SK286711B6 - Spôsob výroby 13-(N-Boc-beta-izobutylizoserinyl)-14beta- hydroxybakatín III-1,14-karbonátu - Google Patents

Spôsob výroby 13-(N-Boc-beta-izobutylizoserinyl)-14beta- hydroxybakatín III-1,14-karbonátu Download PDF

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Publication number
SK286711B6
SK286711B6 SK642-2003A SK6422003A SK286711B6 SK 286711 B6 SK286711 B6 SK 286711B6 SK 6422003 A SK6422003 A SK 6422003A SK 286711 B6 SK286711 B6 SK 286711B6
Authority
SK
Slovakia
Prior art keywords
carbonate
iii
positions
carried out
process according
Prior art date
Application number
SK642-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK6422003A3 (en
Inventor
Alessandro Pontiroli
Ezio Bombardelli
Original Assignee
Indena S. P. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena S. P. A. filed Critical Indena S. P. A.
Publication of SK6422003A3 publication Critical patent/SK6422003A3/sk
Publication of SK286711B6 publication Critical patent/SK286711B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
SK642-2003A 2000-11-28 2001-11-22 Spôsob výroby 13-(N-Boc-beta-izobutylizoserinyl)-14beta- hydroxybakatín III-1,14-karbonátu SK286711B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI002553A IT1320107B1 (it) 2000-11-28 2000-11-28 Procedimento per la preparazione di derivati tassanici.
PCT/EP2001/013614 WO2002044161A2 (en) 2000-11-28 2001-11-22 A process for the preparation of taxan derivatives

Publications (2)

Publication Number Publication Date
SK6422003A3 SK6422003A3 (en) 2003-11-04
SK286711B6 true SK286711B6 (sk) 2009-03-05

Family

ID=11446144

Family Applications (1)

Application Number Title Priority Date Filing Date
SK642-2003A SK286711B6 (sk) 2000-11-28 2001-11-22 Spôsob výroby 13-(N-Boc-beta-izobutylizoserinyl)-14beta- hydroxybakatín III-1,14-karbonátu

Country Status (24)

Country Link
US (1) US6737534B2 (pt)
EP (1) EP1347984B1 (pt)
JP (1) JP4237490B2 (pt)
KR (1) KR100799393B1 (pt)
CN (1) CN1243005C (pt)
AT (1) ATE275149T1 (pt)
AU (2) AU2956302A (pt)
CA (1) CA2430070C (pt)
CZ (1) CZ300793B6 (pt)
DE (1) DE60105314T2 (pt)
DK (1) DK1347984T3 (pt)
ES (1) ES2227316T3 (pt)
HK (1) HK1059778A1 (pt)
HU (1) HUP0302765A3 (pt)
IL (2) IL156141A0 (pt)
IT (1) IT1320107B1 (pt)
NO (1) NO328143B1 (pt)
PL (1) PL362392A1 (pt)
PT (1) PT1347984E (pt)
RU (1) RU2275365C2 (pt)
SI (1) SI1347984T1 (pt)
SK (1) SK286711B6 (pt)
TR (1) TR200402546T4 (pt)
WO (1) WO2002044161A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
EP1712552A1 (en) * 2005-04-11 2006-10-18 INDENA S.p.A. Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US7232916B1 (en) 2006-05-11 2007-06-19 Indena S.P.A. Process for the preparation of a taxane derivative
EP2080763A1 (en) * 2008-01-18 2009-07-22 INDENA S.p.A. Crystalline form I of ortataxel
ES2389518T3 (es) * 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1275435B (it) 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ITMI991483A1 (it) 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.

Also Published As

Publication number Publication date
NO328143B1 (no) 2009-12-14
CZ20031474A3 (cs) 2003-08-13
SI1347984T1 (en) 2005-02-28
NO20032401L (no) 2003-05-27
US20040030164A1 (en) 2004-02-12
IL156141A0 (en) 2003-12-23
US6737534B2 (en) 2004-05-18
WO2002044161A3 (en) 2002-07-25
PT1347984E (pt) 2004-11-30
TR200402546T4 (tr) 2004-12-21
DE60105314T2 (de) 2005-09-29
JP4237490B2 (ja) 2009-03-11
CA2430070C (en) 2011-09-13
EP1347984B1 (en) 2004-09-01
PL362392A1 (en) 2004-11-02
HUP0302765A3 (en) 2005-02-28
KR20030051864A (ko) 2003-06-25
HK1059778A1 (en) 2004-07-16
IL156141A (en) 2007-02-11
CA2430070A1 (en) 2002-06-06
ITMI20002553A1 (it) 2002-05-28
AU2002229563B2 (en) 2006-03-30
AU2956302A (en) 2002-06-11
SK6422003A3 (en) 2003-11-04
KR100799393B1 (ko) 2008-01-30
HUP0302765A2 (hu) 2003-11-28
RU2275365C2 (ru) 2006-04-27
EP1347984A2 (en) 2003-10-01
WO2002044161A2 (en) 2002-06-06
IT1320107B1 (it) 2003-11-18
DE60105314D1 (de) 2004-10-07
ES2227316T3 (es) 2005-04-01
CN1243005C (zh) 2006-02-22
ATE275149T1 (de) 2004-09-15
CZ300793B6 (cs) 2009-08-12
DK1347984T3 (da) 2005-01-10
CN1478091A (zh) 2004-02-25
JP2004519434A (ja) 2004-07-02
NO20032401D0 (no) 2003-05-27

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AU2002229563A1 (en) A process for the preparation of taxan derivatives
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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101122