HU9302389D0 - Stable salts of (+)-(1s,2r)-2-(/n-(2-hydroxi-amino-2-oxo-ethyl)-n-metnhyl-amino/-carbonyl/cyclohexane-1-carboxylic acid and method for producing them - Google Patents

Stable salts of (+)-(1s,2r)-2-(/n-(2-hydroxi-amino-2-oxo-ethyl)-n-metnhyl-amino/-carbonyl/cyclohexane-1-carboxylic acid and method for producing them

Info

Publication number
HU9302389D0
HU9302389D0 HU9302389A HU9302389A HU9302389D0 HU 9302389 D0 HU9302389 D0 HU 9302389D0 HU 9302389 A HU9302389 A HU 9302389A HU 9302389 A HU9302389 A HU 9302389A HU 9302389 D0 HU9302389 D0 HU 9302389D0
Authority
HU
Hungary
Prior art keywords
amino
metnhyl
hydroxi
oxo
cyclohexane
Prior art date
Application number
HU9302389A
Other languages
Hungarian (hu)
Other versions
HUT69287A (en
Inventor
Horst Mayer
Gerhard Hamprecht
Helmut Walter
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HU9302389D0 publication Critical patent/HU9302389D0/en
Publication of HUT69287A publication Critical patent/HUT69287A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
HU9302389A 1991-12-23 1992-12-12 Process to prepare stable salts of(+)-(1s,2r)-2-{[n-(2-hydroxylamino-2-oxoethyl)-n-methyl-amino]carbonyl} cyclohexane-1-carboxylic acid and pharmaceutical compns. contg. them HUT69287A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI913448A IT1252708B (en) 1991-12-23 1991-12-23 STABLE SALTS OF (+) - (1R, 2S) -2 ((N- (2-HYDROXYLAMINE-2-OSSOETHL) -N-METHYLAMINE) CARBONYL) CYCLOHEXAN-1-CARBOXYL, ACE INHIBITIVE ACTIVITY, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.

Publications (2)

Publication Number Publication Date
HU9302389D0 true HU9302389D0 (en) 1993-11-29
HUT69287A HUT69287A (en) 1995-09-28

Family

ID=11361409

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9302389A HUT69287A (en) 1991-12-23 1992-12-12 Process to prepare stable salts of(+)-(1s,2r)-2-{[n-(2-hydroxylamino-2-oxoethyl)-n-methyl-amino]carbonyl} cyclohexane-1-carboxylic acid and pharmaceutical compns. contg. them

Country Status (26)

Country Link
EP (1) EP0575572A1 (en)
JP (1) JPH06506002A (en)
CN (1) CN1079474A (en)
AU (1) AU657591B2 (en)
BG (1) BG98050A (en)
BR (1) BR9205652A (en)
CA (1) CA2104372A1 (en)
CZ (1) CZ379692A3 (en)
EE (1) EE9400006A (en)
FI (1) FI933685A0 (en)
HR (1) HRP921454A2 (en)
HU (1) HUT69287A (en)
IT (1) IT1252708B (en)
LV (1) LV10426B (en)
MA (1) MA22749A1 (en)
MX (1) MX9207543A (en)
NZ (1) NZ245547A (en)
PL (1) PL169086B1 (en)
PT (1) PT101156A (en)
RU (1) RU2079489C1 (en)
SI (1) SI9200409A (en)
SK (1) SK379692A3 (en)
TN (1) TNSN92117A1 (en)
WO (1) WO1993013056A1 (en)
YU (1) YU110892A (en)
ZA (1) ZA9210004B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264860B1 (en) * 1993-06-21 1996-10-17 Guidotti & C Spa Labor DERIVATIVES OF CIS- AND TRANS-2(((2-(HYDROXYAMINO)-2-OXOETHYL)- ALKYLAMINO)CARBONYL)CYCLOHEXINECARBOXYLIC ACIDS
US5639746A (en) * 1994-12-29 1997-06-17 The Procter & Gamble Company Hydroxamic acid-containing inhibitors of matrix metalloproteases
FR2817241B1 (en) 2000-11-30 2003-03-07 Cebal ALUMINUM TUBE WITH SPLITABLE END
CA2663614A1 (en) * 2006-09-28 2008-04-10 Merck And Co., Inc. Amine base salts of saha and polymorphs thereof
CA3212302A1 (en) * 2020-04-27 2021-11-04 Carter Hoffmann, Llc Door movement system for cabinet

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224627B (en) * 1988-04-12 1990-10-04 Guidotti & C Spa Labor ACID STARCHES CYCLOMETHYLEN_1,2_DICARBOSSILS THERAPEUTIC ADAPTIVITY, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
HRP921454A2 (en) 1995-02-28
FI933685A (en) 1993-08-20
IT1252708B (en) 1995-06-26
ZA9210004B (en) 1993-12-13
ITMI913448A1 (en) 1993-06-23
FI933685A0 (en) 1993-08-20
EE9400006A (en) 1995-12-15
NZ245547A (en) 1995-12-21
CZ379692A3 (en) 1993-09-15
WO1993013056A1 (en) 1993-07-08
SI9200409A (en) 1993-09-30
BG98050A (en) 1994-04-29
MA22749A1 (en) 1993-07-01
HUT69287A (en) 1995-09-28
YU110892A (en) 1996-01-08
ITMI913448A0 (en) 1991-12-23
SK379692A3 (en) 1995-04-12
RU2079489C1 (en) 1997-05-20
PL169086B1 (en) 1996-05-31
BR9205652A (en) 1994-05-03
PL297118A1 (en) 1993-09-06
EP0575572A1 (en) 1993-12-29
AU3087192A (en) 1993-07-28
CA2104372A1 (en) 1993-06-24
JPH06506002A (en) 1994-07-07
AU657591B2 (en) 1995-03-16
LV10426A (en) 1995-02-20
LV10426B (en) 1995-08-20
TNSN92117A1 (en) 1993-06-08
PT101156A (en) 1994-06-30
CN1079474A (en) 1993-12-15
MX9207543A (en) 1993-08-01

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal