DE69709869D1 - BENZO[g]CHINOLIN DERIVATE - Google Patents

BENZO[g]CHINOLIN DERIVATE

Info

Publication number
DE69709869D1
DE69709869D1 DE69709869T DE69709869T DE69709869D1 DE 69709869 D1 DE69709869 D1 DE 69709869D1 DE 69709869 T DE69709869 T DE 69709869T DE 69709869 T DE69709869 T DE 69709869T DE 69709869 D1 DE69709869 D1 DE 69709869D1
Authority
DE
Germany
Prior art keywords
benzo
chinoline derivatives
chinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69709869T
Other languages
English (en)
Other versions
DE69709869T2 (de
Inventor
Peter Gull
Rudolf Markstein
Peter Seiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH
Novartis AG
Original Assignee
Novartis Erfindungen Verwaltungs GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9614282.3A external-priority patent/GB9614282D0/en
Priority claimed from GBGB9626093.0A external-priority patent/GB9626093D0/en
Application filed by Novartis Erfindungen Verwaltungs GmbH, Novartis AG filed Critical Novartis Erfindungen Verwaltungs GmbH
Application granted granted Critical
Publication of DE69709869D1 publication Critical patent/DE69709869D1/de
Publication of DE69709869T2 publication Critical patent/DE69709869T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69709869T 1996-07-08 1997-07-07 BENZO[g]CHINOLIN DERIVATE Expired - Lifetime DE69709869T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9614282.3A GB9614282D0 (en) 1996-07-08 1996-07-08 Organic compounds
GBGB9626093.0A GB9626093D0 (en) 1996-12-16 1996-12-16 Organic compounds
PCT/EP1997/003582 WO1998001444A1 (en) 1996-07-08 1997-07-07 BENZO[g]QUINOLINE DERIVATIVES

Publications (2)

Publication Number Publication Date
DE69709869D1 true DE69709869D1 (de) 2002-02-28
DE69709869T2 DE69709869T2 (de) 2002-08-14

Family

ID=26309658

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69709869T Expired - Lifetime DE69709869T2 (de) 1996-07-08 1997-07-07 BENZO[g]CHINOLIN DERIVATE

Country Status (28)

Country Link
US (1) US6057334A (de)
EP (1) EP0912553B1 (de)
JP (1) JP4216337B2 (de)
KR (1) KR100491478B1 (de)
CN (1) CN1125065C (de)
AR (1) AR007814A1 (de)
AT (1) ATE211470T1 (de)
AU (1) AU719119B2 (de)
BR (1) BR9710218A (de)
CA (1) CA2257646C (de)
CO (1) CO4870760A1 (de)
CY (1) CY2322B1 (de)
CZ (1) CZ2799A3 (de)
DE (1) DE69709869T2 (de)
DK (1) DK0912553T3 (de)
ES (1) ES2170402T3 (de)
HK (1) HK1020569A1 (de)
ID (1) ID18896A (de)
IL (1) IL127376A (de)
NO (1) NO319401B1 (de)
NZ (1) NZ333311A (de)
PE (1) PE87998A1 (de)
PL (1) PL330723A1 (de)
PT (1) PT912553E (de)
SK (1) SK399A3 (de)
TR (1) TR199900016T2 (de)
TW (1) TW378209B (de)
WO (1) WO1998001444A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA
EG24415A (en) * 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
ES2328618T3 (es) * 2002-03-07 2009-11-16 Novartis Ag Derivados de la quinolina y su utilizacion en el glaucoma y la miopia.
JP2007504198A (ja) * 2003-09-05 2007-03-01 ノバルティス アクチエンゲゼルシャフト ベンゾ[g]キノリン誘導体とプロスタグランジン誘導体を含む、組成物
CN105434439B (zh) * 2015-11-11 2018-07-24 温州医科大学 一种多巴胺d2受体的部分激动剂在制备抑制近视药物上的应用及其使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3280252D1 (de) * 1981-10-16 1990-10-31 Sandoz Ag 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolin-derivate mit pharmazeutischer wirkung.
WO1990000896A1 (en) * 1988-07-22 1990-02-08 Sandoz Ag USE OF BENZO(g)QUINOLINES IN TREATMENT OF NICOTINE ADDICTION
GB8829330D0 (en) * 1988-12-16 1989-02-01 Sandoz Ltd Improvements in or relating to organic compounds
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
FR2729145A1 (fr) * 1995-01-06 1996-07-12 Smithkline Beecham Lab Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques

Also Published As

Publication number Publication date
TW378209B (en) 2000-01-01
CN1125065C (zh) 2003-10-22
NO990035L (no) 1999-01-05
CZ2799A3 (cs) 1999-03-17
CO4870760A1 (es) 1999-12-27
CY2322B1 (en) 2003-11-14
SK399A3 (en) 1999-06-11
AU3542297A (en) 1998-02-02
NO319401B1 (no) 2005-08-08
ATE211470T1 (de) 2002-01-15
CA2257646A1 (en) 1998-01-15
DE69709869T2 (de) 2002-08-14
DK0912553T3 (da) 2002-04-22
PL330723A1 (en) 1999-05-24
ES2170402T3 (es) 2002-08-01
HK1020569A1 (en) 2000-05-12
WO1998001444A1 (en) 1998-01-15
KR100491478B1 (ko) 2005-05-27
JP2000514075A (ja) 2000-10-24
IL127376A0 (en) 1999-10-28
PE87998A1 (es) 1998-12-30
ID18896A (id) 1998-05-20
AU719119B2 (en) 2000-05-04
KR20000023572A (ko) 2000-04-25
CA2257646C (en) 2006-05-09
AR007814A1 (es) 1999-11-24
BR9710218A (pt) 1999-08-10
NO990035D0 (no) 1999-01-05
JP4216337B2 (ja) 2009-01-28
EP0912553A1 (de) 1999-05-06
US6057334A (en) 2000-05-02
EP0912553B1 (de) 2002-01-02
CN1225093A (zh) 1999-08-04
PT912553E (pt) 2002-06-28
TR199900016T2 (xx) 1999-04-21
NZ333311A (en) 2000-06-23
IL127376A (en) 2003-12-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN