SK285438B6 - Spôsob prípravy (1H)-benzo[c]chinolizín-3-ových derivátov - Google Patents

Spôsob prípravy (1H)-benzo[c]chinolizín-3-ových derivátov Download PDF

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Publication number
SK285438B6
SK285438B6 SK167-2001A SK1672001A SK285438B6 SK 285438 B6 SK285438 B6 SK 285438B6 SK 1672001 A SK1672001 A SK 1672001A SK 285438 B6 SK285438 B6 SK 285438B6
Authority
SK
Slovakia
Prior art keywords
benzo
tetrahydro
quinolizin
dimethyl
chloro
Prior art date
Application number
SK167-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK1672001A3 (en
Inventor
Antonio Guarna
Mario Serio
Ernesto Giovanni Occhiato
Original Assignee
Applied Research Systems Ars Holding N. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N. V. filed Critical Applied Research Systems Ars Holding N. V.
Publication of SK1672001A3 publication Critical patent/SK1672001A3/sk
Publication of SK285438B6 publication Critical patent/SK285438B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK167-2001A 1998-08-03 1999-07-23 Spôsob prípravy (1H)-benzo[c]chinolizín-3-ových derivátov SK285438B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98114524 1998-08-03
PCT/EP1999/005277 WO2000008019A1 (en) 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives

Publications (2)

Publication Number Publication Date
SK1672001A3 SK1672001A3 (en) 2001-08-06
SK285438B6 true SK285438B6 (sk) 2007-01-04

Family

ID=8232396

Family Applications (1)

Application Number Title Priority Date Filing Date
SK167-2001A SK285438B6 (sk) 1998-08-03 1999-07-23 Spôsob prípravy (1H)-benzo[c]chinolizín-3-ových derivátov

Country Status (29)

Country Link
US (1) US6723850B1 (zh)
EP (1) EP1102765B1 (zh)
JP (1) JP2002522435A (zh)
KR (1) KR100624239B1 (zh)
CN (1) CN1128148C (zh)
AT (1) ATE250057T1 (zh)
AU (1) AU751873B2 (zh)
BG (1) BG65062B1 (zh)
BR (1) BR9912870A (zh)
CA (1) CA2338498C (zh)
CZ (1) CZ291648B6 (zh)
DE (1) DE69911430T2 (zh)
DK (1) DK1102765T3 (zh)
EA (1) EA003997B1 (zh)
EE (1) EE04642B1 (zh)
ES (1) ES2203169T3 (zh)
HK (1) HK1037368A1 (zh)
HU (1) HUP0103241A3 (zh)
IL (2) IL141212A0 (zh)
NO (1) NO20010559D0 (zh)
NZ (1) NZ509243A (zh)
PL (1) PL198963B1 (zh)
PT (1) PT1102765E (zh)
SI (1) SI1102765T1 (zh)
SK (1) SK285438B6 (zh)
TR (1) TR200100286T2 (zh)
UA (1) UA67787C2 (zh)
WO (1) WO2000008019A1 (zh)
ZA (1) ZA200100365B (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
DK1773816T3 (en) 2004-06-24 2015-01-26 Vertex Pharma Modulators of ATP-binding cassette transporters
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
US20090105272A1 (en) * 2005-12-24 2009-04-23 Grootenhuis Peter D J Prodrugs of modulators of ABC transporters
JP5409010B2 (ja) 2005-12-28 2014-02-05 バーテックス ファーマシューティカルズ インコーポレイテッド N−[2,4−ビス(1,1−ジメチルエチル)−5−ヒドロキシフェニル]−1,4−ジヒドロ−4−オキソキノリン−3−カルボキサミドの固体形態
NZ624460A (en) 2009-03-20 2015-12-24 Vertex Pharma Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
JP5918256B2 (ja) * 2010-12-14 2016-05-18 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト ストリゴラクタム誘導体および植物成長調節剤としてのこれらの使用
CN104470518A (zh) 2012-02-27 2015-03-25 沃泰克斯药物股份有限公司 药物组合物及其施用
CA2963945C (en) 2014-10-07 2023-01-10 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
CN105001216B (zh) * 2015-07-08 2017-03-01 中国科学院兰州化学物理研究所 一种喹嗪酮的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064961A (en) * 1989-12-18 1991-11-12 E. R. Squibb & Sons, Inc. Process for preparing an optically active cyclobutane nucleoside
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
IT1286545B1 (it) * 1996-02-09 1998-07-15 Antonio Guarna Derivati benzo(c) chinolizinici,loro preparazione ed uso come inibitori delle 5-alfa-riduttasi
JPH09316076A (ja) * 1996-05-24 1997-12-09 Nippon Paper Ind Co Ltd 9−置換プリン誘導体及びその抗ウイルス剤としての用途

Also Published As

Publication number Publication date
ZA200100365B (en) 2001-07-26
WO2000008019A1 (en) 2000-02-17
TR200100286T2 (tr) 2001-07-23
DE69911430D1 (de) 2003-10-23
EP1102765A1 (en) 2001-05-30
CZ2001434A3 (cs) 2001-08-15
UA67787C2 (uk) 2004-07-15
US6723850B1 (en) 2004-04-20
EE200100060A (et) 2002-06-17
AU6312399A (en) 2000-02-28
ATE250057T1 (de) 2003-10-15
JP2002522435A (ja) 2002-07-23
EE04642B1 (et) 2006-06-15
CZ291648B6 (cs) 2003-04-16
BR9912870A (pt) 2001-10-16
DE69911430T2 (de) 2004-07-22
PT1102765E (pt) 2003-12-31
EA200100213A1 (ru) 2001-08-27
HUP0103241A3 (en) 2002-10-28
ES2203169T3 (es) 2004-04-01
CA2338498C (en) 2009-05-19
KR100624239B1 (ko) 2006-09-13
KR20010074684A (ko) 2001-08-09
BG105198A (en) 2001-12-29
EA003997B1 (ru) 2003-12-25
IL141212A (en) 2006-12-31
CN1128148C (zh) 2003-11-19
PL198963B1 (pl) 2008-08-29
NO20010559L (no) 2001-02-01
NZ509243A (en) 2002-11-26
PL345802A1 (en) 2002-01-02
BG65062B1 (bg) 2007-01-31
SI1102765T1 (en) 2003-12-31
IL141212A0 (en) 2002-03-10
AU751873B2 (en) 2002-08-29
DK1102765T3 (da) 2004-02-02
HUP0103241A2 (hu) 2002-01-28
CN1311788A (zh) 2001-09-05
EP1102765B1 (en) 2003-09-17
HK1037368A1 (en) 2002-02-08
SK1672001A3 (en) 2001-08-06
NO20010559D0 (no) 2001-02-01
CA2338498A1 (en) 2000-02-17

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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100723