SK285619B6 - Aminoalkylsubstituovaný benzopyránový derivát, spôsob jeho prípravy, farmaceutický prostriedok a spôsob jeho prípravy - Google Patents

Aminoalkylsubstituovaný benzopyránový derivát, spôsob jeho prípravy, farmaceutický prostriedok a spôsob jeho prípravy Download PDF

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Publication number
SK285619B6
SK285619B6 SK1703-2001A SK17032001A SK285619B6 SK 285619 B6 SK285619 B6 SK 285619B6 SK 17032001 A SK17032001 A SK 17032001A SK 285619 B6 SK285619 B6 SK 285619B6
Authority
SK
Slovakia
Prior art keywords
formula
hydrogen
alk
compound
group
Prior art date
Application number
SK1703-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK17032001A3 (sk
Inventor
Emelen Kristof Van
Bruyn Marcel Frans Leopold De
Original Assignee
Janssen Pharmaceutica N. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N. V. filed Critical Janssen Pharmaceutica N. V.
Publication of SK17032001A3 publication Critical patent/SK17032001A3/sk
Publication of SK285619B6 publication Critical patent/SK285619B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
SK1703-2001A 1999-06-02 2000-05-23 Aminoalkylsubstituovaný benzopyránový derivát, spôsob jeho prípravy, farmaceutický prostriedok a spôsob jeho prípravy SK285619B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99201747 1999-06-02
PCT/EP2000/004746 WO2000075136A1 (en) 1999-06-02 2000-05-23 Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives

Publications (2)

Publication Number Publication Date
SK17032001A3 SK17032001A3 (sk) 2002-07-02
SK285619B6 true SK285619B6 (sk) 2007-05-03

Family

ID=8240260

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1703-2001A SK285619B6 (sk) 1999-06-02 2000-05-23 Aminoalkylsubstituovaný benzopyránový derivát, spôsob jeho prípravy, farmaceutický prostriedok a spôsob jeho prípravy

Country Status (33)

Country Link
US (2) US6864273B1 (et)
EP (1) EP1187829B1 (et)
JP (1) JP2003501427A (et)
KR (1) KR100699512B1 (et)
CN (1) CN1150191C (et)
AR (1) AR033334A1 (et)
AT (1) ATE256125T1 (et)
AU (1) AU773773B2 (et)
BG (1) BG65269B1 (et)
BR (1) BR0011237A (et)
CA (1) CA2374902C (et)
CZ (1) CZ20014177A3 (et)
DE (1) DE60007124T2 (et)
DK (1) DK1187829T3 (et)
EA (1) EA004645B1 (et)
EE (1) EE04780B1 (et)
ES (1) ES2212774T3 (et)
HR (1) HRP20010868A2 (et)
HU (1) HUP0201404A3 (et)
IL (2) IL146840A0 (et)
MX (1) MXPA01012330A (et)
MY (1) MY120618A (et)
NO (1) NO319953B1 (et)
NZ (1) NZ514993A (et)
PL (1) PL198552B1 (et)
PT (1) PT1187829E (et)
SI (1) SI1187829T1 (et)
SK (1) SK285619B6 (et)
TR (1) TR200103430T2 (et)
TW (1) TWI289559B (et)
UA (1) UA73122C2 (et)
WO (1) WO2000075136A1 (et)
ZA (1) ZA200109860B (et)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL198532B1 (pl) 1999-06-02 2008-06-30 Janssen Pharmaceutica Nv Pochodna benzopiranu podstawiona pirolidynylem, piperydynylem lub homopiperydynylem i sposób jej otrzymywania oraz kompozycja farmaceutyczna i sposób jej otrzymywania
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
KR20120037035A (ko) * 2002-04-08 2012-04-18 제리아 신야쿠 고교 가부시키 가이샤 위 음식물 수용능 장해 치료약
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
JP5731718B2 (ja) 2011-11-11 2015-06-10 ファイザー・インク ２−チオピリミジノン
MA42035A (fr) 2015-05-05 2018-03-14 Pfizer 2-thiopyrimidinones

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (et) 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
CN1052006C (zh) 1993-08-19 2000-05-03 詹森药业有限公司 血管收缩剂二氢苯并吡喃衍生物,制备方法和用途
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
PL198532B1 (pl) 1999-06-02 2008-06-30 Janssen Pharmaceutica Nv Pochodna benzopiranu podstawiona pirolidynylem, piperydynylem lub homopiperydynylem i sposób jej otrzymywania oraz kompozycja farmaceutyczna i sposób jej otrzymywania
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
DE60007124T2 (de) 2004-09-23
KR20010110806A (ko) 2001-12-13
CA2374902A1 (en) 2000-12-14
EE200100639A (et) 2003-02-17
ES2212774T3 (es) 2004-08-01
AU5525600A (en) 2000-12-28
PL352112A1 (en) 2003-07-28
CZ20014177A3 (cs) 2002-05-15
NZ514993A (en) 2003-05-30
DE60007124D1 (de) 2004-01-22
US7273862B2 (en) 2007-09-25
MY120618A (en) 2005-11-30
EA200101236A1 (ru) 2002-08-29
TWI289559B (en) 2007-11-11
ZA200109860B (en) 2003-05-28
NO20015903D0 (no) 2001-12-03
CN1353707A (zh) 2002-06-12
ATE256125T1 (de) 2003-12-15
PL198552B1 (pl) 2008-06-30
EE04780B1 (et) 2007-02-15
EP1187829B1 (en) 2003-12-10
UA73122C2 (en) 2005-06-15
EP1187829A1 (en) 2002-03-20
MXPA01012330A (es) 2002-07-30
HUP0201404A2 (en) 2002-08-28
SI1187829T1 (en) 2004-04-30
US6864273B1 (en) 2005-03-08
NO20015903L (no) 2001-12-03
JP2003501427A (ja) 2003-01-14
IL146840A (en) 2006-12-10
KR100699512B1 (ko) 2007-03-26
HUP0201404A3 (en) 2005-02-28
PT1187829E (pt) 2004-04-30
TR200103430T2 (tr) 2002-06-21
CN1150191C (zh) 2004-05-19
AR033334A1 (es) 2003-12-17
EA004645B1 (ru) 2004-06-24
BR0011237A (pt) 2002-03-05
WO2000075136A1 (en) 2000-12-14
BG106156A (en) 2002-05-31
IL146840A0 (en) 2002-07-25
BG65269B1 (bg) 2007-11-30
SK17032001A3 (sk) 2002-07-02
CA2374902C (en) 2009-09-15
DK1187829T3 (da) 2004-04-13
AU773773B2 (en) 2004-06-03
HRP20010868A2 (en) 2003-04-30
US20050096378A1 (en) 2005-05-05
NO319953B1 (no) 2005-10-03

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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100523