IL127376A - BENZO[g] QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM - Google Patents

BENZO[g] QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Info

Publication number
IL127376A
IL127376A IL12737697A IL12737697A IL127376A IL 127376 A IL127376 A IL 127376A IL 12737697 A IL12737697 A IL 12737697A IL 12737697 A IL12737697 A IL 12737697A IL 127376 A IL127376 A IL 127376A
Authority
IL
Israel
Prior art keywords
benzo
preparation
pharmaceutical compositions
quinoline derivatives
quinoline
Prior art date
Application number
IL12737697A
Other languages
English (en)
Other versions
IL127376A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9614282.3A external-priority patent/GB9614282D0/en
Priority claimed from GBGB9626093.0A external-priority patent/GB9626093D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL127376A0 publication Critical patent/IL127376A0/xx
Publication of IL127376A publication Critical patent/IL127376A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12737697A 1996-07-08 1997-07-07 BENZO[g] QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM IL127376A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9614282.3A GB9614282D0 (en) 1996-07-08 1996-07-08 Organic compounds
GBGB9626093.0A GB9626093D0 (en) 1996-12-16 1996-12-16 Organic compounds
PCT/EP1997/003582 WO1998001444A1 (en) 1996-07-08 1997-07-07 BENZO[g]QUINOLINE DERIVATIVES

Publications (2)

Publication Number Publication Date
IL127376A0 IL127376A0 (en) 1999-10-28
IL127376A true IL127376A (en) 2003-12-10

Family

ID=26309658

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12737697A IL127376A (en) 1996-07-08 1997-07-07 BENZO[g] QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Country Status (28)

Country Link
US (1) US6057334A (de)
EP (1) EP0912553B1 (de)
JP (1) JP4216337B2 (de)
KR (1) KR100491478B1 (de)
CN (1) CN1125065C (de)
AR (1) AR007814A1 (de)
AT (1) ATE211470T1 (de)
AU (1) AU719119B2 (de)
BR (1) BR9710218A (de)
CA (1) CA2257646C (de)
CO (1) CO4870760A1 (de)
CY (1) CY2322B1 (de)
CZ (1) CZ2799A3 (de)
DE (1) DE69709869T2 (de)
DK (1) DK0912553T3 (de)
ES (1) ES2170402T3 (de)
HK (1) HK1020569A1 (de)
ID (1) ID18896A (de)
IL (1) IL127376A (de)
NO (1) NO319401B1 (de)
NZ (1) NZ333311A (de)
PE (1) PE87998A1 (de)
PL (1) PL330723A1 (de)
PT (1) PT912553E (de)
SK (1) SK399A3 (de)
TR (1) TR199900016T2 (de)
TW (1) TW378209B (de)
WO (1) WO1998001444A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA
ES2328618T3 (es) * 2002-03-07 2009-11-16 Novartis Ag Derivados de la quinolina y su utilizacion en el glaucoma y la miopia.
EG24415A (en) * 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
EP1663230A1 (de) * 2003-09-05 2006-06-07 Novartis AG Zusammensetzungen mit benzo(g)chinolin-derivaten und prostaglandin-derivaten
CN105434439B (zh) * 2015-11-11 2018-07-24 温州医科大学 一种多巴胺d2受体的部分激动剂在制备抑制近视药物上的应用及其使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077754B1 (de) * 1981-10-16 1990-09-26 Sandoz Ag 1,2,3,4,4a,5,10,10a-Octahydrobenzo(g)chinolin-Derivate mit pharmazeutischer Wirkung
WO1990000896A1 (en) * 1988-07-22 1990-02-08 Sandoz Ag USE OF BENZO(g)QUINOLINES IN TREATMENT OF NICOTINE ADDICTION
GB8829330D0 (en) * 1988-12-16 1989-02-01 Sandoz Ltd Improvements in or relating to organic compounds
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
FR2729145A1 (fr) * 1995-01-06 1996-07-12 Smithkline Beecham Lab Nouveaux derives d'amine, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques

