SK285046B6 - Chimérna protilátka, ktorá sa špecificky viaže na ľudský antigén, farmaceutický prostriedok s jej obsahom, spôsob jej výroby a použitie - Google Patents

Chimérna protilátka, ktorá sa špecificky viaže na ľudský antigén, farmaceutický prostriedok s jej obsahom, spôsob jej výroby a použitie Download PDF

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Publication number
SK285046B6
SK285046B6 SK88-94A SK8894A SK285046B6 SK 285046 B6 SK285046 B6 SK 285046B6 SK 8894 A SK8894 A SK 8894A SK 285046 B6 SK285046 B6 SK 285046B6
Authority
SK
Slovakia
Prior art keywords
human
antibody
chimeric antibody
nucleic acid
monkey
Prior art date
Application number
SK88-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK8894A3 (en
Inventor
Roland A. Newman
Nabil Hanna
Ronald W. Raab
Original Assignee
Idec Pharmaceuticals Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27112830&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK285046(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Idec Pharmaceuticals Corporation filed Critical Idec Pharmaceuticals Corporation
Publication of SK8894A3 publication Critical patent/SK8894A3/sk
Publication of SK285046B6 publication Critical patent/SK285046B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SK88-94A 1991-07-25 1992-07-24 Chimérna protilátka, ktorá sa špecificky viaže na ľudský antigén, farmaceutický prostriedok s jej obsahom, spôsob jej výroby a použitie SK285046B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73506491A 1991-07-25 1991-07-25
US85628192A 1992-03-23 1992-03-23
PCT/US1992/006194 WO1993002108A1 (en) 1991-07-25 1992-07-24 Recombinant antibodies for human therapy

Publications (2)

Publication Number Publication Date
SK8894A3 SK8894A3 (en) 1994-09-07
SK285046B6 true SK285046B6 (sk) 2006-05-04

Family

ID=27112830

Family Applications (2)

Application Number Title Priority Date Filing Date
SK88-94A SK285046B6 (sk) 1991-07-25 1992-07-24 Chimérna protilátka, ktorá sa špecificky viaže na ľudský antigén, farmaceutický prostriedok s jej obsahom, spôsob jej výroby a použitie
SK5059-2005A SK285960B6 (sk) 1991-07-25 1992-07-24 Rekombinantné protilátky na liečenie ľudí

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK5059-2005A SK285960B6 (sk) 1991-07-25 1992-07-24 Rekombinantné protilátky na liečenie ľudí

Country Status (24)

Country Link
EP (3) EP1266965B1 (pt)
JP (1) JP3048640B2 (pt)
KR (1) KR0137806B1 (pt)
AP (1) AP307A (pt)
AT (2) ATE237638T1 (pt)
AU (1) AU673499B2 (pt)
BG (1) BG62656B1 (pt)
BR (1) BR9206313A (pt)
CA (1) CA2114015C (pt)
CZ (1) CZ289472B6 (pt)
DE (2) DE69233628T2 (pt)
DK (2) DK0605442T3 (pt)
ES (2) ES2265005T3 (pt)
FI (1) FI117703B (pt)
HU (2) HUT70272A (pt)
IL (1) IL102640A0 (pt)
MY (1) MY121185A (pt)
NO (1) NO318097B1 (pt)
NZ (1) NZ243706A (pt)
OA (1) OA09879A (pt)
PT (1) PT100735B (pt)
RO (1) RO116404B1 (pt)
SK (2) SK285046B6 (pt)
WO (1) WO1993002108A1 (pt)

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US5919452A (en) * 1991-03-18 1999-07-06 New York University Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
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US7744877B2 (en) 1992-11-13 2010-06-29 Biogen Idec Inc. Expression and use of anti-CD20 Antibodies
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662752B2 (en) * 1991-07-15 1995-09-14 Wellcome Foundation Limited, The Production of antibodies

Also Published As

Publication number Publication date
IL102640A0 (en) 1993-01-14
AU2425592A (en) 1993-02-23
EP1266965B1 (en) 2006-05-24
CA2114015A1 (en) 1993-02-04
FI117703B (fi) 2007-01-31
NO940219D0 (no) 1994-01-21
DE69233628T2 (de) 2007-04-26
HU211881A9 (en) 1995-12-28
JPH06509708A (ja) 1994-11-02
SK285960B6 (sk) 2007-12-06
ES2196002T3 (es) 2003-12-16
AP307A (en) 1994-01-31
DK0605442T3 (da) 2003-08-04
HUT70272A (en) 1995-09-28
SK8894A3 (en) 1994-09-07
DE69233011T2 (de) 2003-11-06
EP0605442B1 (en) 2003-04-16
CA2114015C (en) 2002-12-10
MY121185A (en) 2006-01-28
FI940336A (fi) 1994-03-10
CZ14994A3 (en) 1994-07-13
ATE327331T1 (de) 2006-06-15
OA09879A (en) 1994-09-15
BG62656B1 (bg) 2000-04-28
ES2265005T3 (es) 2007-02-01
PT100735A (pt) 1993-10-29
PT100735B (pt) 1999-07-30
ATE237638T1 (de) 2003-05-15
DK1266965T3 (da) 2006-09-25
NO940219L (no) 1994-03-25
NO318097B1 (no) 2005-01-31
WO1993002108A1 (en) 1993-02-04
CZ289472B6 (cs) 2002-01-16
EP0605442A1 (en) 1994-07-13
EP1266965A3 (en) 2003-01-02
BR9206313A (pt) 1995-04-11
KR0137806B1 (ko) 1998-04-30
EP1715045A3 (en) 2006-12-13
AP9200413A0 (en) 1992-07-31
EP1266965A2 (en) 2002-12-18
FI940336A0 (fi) 1994-01-24
DE69233011D1 (de) 2003-05-22
HU9400201D0 (en) 1994-05-30
DE69233628D1 (de) 2006-06-29
BG98411A (bg) 1995-02-28
JP3048640B2 (ja) 2000-06-05
AU673499B2 (en) 1996-11-14
EP0605442A4 (en) 1995-07-12
NZ243706A (en) 1994-08-26
RO116404B1 (ro) 2001-01-30
EP1715045A2 (en) 2006-10-25

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