SK285623B6 - Spôsob produkcie asialoglykoproteínu hepatitis C vírusu - Google Patents

Spôsob produkcie asialoglykoproteínu hepatitis C vírusu Download PDF

Info

Publication number
SK285623B6
SK285623B6 SK442-93A SK44293A SK285623B6 SK 285623 B6 SK285623 B6 SK 285623B6 SK 44293 A SK44293 A SK 44293A SK 285623 B6 SK285623 B6 SK 285623B6
Authority
SK
Slovakia
Prior art keywords
hcv
asialoglycoprotein
mannose
region
protein
Prior art date
Application number
SK442-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK44293A3 (en
Inventor
Robert O. Ralston
Frank Marcus
Kent B. Thudium
Barbara A. Gervase
Original Assignee
Chiron Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27417050&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK285623(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corporation filed Critical Chiron Corporation
Publication of SK44293A3 publication Critical patent/SK44293A3/sk
Publication of SK285623B6 publication Critical patent/SK285623B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SK442-93A 1990-11-08 1991-11-07 Spôsob produkcie asialoglykoproteínu hepatitis C vírusu SK285623B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61196590A 1990-11-08 1990-11-08
US61141990A 1990-11-08 1990-11-08
US75888091A 1991-09-13 1991-09-13
PCT/US1991/008272 WO1992008734A1 (en) 1990-11-08 1991-11-07 Hepatitis c virus asialoglycoproteins

Publications (2)

Publication Number Publication Date
SK44293A3 SK44293A3 (en) 1993-08-11
SK285623B6 true SK285623B6 (sk) 2007-05-03

Family

ID=27417050

Family Applications (3)

Application Number Title Priority Date Filing Date
SK442-93A SK285623B6 (sk) 1990-11-08 1991-11-07 Spôsob produkcie asialoglykoproteínu hepatitis C vírusu
SK40-2005A SK286106B6 (sk) 1990-11-08 1991-11-07 Spôsob vykonávania imunodiagnostickej skúšky na detekciu protilátky proti vírusu hepatitídy C
SK690-97A SK285624B6 (sk) 1990-11-08 1991-11-07 Hepatitis C vírusový (HCV) skrátený asialoglykoproteín, kompozícia s jeho obsahom a jeho použitie

Family Applications After (2)

Application Number Title Priority Date Filing Date
SK40-2005A SK286106B6 (sk) 1990-11-08 1991-11-07 Spôsob vykonávania imunodiagnostickej skúšky na detekciu protilátky proti vírusu hepatitídy C
SK690-97A SK285624B6 (sk) 1990-11-08 1991-11-07 Hepatitis C vírusový (HCV) skrátený asialoglykoproteín, kompozícia s jeho obsahom a jeho použitie

Country Status (17)

Country Link
EP (2) EP0842947B2 (pt)
JP (8) JPH06504431A (pt)
AT (1) ATE188220T1 (pt)
AU (1) AU668078B2 (pt)
CA (2) CA2095521C (pt)
CZ (1) CZ289006B6 (pt)
DE (1) DE69131882T3 (pt)
DK (2) DK0556292T4 (pt)
ES (1) ES2139591T5 (pt)
FI (1) FI107803B (pt)
GR (1) GR3032771T3 (pt)
HU (2) HUT66063A (pt)
NO (2) NO304380B1 (pt)
PT (2) PT99466B (pt)
RO (1) RO115446B1 (pt)
SK (3) SK285623B6 (pt)
WO (1) WO1992008734A1 (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274148B1 (en) 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
JP3158177B2 (ja) * 1991-10-08 2001-04-23 国立感染症研究所長 C型肝炎診断薬
DE69333269T2 (de) * 1992-01-31 2004-07-29 Abbott Laboratories, Abbott Park Expressionssystem in säugetieren für hcv-proteine
UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
JPH08510240A (ja) 1993-05-12 1996-10-29 カイロン コーポレイション C型肝炎ウイルスe2/ns1領域の保存モチーフ
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5610009A (en) * 1994-01-28 1997-03-11 Abbott Laboratories Mammalian expression systems for hepatitis C virus envelope genes
ES2316920T3 (es) 1994-07-29 2009-04-16 Novartis Vaccines And Diagnostics, Inc. Popipeptido truncado e2 de hepatitis c y procedimientos para obtener el mismo.
JPH09503396A (ja) 1994-07-29 1997-04-08 インノジェネティクス・エヌ・ブイ 診断用及び治療用の精製c型肝炎ウイルスエンベロープ蛋白
PT773957E (pt) * 1994-07-29 2005-11-30 Chiron Corp Polipeptidos truncados e1 e e2 de hepatite c inovadores, e metodos de obtencao dos mesmos
IT1271593B (it) * 1994-11-30 1997-06-04 Sanitaria Scaligera Spa Procedimento ed apparecchiatura per l'immunoadsorbimento specifico di virus hiv, di antigene gp120 e complesso cd4-gp120.
US6127116A (en) 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
FR2744725B1 (fr) * 1996-02-09 1998-04-30 Pasteur Institut Anticorps specifiques des complexes formes par les glycoproteines e1 et e2 du virus de l'hepatite c, procedes de determination de la presence, et d'isolement de ces complexes
US6514731B1 (en) 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
KR100209095B1 (ko) 1996-06-28 1999-07-15 성재갑 C형 간염 바이러스의 프로테아제의 활성을 측정할 수 있는 c형 간염 대체 바이러스, 그 재조합 유전자 및 그 용도
CA2269097C (en) 1996-11-08 2007-01-09 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Synthesis and purification of hepatitis c virus-like particles
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
EP0980434B1 (en) 1997-05-06 2009-07-29 Novartis Vaccines and Diagnostics, Inc. Intracellular production of hepatitis c e2 truncated polypeptid
EP0947525A1 (en) 1998-03-27 1999-10-06 Innogenetics N.V. Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue
US7108855B2 (en) 1998-06-24 2006-09-19 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
WO2002014362A2 (en) 2000-08-17 2002-02-21 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7101561B2 (en) 2000-12-01 2006-09-05 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
US20030232745A1 (en) * 2001-06-26 2003-12-18 Olson William C. Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection
US7022323B2 (en) 2001-06-26 2006-04-04 Progenics Pharmaceuticals, Inc. Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection
AU2003265454A1 (en) * 2002-08-16 2004-03-03 Ohio University Hepatitis c viral-like particle purification
CA2618429A1 (en) 2005-05-25 2007-03-22 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform
WO2009130588A2 (en) 2008-04-22 2009-10-29 Tripep Ab Immunogen platform