Also Published As

Publication number Publication date
SK399A3 (en) 1999-06-11
KR100491478B1 (ko) 2005-05-27
NZ333311A (en) 2000-06-23
NO319401B1 (no) 2005-08-08
ID18896A (id) 1998-05-20
PL330723A1 (en) 1999-05-24
AR007814A1 (es) 1999-11-24
TW378209B (en) 2000-01-01
NO990035L (no) 1999-01-05
CN1125065C (zh) 2003-10-22
BR9710218A (pt) 1999-08-10
EP0912553B1 (de) 2002-01-02
DE69709869T2 (de) 2002-08-14
WO1998001444A1 (en) 1998-01-15
KR20000023572A (ko) 2000-04-25
TR199900016T2 (xx) 1999-04-21
EP0912553A1 (de) 1999-05-06
ES2170402T3 (es) 2002-08-01
CO4870760A1 (es) 1999-12-27
CN1225093A (zh) 1999-08-04
AU3542297A (en) 1998-02-02
CZ2799A3 (cs) 1999-03-17
DK0912553T3 (da) 2002-04-22
HK1020569A1 (en) 2000-05-12
NO990035D0 (no) 1999-01-05
CY2322B1 (en) 2003-11-14
US6057334A (en) 2000-05-02
ATE211470T1 (de) 2002-01-15
CA2257646A1 (en) 1998-01-15
PT912553E (pt) 2002-06-28
JP4216337B2 (ja) 2009-01-28
AU719119B2 (en) 2000-05-04
PE87998A1 (es) 1998-12-30
IL127376A0 (en) 1999-10-28
CA2257646C (en) 2006-05-09
DE69709869D1 (de) 2002-02-28
JP2000514075A (ja) 2000-10-24

Similar Documents

Publication Publication Date Title
HUP9700358A3 (en) New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0100397A3 (en) Tetrahydro- or octahydrobenzonaphtyridin and quinolin derivatives, pharmaceutical compositions thereof and process for their preparation
HUP0104582A3 (en) 1,2-annelated quinoline derivatives, pharmaceutical compositions thereof, intermediates and process for their preparation
HUP9904680A3 (en) Thienopyrimidine derivatives, pharmaceutical compositions containing them and process for their preparation
HUP0100431A3 (en) Adamantana derivatives, pharmaceutical compositions comprising them and process for preparing them
HUP0102084A3 (en) Quinoline derivatives, process for producing them and pharmaceutical compositions containing them
HUP0103224A3 (en) Quinoline derivatives, process for producing them and pharmaceutical compositions containing them
HUP0001555A3 (en) Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
IL127798A (en) N-substituted indol-3-glyoxylamides, process for their preparation and pharmaceutical compositions comprising them
IL120141A (en) Substituted quinazoline derivatives process for their preparation and pharmaceutical compositions containing them
HUP9602122A2 (en) Camptothecin derivatives, process for the preparation thereof and pharmaceutical compositions containing them
HUT76286A (en) Quinoline derivatives, pharmaceutical compositions containing them, process for producing them and their use
HUP0102307A3 (en) Bispidine derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
HUP0104762A3 (en) Pharmaceutical moxifloxacin compositions and process for their preparation
HUP0004747A3 (en) 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinoline derivatives and process for their preparation
IL125622A (en) Erythromycin derivatives, method for preparing same and pharmaceutical compositions comprising them
IL122854A0 (en) Benzo [g] quinoline derivatives their preparation and pharmaceutical preparation containing them
HUP0201516A2 (en) 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
HUP9702400A3 (en) Substituted camptothecin derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0002300A3 (en) Quinoline-4-carboxamide derivatives, process for producing them, pharmaceutical compositions containing them and their use
HUP0001385A3 (en) Pro-drugs and derivatives of camptothecin, process for their preparation, use thereof and pharmaceutical compositions containing them
HUP0104520A3 (en) Substituted benzo[de]isoquinoline-1,3-diones process for their preparation and pharmaceutical compositions containing them
HUP0003624A3 (en) 1,2,3,4-tetrahydro-benzofuro[3,2-c]pyridine derivatives, pharmaceutical compositions containing them and process for their preparation
HUP9900987A3 (en) Camptothecin derivatives process for their preparation, use thereof as antitumor agents and pharmaceutical compositions containing them
HUP9904514A3 (en) 5h-pyrrolo[2,1-c][1,4]-benzodiazepin 3-carboxamide derivatives, process for their preparation, their use and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees