SK379692A3 - Stable salts of (+)-(1s,2r)-2-//n-(2-hydroxylamino-2- -oxoethyl)-n-methyl-amino/carbonyl/cyclohexan-1-carboxylic acid, method of their preparation and pharmaceutical agents containing these salts - Google Patents

Stable salts of (+)-(1s,2r)-2-//n-(2-hydroxylamino-2- -oxoethyl)-n-methyl-amino/carbonyl/cyclohexan-1-carboxylic acid, method of their preparation and pharmaceutical agents containing these salts Download PDF

Info

Publication number
SK379692A3
SK379692A3 SK3796-92A SK379692A SK379692A3 SK 379692 A3 SK379692 A3 SK 379692A3 SK 379692 A SK379692 A SK 379692A SK 379692 A3 SK379692 A3 SK 379692A3
Authority
SK
Slovakia
Prior art keywords
oxoethyl
carbonyl
salts
group
carboxylic acid
Prior art date
Application number
SK3796-92A
Other languages
English (en)
Slovak (sk)
Inventor
Raffaello Giorgi
Alessandro Subissi
Luigi Turbanti
Original Assignee
Guidotti & C Spa Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guidotti & C Spa Labor filed Critical Guidotti & C Spa Labor
Publication of SK379692A3 publication Critical patent/SK379692A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
SK3796-92A 1991-12-23 1992-12-21 Stable salts of (+)-(1s,2r)-2-//n-(2-hydroxylamino-2- -oxoethyl)-n-methyl-amino/carbonyl/cyclohexan-1-carboxylic acid, method of their preparation and pharmaceutical agents containing these salts SK379692A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI913448A IT1252708B (it) 1991-12-23 1991-12-23 Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.

Publications (1)

Publication Number Publication Date
SK379692A3 true SK379692A3 (en) 1995-04-12

Family

ID=11361409

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3796-92A SK379692A3 (en) 1991-12-23 1992-12-21 Stable salts of (+)-(1s,2r)-2-//n-(2-hydroxylamino-2- -oxoethyl)-n-methyl-amino/carbonyl/cyclohexan-1-carboxylic acid, method of their preparation and pharmaceutical agents containing these salts

Country Status (26)

Country Link
EP (1) EP0575572A1 (pt)
JP (1) JPH06506002A (pt)
CN (1) CN1079474A (pt)
AU (1) AU657591B2 (pt)
BG (1) BG98050A (pt)
BR (1) BR9205652A (pt)
CA (1) CA2104372A1 (pt)
CZ (1) CZ379692A3 (pt)
EE (1) EE9400006A (pt)
FI (1) FI933685A (pt)
HR (1) HRP921454A2 (pt)
HU (1) HUT69287A (pt)
IT (1) IT1252708B (pt)
LV (1) LV10426B (pt)
MA (1) MA22749A1 (pt)
MX (1) MX9207543A (pt)
NZ (1) NZ245547A (pt)
PL (1) PL169086B1 (pt)
PT (1) PT101156A (pt)
RU (1) RU2079489C1 (pt)
SI (1) SI9200409A (pt)
SK (1) SK379692A3 (pt)
TN (1) TNSN92117A1 (pt)
WO (1) WO1993013056A1 (pt)
YU (1) YU110892A (pt)
ZA (1) ZA9210004B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264860B1 (it) * 1993-06-21 1996-10-17 Guidotti & C Spa Labor Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici
US5639746A (en) * 1994-12-29 1997-06-17 The Procter & Gamble Company Hydroxamic acid-containing inhibitors of matrix metalloproteases
FR2817241B1 (fr) 2000-11-30 2003-03-07 Cebal Tube aluminium avec embout secable
JP2010504969A (ja) * 2006-09-28 2010-02-18 メルク エンド カムパニー インコーポレーテッド Sahaのアミン塩基塩及びその多形
WO2021221984A1 (en) * 2020-04-27 2021-11-04 Carter-Hoffmann, Llc Door movement system for cabinet

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224627B (it) * 1988-04-12 1990-10-04 Guidotti & C Spa Labor Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono.

Also Published As

Publication number Publication date
SI9200409A (en) 1993-09-30
CN1079474A (zh) 1993-12-15
YU110892A (sh) 1996-01-08
HRP921454A2 (en) 1995-02-28
ZA9210004B (en) 1993-12-13
WO1993013056A1 (en) 1993-07-08
MA22749A1 (fr) 1993-07-01
PL297118A1 (en) 1993-09-06
LV10426A (lv) 1995-02-20
ITMI913448A0 (it) 1991-12-23
PL169086B1 (pl) 1996-05-31
TNSN92117A1 (fr) 1993-06-08
JPH06506002A (ja) 1994-07-07
RU2079489C1 (ru) 1997-05-20
CA2104372A1 (en) 1993-06-24
FI933685A0 (fi) 1993-08-20
EE9400006A (et) 1995-12-15
LV10426B (en) 1995-08-20
BR9205652A (pt) 1994-05-03
AU657591B2 (en) 1995-03-16
PT101156A (pt) 1994-06-30
IT1252708B (it) 1995-06-26
HUT69287A (en) 1995-09-28
ITMI913448A1 (it) 1993-06-23
CZ379692A3 (en) 1993-09-15
BG98050A (bg) 1994-04-29
NZ245547A (en) 1995-12-21
FI933685A (fi) 1993-08-20
EP0575572A1 (en) 1993-12-29
MX9207543A (es) 1993-08-01
AU3087192A (en) 1993-07-28
HU9302389D0 (en) 1993-11-29

Similar Documents

Publication Publication Date Title
Nishizawa et al. Synthesis and structure-activity relations of bestatin analogs, inhibitors of aminopeptidase B
CN102946726B (zh) 新型降血糖化合物
EP0340064A1 (fr) Benzodiazépines, leur procédé et intermédiaires de préparation et leurs applications en thérapeutique
Krogsgaard-Larsen et al. GABA agonists. Resolution, absolute stereochemistry and enantioselectivity of (S)-(+)-and (R)-(-)-dihydromuscimol
SK379692A3 (en) Stable salts of (+)-(1s,2r)-2-//n-(2-hydroxylamino-2- -oxoethyl)-n-methyl-amino/carbonyl/cyclohexan-1-carboxylic acid, method of their preparation and pharmaceutical agents containing these salts
BRPI1014070B1 (pt) processos para a produção de inibidor de dipeptidil peptidase-iv e intermediário
EP1731501A1 (en) Method of amidocarbonylation reaction
CS197268B2 (en) Process for preparing l-pyroglutamyl-l-histidyl-3-alkylprolinamides
SK13442000A3 (sk) Postup na prípravu tetrapeptidu
JPH09176115A (ja) 光学活性なn−ベンジル−3−アミノピロリジンの製造方法
EP0252030B1 (en) Derivatives of l-amino acyl l-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same
USRE29732E (en) Tripeptide
EP1048674A1 (en) Method for separating and purifying aspartame and aspartame derivative
CN112851536B (zh) 一种利用嘧啶类缩合剂点击构建酰胺键的方法及其在酰胺和多肽合成中的应用
US4975418A (en) Therapeutically active compositions of pseudo-peptide of glutamyl-aspartic acid
EP0101633B1 (en) Pyridinecarboxylic esters of dopamine and of its n-alkyl derivatives
CN109053771B (zh) 一种托法替布的有关物质及其制备方法和应用
CN113045480A (zh) 一种沙格列汀杂环中间体的差向异构体的制备方法
Landvatter Radiolabelled amino acids: Synthesis of NG‐mesitylenesulfonyl‐N2‐[3H] methyl‐arginine
Windridge ANALOGS OF ANGIOTENSIN-II: THEIR SYNTHESIS AND BIOLOGICAL EVALUATION
CZ20003342A3 (cs) Způsob přípravy tetrapeptidu
EP0564587A1 (en) Solution phase process for synthesis of peptide
KR20040072397A (ko) 탐술로신의 정제 방법
Oyama et al. Optical Resolution of Amino Acid Esters by N-Protected Aspartylphenylalanine Esters.
Richards et al. The development of novel methods for the synthesis of histidine-containing peptides