01
CA2257646C (en) 2006-05-09
NO990035L (no) 1999-01-05

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