SK285280B6 - Inhibítor VLA-4, farmaceutická kompozícia a ich použitie na prípravu liečiva - Google Patents
Inhibítor VLA-4, farmaceutická kompozícia a ich použitie na prípravu liečiva Download PDFInfo
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- SK285280B6 SK285280B6 SK1810-2000A SK18102000A SK285280B6 SK 285280 B6 SK285280 B6 SK 285280B6 SK 18102000 A SK18102000 A SK 18102000A SK 285280 B6 SK285280 B6 SK 285280B6
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- omepupa
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Classifications
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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Landscapes
- Health & Medical Sciences (AREA)
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- Emergency Medicine (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8706498P | 1998-05-28 | 1998-05-28 | |
| PCT/US1999/011924 WO1999061421A1 (en) | 1998-05-28 | 1999-05-28 | A NOVEL VLA-4 INHIBITOR: oMePUPA-V |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK18102000A3 SK18102000A3 (sk) | 2001-07-10 |
| SK285280B6 true SK285280B6 (sk) | 2006-10-05 |
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| SK1810-2000A SK285280B6 (sk) | 1998-05-28 | 1999-05-28 | Inhibítor VLA-4, farmaceutická kompozícia a ich použitie na prípravu liečiva |
Country Status (31)
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| EP (1) | EP1082302B1 (es) |
| JP (1) | JP2002516309A (es) |
| KR (1) | KR100636713B1 (es) |
| CN (1) | CN1148350C (es) |
| AT (1) | ATE256659T1 (es) |
| AU (1) | AU764108B2 (es) |
| BG (1) | BG65021B1 (es) |
| CA (1) | CA2333656C (es) |
| CZ (1) | CZ298413B6 (es) |
| DE (1) | DE69913687T2 (es) |
| DK (1) | DK1082302T3 (es) |
| EA (1) | EA002988B1 (es) |
| EE (1) | EE04639B1 (es) |
| ES (1) | ES2211096T3 (es) |
| HK (1) | HK1035726A1 (es) |
| HU (1) | HUP0102255A3 (es) |
| IL (1) | IL139967A (es) |
| IS (1) | IS5737A (es) |
| MX (1) | MXPA00011774A (es) |
| NO (1) | NO317990B1 (es) |
| NZ (1) | NZ509199A (es) |
| PL (1) | PL198189B1 (es) |
| PT (1) | PT1082302E (es) |
| SI (1) | SI1082302T1 (es) |
| SK (1) | SK285280B6 (es) |
| TR (1) | TR200100190T2 (es) |
| UA (1) | UA65623C2 (es) |
| WO (1) | WO1999061421A1 (es) |
| YU (1) | YU75500A (es) |
| ZA (1) | ZA200007300B (es) |
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| US6645939B1 (en) | 1997-11-24 | 2003-11-11 | Merck & Co., Inc. | Substituted β-alanine derivatives as cell adhesion inhibitors |
| JP2001524465A (ja) * | 1997-11-24 | 2001-12-04 | メルク エンド カムパニー インコーポレーテッド | 細胞接着阻害剤としての置換β−アラニン誘導体 |
| AU757873B2 (en) * | 1998-09-14 | 2003-03-06 | Board Of Regents, The University Of Texas System | Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists |
| US7618630B2 (en) | 1998-09-14 | 2009-11-17 | Board Of Regents, The University Of Texas System | Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists |
| US6525069B1 (en) | 1998-12-18 | 2003-02-25 | Bristol-Myers Squibb Pharma Co. | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
| CZ2002518A3 (cs) | 1999-08-13 | 2002-05-15 | Biogen, Inc. | Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují |
| NZ518886A (en) | 1999-12-28 | 2004-02-27 | Pfizer Prod Inc | Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases |
| WO2002053534A1 (fr) | 2000-12-28 | 2002-07-11 | Daiichi Pharmaceutical Co., Ltd. | Inhibiteurs de vla-4 |
| ES2382806T3 (es) | 2003-07-24 | 2012-06-13 | Daiichi Sankyo Company, Limited | Compuesto ácido ciclohexanocarboxílico |
| US7419666B1 (en) | 2004-02-23 | 2008-09-02 | Massachusetts Eye And Ear Infirmary | Treatment of ocular disorders |
| US7196112B2 (en) | 2004-07-16 | 2007-03-27 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
| GT200500321A (es) * | 2004-11-09 | 2006-09-04 | Compuestos y composiciones como inhibidores de proteina kinase. | |
| US7685367B2 (en) * | 2006-03-08 | 2010-03-23 | Microsoft Corporation | Multi-cache cooperation for response output caching |
| MX2009001272A (es) * | 2006-08-02 | 2009-02-11 | Genzyme Corp | Terapia de combinacion. |
| CA2714335A1 (en) | 2007-02-20 | 2008-08-28 | Merrimack Pharmaceuticals, Inc. | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
| CN102057054B (zh) | 2008-04-11 | 2015-06-10 | 梅里麦克制药股份有限公司 | 人血清白蛋白接头以及其结合物 |
| CN102282168A (zh) | 2008-11-18 | 2011-12-14 | 梅里麦克制药股份有限公司 | 人血清白蛋白接头以及其结合物 |
| EP3466977B1 (en) | 2010-04-16 | 2022-01-05 | Biogen MA Inc. | Anti-vla-4 antibodies |
| US20150202287A1 (en) | 2012-08-30 | 2015-07-23 | Merrimack Pharmaceuticals, Inc. | Combination therapies comprising anti-erbb3 agents |
| US11174256B2 (en) | 2018-10-30 | 2021-11-16 | Gilead Sciences, Inc. | Imidazopyridine derivatives |
| AU2019373242B2 (en) | 2018-10-30 | 2023-07-13 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| WO2020092401A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN |
| CN112969687A (zh) | 2018-10-30 | 2021-06-15 | 吉利德科学公司 | 作为α4β7整合素抑制剂的喹啉衍生物 |
| CA3148613A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Phenylalanine derived compounds and their use as inhinitors of alpha 4 beta 7 integrin |
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| IT1149971B (it) | 1979-06-11 | 1986-12-10 | Syntex Inc | Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante |
| US4725583A (en) | 1985-01-23 | 1988-02-16 | Abbott Laboratories | Functionalized peptidylaminoalcohols |
| US4826815A (en) | 1985-05-17 | 1989-05-02 | Abbott Laboratories | Renin inhibiting compounds |
| DK163689A (da) | 1988-04-08 | 1989-10-30 | Sandoz Ag | Peptidderivater |
| DK0506748T3 (da) | 1989-12-22 | 1996-01-22 | Commw Scient Ind Res Org | Aminosyrer, peptider eller derivater deraf bundet til fedtstoffer |
| CA2043741C (en) | 1990-06-07 | 2003-04-01 | Kiyofumi Ishikawa | Endothelin antagonistic peptide derivatives |
| US5192746A (en) | 1990-07-09 | 1993-03-09 | Tanabe Seiyaku Co., Ltd. | Cyclic cell adhesion modulation compounds |
| US5260277A (en) * | 1990-09-10 | 1993-11-09 | Tanabe Seiyaku Co., Ltd. | Guanidinyl and related cell adhesion modulation compounds |
| WO1992008464A1 (en) | 1990-11-15 | 1992-05-29 | Tanabe Seiyaku Co. Ltd. | Substituted urea and related cell adhesion modulation compounds |
| DE69226820T2 (de) | 1991-06-21 | 1999-05-12 | Merck & Co Inc | Peptidylderivate als Inhibitoren von Interleukin-1B-konvertierenden Enzymen |
| WO1993008823A1 (en) | 1991-11-06 | 1993-05-13 | Tanabe Seiyaku Co., Ltd. | Guanidinyl and related cell adhesion modulation compounds |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20090528 |