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ227011A (en) * 1987-11-18 1992-03-26 Chiron Corp Non-a, non-b-hepatitis (hepatitis c) antigens, proteins, nucleotide sequences, vaccines and kits
IL88599A0 (en) * 1987-12-10 1989-07-31 Cell Bio Group Ltd Glycoprotein cell growth modulating materials,their preparation and compositions containing them
HUT54896A (en) * 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
HU217025B (hu) * 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben

Also Published As

Publication number Publication date
EP0842947B2 (en) 2009-03-18
EP0556292B2 (en) 2006-11-29
ES2139591T5 (es) 2007-08-01
JP4056306B2 (ja) 2008-03-05
JP2001286290A (ja) 2001-10-16
CA2203443A1 (en) 1992-05-09
CA2203443C (en) 2001-08-28
SK285624B6 (sk) 2007-05-03
GR3032771T3 (en) 2000-06-30
EP0556292B1 (en) 1999-12-29
DE69131882D1 (en) 2000-02-03
PT102022B (pt) 2000-12-29
FI107803B (fi) 2001-10-15
NO972213D0 (no) 1997-05-14
CZ289006B6 (cs) 2001-10-17
JP3207155B2 (ja) 2001-09-10
PT99466B (pt) 1999-04-30
NO304381B1 (no) 1998-12-07
HU9301336D0 (en) 1993-10-28
EP0556292A4 (pt) 1995-01-18
JPH06504431A (ja) 1994-05-26
SK69097A3 (en) 1997-11-05
CA2095521A1 (en) 1992-05-09
DK0842947T3 (da) 2004-07-26
ATE188220T1 (de) 2000-01-15
EP0842947A3 (en) 2001-12-12
JP2008031181A (ja) 2008-02-14
PT99466A (pt) 1992-10-30
JP2003174875A (ja) 2003-06-24
DK0556292T4 (da) 2006-12-27
SK286106B6 (sk) 2008-03-05
ES2139591T3 (es) 2000-02-16
EP0842947B1 (en) 2004-04-21
WO1992008734A1 (en) 1992-05-29
NO304380B1 (no) 1998-12-07
DE69131882T2 (de) 2000-05-04
FI932025A0 (fi) 1993-05-05
DK0556292T3 (da) 2000-04-17
SK44293A3 (en) 1993-08-11
NO972213L (no) 1997-05-14
JPH1171395A (ja) 1999-03-16
DE69131882T3 (de) 2007-05-24
CZ82493A3 (en) 1994-04-13
DK0842947T4 (da) 2009-06-08
PT102022A (pt) 1999-01-29
FI932025A (fi) 1993-06-07
JP2005187479A (ja) 2005-07-14
CA2095521C (en) 2009-06-30
HUT66063A (en) 1994-09-28
AU668078B2 (en) 1996-04-26
NO931680L (no) 1993-06-28
RO115446B1 (ro) 2000-02-28
EP0556292A1 (en) 1993-08-25
NO931680D0 (no) 1993-05-07
JP2006219503A (ja) 2006-08-24
HU227498B1 (en) 2011-07-28
EP0842947A2 (en) 1998-05-20
AU9026791A (en) 1992-06-11
JP2003093081A (ja) 2003-04-02

Similar Documents

Publication Publication Date Title
SK285623B6 (sk) Spôsob produkcie asialoglykoproteínu hepatitis C vírusu
US7105303B2 (en) Antibodies to hepatitis C virus asialoglycoproteins
RU2175657C2 (ru) Асиалогликопротеин вируса гепатита c (нсv), иммуногенная композиция, способ индукции иммунного ответа, способ иммуноанализа
EP1471073B1 (en) Hepatitis C virus asialoglycoproteins
FI107804B (fi) Immunomäärityksissä käytettäviä hepatiitti-C-viruksen asialoglykoproteiineja
JP2945759B2 (ja) C型肝炎ウイルスアシアロ糖タンパク質
CZ289923B6 (cs) Hepatitis C virový, zkrácený asialoglykoprotein, farmaceutická kompozice s jeho obsahem a jeho pouľití
IE84479B1 (en) Hepatitis C Virus Asialoglycoproteins

Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20111107