SK283597B6 - Farmaceutický prípravok na orálne podanie, spôsob jeho prípravy a jeho použitie, farmaceutický produkt a súprava - Google Patents

Farmaceutický prípravok na orálne podanie, spôsob jeho prípravy a jeho použitie, farmaceutický produkt a súprava Download PDF

Info

Publication number
SK283597B6
SK283597B6 SK191-98A SK19198A SK283597B6 SK 283597 B6 SK283597 B6 SK 283597B6 SK 19198 A SK19198 A SK 19198A SK 283597 B6 SK283597 B6 SK 283597B6
Authority
SK
Slovakia
Prior art keywords
administration
pharmaceutical
active ingredient
apomorphine
pharmaceutical composition
Prior art date
Application number
SK191-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK19198A3 (en
Inventor
Edward Stewart Johnson
Anthony Clarke
Richard David Green
Original Assignee
R.P. Scherer Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R.P. Scherer Limited filed Critical R.P. Scherer Limited
Publication of SK19198A3 publication Critical patent/SK19198A3/sk
Publication of SK283597B6 publication Critical patent/SK283597B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SK191-98A 1995-08-18 1996-08-16 Farmaceutický prípravok na orálne podanie, spôsob jeho prípravy a jeho použitie, farmaceutický produkt a súprava SK283597B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9517062.7A GB9517062D0 (en) 1995-08-18 1995-08-18 Pharmaceutical compositions
PCT/GB1996/002020 WO1997006786A1 (en) 1995-08-18 1996-08-16 Oral fast-dissolving compositions for dopamine agonists

Publications (2)

Publication Number Publication Date
SK19198A3 SK19198A3 (en) 1998-09-09
SK283597B6 true SK283597B6 (sk) 2003-10-07

Family

ID=10779521

Family Applications (1)

Application Number Title Priority Date Filing Date
SK191-98A SK283597B6 (sk) 1995-08-18 1996-08-16 Farmaceutický prípravok na orálne podanie, spôsob jeho prípravy a jeho použitie, farmaceutický produkt a súprava

Country Status (27)

Country Link
US (1) US6316027B1 (cs)
EP (1) EP0850050B1 (cs)
JP (1) JPH11511162A (cs)
AT (1) ATE196249T1 (cs)
AU (1) AU709641B2 (cs)
BG (1) BG63188B1 (cs)
BR (1) BR9610424A (cs)
CA (1) CA2229597C (cs)
CZ (1) CZ293129B6 (cs)
DE (1) DE69610323T2 (cs)
DK (1) DK0850050T3 (cs)
EE (1) EE03471B1 (cs)
ES (1) ES2151672T3 (cs)
GB (1) GB9517062D0 (cs)
GR (1) GR3034583T3 (cs)
HU (1) HU222197B1 (cs)
MX (1) MX9801305A (cs)
NO (1) NO313368B1 (cs)
NZ (1) NZ315740A (cs)
PL (1) PL187718B1 (cs)
PT (1) PT850050E (cs)
RO (1) RO119066B1 (cs)
RU (1) RU2189226C2 (cs)
SK (1) SK283597B6 (cs)
UA (1) UA64700C2 (cs)
WO (1) WO1997006786A1 (cs)
ZA (1) ZA967032B (cs)

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121276A (en) * 1994-04-22 2000-09-19 Pentech Pharmaceuticals, Inc. Apomorphine-containing dosage forms for ameliorating male erectile dysfunction
US5888534A (en) * 1995-06-13 1999-03-30 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
GB9517062D0 (en) 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
GB9700878D0 (en) 1997-01-17 1997-03-05 Scherer Ltd R P Dosage forms and method for ameliorating male erectile dysfunction
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
ES2270517T3 (es) * 1997-05-19 2007-04-01 Zonagen, Inc. Terapia de combinacion para modular la respuesta sexual humana.
WO1999001108A1 (en) 1997-07-01 1999-01-14 Implico B.V. Quick release compositions
US20030091629A1 (en) 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
GB9904911D0 (en) * 1999-03-03 1999-04-28 Scherer Ltd R P Pharmaceutical compositions
GB9908014D0 (en) * 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
CA2394297A1 (en) * 1999-12-30 2001-07-12 Tap Holdings, Inc. Oral mucosal dosage forms of apomorphine
AU2001286418A1 (en) * 2000-08-08 2002-02-18 Teva Pharmaceutical Industries Ltd. Stable pergolide mesylate and process for making same
EP1363634A2 (en) * 2000-08-16 2003-11-26 PHARMACIA & UPJOHN COMPANY Compounds for the treatment of addictive disorders
SE0002934D0 (sv) 2000-08-17 2000-08-17 Axon Biochemicals Bv New aporphine esters and in their use in therapy
SE0102036D0 (sv) * 2001-06-08 2001-06-08 Axon Biochemicals Bv Pharmaceutical formulation for the efficient administration of apomorphine, 6aR- (-) -N- Propyl- norapomorphine and their derivatives and pro-drugs thereof
CN1469737A (zh) * 2000-10-16 2004-01-21 ��һ��������ҩ��ʽ���� 口腔内快速崩解的药用组合物及其制备方法
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
FR2834894B1 (fr) * 2002-01-21 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de piribedil
US7217696B2 (en) 2002-02-28 2007-05-15 A & D Bioscience, Inc. Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof
BR0308567A (pt) * 2002-03-19 2007-01-09 Michael Holick derivados de glicosìdeo e glicosìdeo de ortoéster de apomorfina, análogos, e seus usos
WO2003079980A2 (en) * 2002-03-19 2003-10-02 A & D Bioscience, Inc. Caboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof
CN100411611C (zh) * 2002-04-05 2008-08-20 欧洲凯尔蒂克公司 用于持续,不变且独立释放活性化合物的基质
WO2003086475A1 (en) * 2002-04-12 2003-10-23 A & D Bioscience, Inc. Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents, and uses thereof
AU2003241322A1 (en) * 2002-04-30 2003-11-17 Npd Llc Multi-phasic delivery via transmucosal absorption of antiemetic medicaments
US20050153928A1 (en) * 2002-05-07 2005-07-14 Holick Michael F. Conjugates comprising a central nervous system-active drug linked to glucuronic acid or glucosamine through an amide bond and uses thereof
WO2004000223A2 (en) * 2002-06-20 2003-12-31 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US20050215487A1 (en) * 2002-06-27 2005-09-29 Holick Michael F Conjugates comprising an nsaid and a sugar and uses thereof
GB0217056D0 (en) * 2002-07-23 2002-08-28 Ass Octel Use
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
GB0226076D0 (en) * 2002-11-08 2002-12-18 Rp Scherer Technologies Inc Improved formulations containing substituted imidazole derivatives
US20040156894A1 (en) * 2003-02-07 2004-08-12 Grother Leon Paul Use of edible acids in fast-dispersing pharmaceutical solid dosage forms
RU2224518C1 (ru) * 2003-02-10 2004-02-27 Дулькис Мария Дмитриевна Жидкая лекарственная форма налтрексона
MXPA05011557A (es) 2003-04-29 2006-03-09 Orexigen Therapeutics Inc Composiciones para afectar perdida de peso.
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
MXPA06007453A (es) * 2003-12-31 2007-01-31 Cima Labs Inc Forma de dosificacion de opiaceo oral efervescente.
AU2004311880B2 (en) * 2003-12-31 2010-08-05 Phoenix Labs Unlimited Company Generally linear effervescent oral fentanyl dosage form and methods of administering
US7576073B2 (en) 2004-05-28 2009-08-18 UNIVERSITé LAVAL Combined therapy for the treatment of parkinson's disease
US7972621B2 (en) * 2004-06-03 2011-07-05 R.P. Scherer Technologies, Llc Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight
KR20090033410A (ko) * 2004-06-17 2009-04-02 메르츠 파마 게엠베하 운트 코. 카가아 메만타인 또는 네라멕산의 직접 압축으로 제조된 마실수 있는 즉시 방출형 제제
EP1812081A1 (en) * 2004-11-03 2007-08-01 Clera Inc. Method to detect dopamine receptors in the functional d2high state
KR20070114734A (ko) * 2005-03-28 2007-12-04 오렉쏘 에이비 파킨슨병 치료에 유용한 새로운 약학 조성물
GB0509317D0 (en) * 2005-05-06 2005-06-15 Clarke Anthony Pharmaceutical formulation of apomorphine
US20070128285A1 (en) * 2005-07-12 2007-06-07 Chikara Jin Pharmaceutical composition for oral administration
US20070020186A1 (en) 2005-07-22 2007-01-25 Alpex Pharma S.A. Solid dosage formulations of narcotic drugs having improved buccal adsorption
EP1937270A1 (en) * 2005-09-21 2008-07-02 Brystol-Myers Squibb Company Oral administration of n-(2-chloro-6-methylphenyl)-2-[[6-4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-1,3-thiazole-5-carboxamide and salts thereof
WO2007067341A2 (en) 2005-11-22 2007-06-14 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
TW200815020A (en) * 2006-06-15 2008-04-01 Serenex Inc Stabilized tetracycline compositions
DE102006027793A1 (de) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag Opioid-Kombinations-Wafer
EP2043613A1 (en) * 2006-07-14 2009-04-08 Fmc Corporation Solid form
EP1897543A1 (en) 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine- wafer for drug substitution therapy
CA2668885C (en) 2006-11-09 2016-08-02 Orexigen Therapeutics, Inc. Methods for administering weight loss medications
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
US8741918B2 (en) 2007-06-21 2014-06-03 Veroscience Llc Parenteral formulations of dopamine agonists
US20100035886A1 (en) 2007-06-21 2010-02-11 Veroscience, Llc Parenteral formulations of dopamine agonists
WO2009003147A1 (en) * 2007-06-26 2008-12-31 Parkinson's Institute Methods and compositions for the treatment of neurological disorders
US20090004248A1 (en) * 2007-06-29 2009-01-01 Frank Bunick Dual portion dosage lozenge form
US20090004231A1 (en) 2007-06-30 2009-01-01 Popp Shane M Pharmaceutical dosage forms fabricated with nanomaterials for quality monitoring
WO2009158114A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
WO2010019856A1 (en) * 2008-08-15 2010-02-18 The Mclean Hospital Corporation Methods and kits for treatings stroke and other neurological conditions
DE102009036285A1 (de) * 2008-10-13 2010-04-15 Illinois Tool Works Inc., Glenview Verfahren zur Herstellung eines Bohrers, insbesondere eines Gesteinsbohrers
US20100116281A1 (en) 2008-11-07 2010-05-13 Jerry Wayne Marshall Tobacco products and processes
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US9044475B2 (en) 2009-06-12 2015-06-02 Cynapsus Therapeutics, Inc. Sublingual apomorphine
WO2011026080A1 (en) 2009-08-31 2011-03-03 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam, processes for preparation, and use to treat arthritis and/or pain
EP2482822B1 (en) 2009-10-01 2018-08-01 Adare Pharmaceuticals, Inc. Orally administered corticosteroid compositions
EP3254676B1 (en) * 2009-10-30 2018-11-28 IX Biopharma Ltd Fast dissolving solid dosage form
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
KR20120124423A (ko) 2010-01-11 2012-11-13 오렉시젠 세러퓨틱스 인크. 주우울증 환자들에 있어서 체중 감량 치료를 제공하는 방법
US9675102B2 (en) 2010-09-07 2017-06-13 R. J. Reynolds Tobacco Company Smokeless tobacco product comprising effervescent composition
EP3095441B1 (en) * 2010-10-08 2020-12-02 R.P. Scherer Technologies, LLC Oral vaccine fast-dissolving dosage form using starch
WO2012083269A1 (en) 2010-12-16 2012-06-21 Cynapsus Therapeutics, Inc. Sublingual films
US10881132B2 (en) 2011-12-14 2021-01-05 R.J. Reynolds Tobacco Company Smokeless tobacco product comprising effervescent composition
MA37714A1 (fr) 2012-06-06 2017-12-29 Orexigen Therapeutics Inc Méthodes de traitement de la surcharge pondérale et de l'obésité
CN105163612B (zh) 2013-03-15 2019-08-06 R·J·雷诺兹烟草公司 由材料的薄片形成加热元件、用于产生雾化器的输入端和方法,用于气雾剂递送装置的套筒以及用于组装用于吸烟物品的套筒的方法
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
CA2930410A1 (en) * 2013-11-11 2015-05-14 Impax Laboratories, Inc. Rapidly disintegrating formulations and methods of use
US8969371B1 (en) 2013-12-06 2015-03-03 Orexigen Therapeutics, Inc. Compositions and methods for weight loss in at risk patient populations
JP7211706B2 (ja) 2015-04-21 2023-01-24 サノヴィオン ファーマシュティカルズ インコーポレーテッド 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法
US10611505B2 (en) 2015-05-04 2020-04-07 Rai Strategic Holdings, Inc. Dispensing machine for aerosol precursor
US10238145B2 (en) 2015-05-19 2019-03-26 Rai Strategic Holdings, Inc. Assembly substation for assembling a cartridge for a smoking article
US20170112194A1 (en) 2015-10-21 2017-04-27 Rai Strategic Holdings, Inc. Rechargeable lithium-ion capacitor for an aerosol delivery device
US10820630B2 (en) 2015-11-06 2020-11-03 Rai Strategic Holdings, Inc. Aerosol delivery device including a wirelessly-heated atomizer and related method
US10104912B2 (en) 2016-01-20 2018-10-23 Rai Strategic Holdings, Inc. Control for an induction-based aerosol delivery device
US11207478B2 (en) 2016-03-25 2021-12-28 Rai Strategic Holdings, Inc. Aerosol production assembly including surface with micro-pattern
US10334880B2 (en) 2016-03-25 2019-07-02 Rai Strategic Holdings, Inc. Aerosol delivery device including connector comprising extension and receptacle
US10405579B2 (en) 2016-04-29 2019-09-10 Rai Strategic Holdings, Inc. Methods for assembling a cartridge for an aerosol delivery device, and associated systems and apparatuses
US11019847B2 (en) 2016-07-28 2021-06-01 Rai Strategic Holdings, Inc. Aerosol delivery devices including a selector and related methods
TWI728172B (zh) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
US10477896B2 (en) 2016-10-12 2019-11-19 Rai Strategic Holdings, Inc. Photodetector for measuring aerosol precursor composition in an aerosol delivery device
US20180132529A1 (en) 2016-11-14 2018-05-17 Rai Strategic Holdings, Inc. Aerosol delivery device with integrated wireless connectivity for temperature monitoring
US20180132528A1 (en) 2016-11-14 2018-05-17 Rai Strategic Holdings, Inc. Photoelectric proximity sensor for gesture-based control of an aerosol delivery device
US10524508B2 (en) 2016-11-15 2020-01-07 Rai Strategic Holdings, Inc. Induction-based aerosol delivery device
US10537137B2 (en) 2016-11-22 2020-01-21 Rai Strategic Holdings, Inc. Rechargeable lithium-ion battery for an aerosol delivery device
CN110022706B (zh) 2016-12-01 2022-10-04 莱战略控股公司 用于气溶胶递送设备的可再充电的锂离子电容器
EP3549235B1 (en) 2016-12-02 2021-05-05 RAI Strategic Holdings, Inc. Induction charging for an aerosol delivery device
US11013266B2 (en) 2016-12-09 2021-05-25 Rai Strategic Holdings, Inc. Aerosol delivery device sensory system including an infrared sensor and related method
US10517326B2 (en) 2017-01-27 2019-12-31 Rai Strategic Holdings, Inc. Secondary battery for an aerosol delivery device
US10759554B2 (en) 2017-02-02 2020-09-01 Rai Strategic Holdings, Inc. Dispenser unit for aerosol precursor
US10827783B2 (en) 2017-02-27 2020-11-10 Rai Strategic Holdings, Inc. Digital compass for an aerosol delivery device
US10314340B2 (en) 2017-04-21 2019-06-11 Rai Strategic Holdings, Inc. Refillable aerosol delivery device and related method
US11297876B2 (en) 2017-05-17 2022-04-12 Rai Strategic Holdings, Inc. Aerosol delivery device
US10517330B2 (en) 2017-05-23 2019-12-31 RAI Stategic Holdings, Inc. Heart rate monitor for an aerosol delivery device
US10349674B2 (en) 2017-07-17 2019-07-16 Rai Strategic Holdings, Inc. No-heat, no-burn smoking article
US11337456B2 (en) 2017-07-17 2022-05-24 Rai Strategic Holdings, Inc. Video analytics camera system for an aerosol delivery device
US10791761B2 (en) 2017-08-17 2020-10-06 Rai Strategic Holdings, Inc. Microtextured liquid transport element for aerosol delivery device
US10505383B2 (en) 2017-09-19 2019-12-10 Rai Strategic Holdings, Inc. Intelligent charger for an aerosol delivery device
US11039645B2 (en) 2017-09-19 2021-06-22 Rai Strategic Holdings, Inc. Differential pressure sensor for an aerosol delivery device
US10660370B2 (en) 2017-10-12 2020-05-26 Rai Strategic Holdings, Inc. Aerosol delivery device including a control body, an atomizer body, and a cartridge and related methods
US12114688B2 (en) 2017-10-24 2024-10-15 Rai Strategic Holdings, Inc. Method for formulating aerosol precursor for aerosol delivery device
US10806181B2 (en) 2017-12-08 2020-10-20 Rai Strategic Holdings, Inc. Quasi-resonant flyback converter for an induction-based aerosol delivery device
US10555558B2 (en) 2017-12-29 2020-02-11 Rai Strategic Holdings, Inc. Aerosol delivery device providing flavor control
US10813385B2 (en) 2018-03-09 2020-10-27 Rai Strategic Holdings, Inc. Buck regulator with operational amplifier feedback for an aerosol delivery device
US11206864B2 (en) 2018-03-26 2021-12-28 Rai Strategic Holdings, Inc. Aerosol delivery device providing flavor control
US10959459B2 (en) 2018-05-16 2021-03-30 Rai Strategic Holdings, Inc. Voltage regulator for an aerosol delivery device
US11094993B2 (en) 2018-08-10 2021-08-17 Rai Strategic Holdings, Inc. Charge circuitry for an aerosol delivery device
US10939707B2 (en) 2018-08-23 2021-03-09 Rai Strategic Holdings, Inc. Aerosol delivery device with segmented electrical heater
US11592793B2 (en) 2018-11-19 2023-02-28 Rai Strategic Holdings, Inc. Power control for an aerosol delivery device
US11614720B2 (en) 2018-11-19 2023-03-28 Rai Strategic Holdings, Inc. Temperature control in an aerosol delivery device
US11753750B2 (en) 2018-11-20 2023-09-12 R.J. Reynolds Tobacco Company Conductive aerosol generating composite substrate for aerosol source member
US11547816B2 (en) 2018-11-28 2023-01-10 Rai Strategic Holdings, Inc. Micropump for an aerosol delivery device
US11096419B2 (en) 2019-01-29 2021-08-24 Rai Strategic Holdings, Inc. Air pressure sensor for an aerosol delivery device
US20200245696A1 (en) 2019-02-06 2020-08-06 Rai Strategic Holdings, Inc. Buck-boost regulator circuit for an aerosol delivery device
US11456480B2 (en) 2019-02-07 2022-09-27 Rai Strategic Holdings, Inc. Non-inverting amplifier circuit for an aerosol delivery device
US12140978B2 (en) 2019-03-01 2024-11-12 Rai Strategic Holdings, Inc. Temperature control circuitry for an aerosol delivery device
US11324249B2 (en) 2019-03-06 2022-05-10 R.J. Reynolds Tobacco Company Aerosol delivery device with nanocellulose substrate
CN118177412A (zh) 2019-03-08 2024-06-14 莱战略控股公司 用于气溶胶递送装置的乳酸水解方法
US11935350B2 (en) 2019-04-02 2024-03-19 Rai Strategic Holdings, Inc. Functional control and age verification of electronic devices through speaker communication
US11676438B2 (en) 2019-04-02 2023-06-13 Rai Strategic Holdings, Inc. Authentication and age verification for an aerosol delivery device
US11200770B2 (en) 2019-04-02 2021-12-14 Rai Strategic Holdings, Inc. Functional control and age verification of electronic devices through visual communication
US11783395B2 (en) 2019-04-24 2023-10-10 Rai Strategic Holdings, Inc. Decentralized identity storage for tobacco products
US11690405B2 (en) 2019-04-25 2023-07-04 Rai Strategic Holdings, Inc. Artificial intelligence in an aerosol delivery device
US12232543B2 (en) 2019-05-17 2025-02-25 Rai Strategic Holdings, Inc. Age verification with registered cartridges for an aerosol delivery device
US12022859B2 (en) 2019-07-18 2024-07-02 R.J. Reynolds Tobacco Company Thermal energy absorbers for tobacco heating products
WO2021038493A1 (en) 2019-08-29 2021-03-04 Rai Strategic Holdings, Inc. Dual-chamber aerosol dispenser
GB201912686D0 (en) 2019-09-04 2019-10-16 Reown Pharma Inc Pharmaceutical composition
US11785991B2 (en) 2019-10-04 2023-10-17 Rai Strategic Holdings, Inc. Use of infrared temperature detection in an aerosol delivery device
US11470689B2 (en) 2019-10-25 2022-10-11 Rai Strategic Holdings, Inc. Soft switching in an aerosol delivery device
US12446629B2 (en) 2019-11-18 2025-10-21 Rai Strategic Holdings, Inc. Security tag
KR20220133203A (ko) 2019-12-30 2022-10-04 레이 스트라티직 홀딩스, 인크. 에어로졸 전달 장치용 심박수 모니터
AR121656A1 (es) 2020-03-26 2022-06-29 Rai Strategic Holdings Inc Métodos, aparatos y sistemas para activar un dispositivo antes de accionar el dispositivo
US12484610B2 (en) 2020-04-16 2025-12-02 R.J. Reynolds Tobacco Company Aerosol delivery device including a segregated substrate
US20210321674A1 (en) 2020-04-21 2021-10-21 Rai Strategic Holdings, Inc. Pressure-sensing user interface for an aerosol delivery device
US11839240B2 (en) 2020-04-29 2023-12-12 Rai Strategic Holdings, Inc. Piezo sensor for a power source
WO2021250516A1 (en) 2020-06-08 2021-12-16 Nicoventures Trading Limited Effervescent oral composition comprising an active ingredient
US11771132B2 (en) 2020-08-27 2023-10-03 Rai Strategic Holdings, Inc. Atomization nozzle for aerosol delivery device
US11771136B2 (en) 2020-09-28 2023-10-03 Rai Strategic Holdings, Inc. Aerosol delivery device
CA3198547A1 (en) 2020-11-16 2022-05-19 Mark RIDALL Rapidly infusing platform and compositions for therapeutic treatment in humans
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
US20220183389A1 (en) 2020-12-11 2022-06-16 Rai Strategic Holdings, Inc. Sleeve for smoking article
MX2023012535A (es) 2021-04-22 2024-01-24 Nicoventures Trading Ltd Composicion oral efervescente.
TW202448511A (zh) 2023-05-11 2024-12-16 英商康泰倫特英國斯文敦載迪斯有限公司 增加活性醫藥成分之胃前吸收的滲透性
WO2025064381A1 (en) * 2023-09-18 2025-03-27 Phathom Pharmaceuticals Inc. Method for preparing vonoprazan with reduced nitrosamine
EP4585059A1 (en) 2024-01-12 2025-07-16 Nicoventures Trading Limited Effervescent pouched product

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
DE3216869A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Synergistische kombination mit zytostatischer wirkung
IT1200609B (it) * 1985-04-04 1989-01-27 Poli Ind Chimica Spa Composizione farmaceutice per il trattamento delle turbe cerebrovascolari e del cervello anziano
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US5785989A (en) 1985-05-01 1998-07-28 University Utah Research Foundation Compositions and methods of manufacturing of oral dissolvable medicaments
HU193780B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 2-halogeno-6-methyl-ergol-9-ene derivatives and acid additional salts thereof
JPS63501717A (ja) * 1985-10-29 1988-07-14 ベーカー・カミンス・デルマトロジカルス・インコーポレーテッド 抗原誘発性アレルギ−反応を阻止するための方法および組成物
NZ220599A (en) * 1986-06-16 1990-10-26 Merck & Co Inc Controlled release oral dosage formulation of carbidopa and levodopa
DE3631088A1 (de) * 1986-09-12 1988-06-23 Ferring Arzneimittel Gmbh Verwendung von opiat-antagonisten zur diagnose und therapie von hypothalamischen funktionsstoerungen
US4855326A (en) * 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
GB8712073D0 (en) * 1987-05-21 1987-06-24 Smith Kline French Lab Medicament
US5234957A (en) * 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
DE3831088A1 (de) * 1988-09-13 1990-03-15 Jochen Gasda Preisauszeichnungseinrichtung und verfahren zum aufbringen von preisauszeichnungen auf einen preisauszeichnungstraeger
US5073374A (en) * 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
AU646232B2 (en) 1989-10-02 1994-02-17 Cima Labs, Inc. Effervescent dosage form and method of administering same
GB9015095D0 (en) * 1990-07-09 1990-08-29 Smith Kline French Lab Therapeutic method
GB9216297D0 (en) * 1991-08-15 1992-09-16 Ici Plc Therapeutic agents
JP3706129B2 (ja) * 1991-11-04 2005-10-12 フイズ テクノロジーズ リミテッド 疎水性液体用の水溶性送出系
ATE172637T1 (de) * 1991-12-24 1998-11-15 Yamanouchi Pharma Co Ltd Intrabukkal desintegrierende zubereitung und ihre herstellung
EP0553777B1 (en) * 1992-01-29 2002-04-24 Takeda Chemical Industries, Ltd. Fast dissolving tablet and its production
HUT75616A (en) * 1992-03-17 1997-05-28 Pfizer Method for prooucing porous delivery devices
US5298261A (en) 1992-04-20 1994-03-29 Oregon Freeze Dry, Inc. Rapidly distintegrating tablet
IL105553A (en) * 1992-05-06 1998-01-04 Janssen Pharmaceutica Inc Solid dosage form comprising a porous network of matrix forming material which disperses rapidly in water
CA2095776C (en) * 1992-05-12 2007-07-10 Richard C. Fuisz Rapidly dispersable compositions containing polydextrose
IL108366A (en) * 1993-03-11 1999-11-30 Taro Vit Ind Ltd Semi-solid pharmaceutical compounds and a device for their use
DK0865789T3 (da) * 1993-03-26 2005-07-18 Franciscus Wilhelmus He Merkus Farmaceutiske præparater til intranasal administration af dihydroergotamin
DE4320678C2 (de) 1993-06-22 1996-04-11 Branko Dipl Ing Klasnic Vorrichtung zum Entfernen von Rechengut aus einer mit einer verunreinigten Flüssigkeit durchströmten Zulaufrinne, insbesondere von Kläranlagen
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
GB9517062D0 (en) 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions

Also Published As

Publication number Publication date
HU222197B1 (hu) 2003-05-28
AU6750996A (en) 1997-03-12
NO980669L (no) 1998-04-17
EE9800050A (et) 1998-08-17
CA2229597C (en) 2004-02-10
DK0850050T3 (da) 2000-10-16
PL324988A1 (en) 1998-07-06
HUP9900183A2 (hu) 1999-05-28
EE03471B1 (et) 2001-08-15
JPH11511162A (ja) 1999-09-28
AU709641B2 (en) 1999-09-02
EP0850050B1 (en) 2000-09-13
DE69610323T2 (de) 2001-02-22
WO1997006786A1 (en) 1997-02-27
SK19198A3 (en) 1998-09-09
US6316027B1 (en) 2001-11-13
UA64700C2 (en) 2004-03-15
MX9801305A (es) 1998-05-31
CZ293129B6 (cs) 2004-02-18
ZA967032B (en) 1997-03-04
BG63188B1 (bg) 2001-06-29
CZ45598A3 (cs) 1998-07-15
GR3034583T3 (en) 2001-01-31
ES2151672T3 (es) 2001-01-01
NO313368B1 (no) 2002-09-23
BG102254A (en) 1998-10-30
ATE196249T1 (de) 2000-09-15
CA2229597A1 (en) 1997-02-27
NO980669D0 (no) 1998-02-17
NZ315740A (en) 1999-06-29
DE69610323D1 (de) 2000-10-19
HUP9900183A3 (en) 1999-11-29
PL187718B1 (pl) 2004-09-30
PT850050E (pt) 2001-01-31
RU2189226C2 (ru) 2002-09-20
RO119066B1 (ro) 2004-03-30
BR9610424A (pt) 1999-03-30
EP0850050A1 (en) 1998-07-01
GB9517062D0 (en) 1995-10-25

Similar Documents

Publication Publication Date Title
SK283597B6 (sk) Farmaceutický prípravok na orálne podanie, spôsob jeho prípravy a jeho použitie, farmaceutický produkt a súprava
US20020156056A1 (en) Oral fast-dissolving compositions for dopamine agonists
US7090866B2 (en) Opioid agonist in a fast dispersing dosage form
JP3273141B2 (ja) モノアミンオキシダーゼbインヒビターからなる医薬組成物
JP2007523091A (ja) 口腔粘膜を介して催眠剤をデリバリーするための組成物及びその使用方法
JP5474033B2 (ja) 置換イミダゾール誘導体を含む改良された製剤
NZ548856A (en) Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof
US20060141032A1 (en) Effervescent formulations comprising apomorphine
CZ247299A3 (cs) Použití farmaceutické směsi pro ústní podání
MXPA99006585A (en) Dosage forms and method for ameliorating male erectile dysfunction

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20130816