SK283137B6 - Farmaceutické kompozície na liečbu poruchy agregácie krvných doštičiek a spôsob jej prípravy - Google Patents

Farmaceutické kompozície na liečbu poruchy agregácie krvných doštičiek a spôsob jej prípravy Download PDF

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Publication number
SK283137B6
SK283137B6 SK764-99A SK76499A SK283137B6 SK 283137 B6 SK283137 B6 SK 283137B6 SK 76499 A SK76499 A SK 76499A SK 283137 B6 SK283137 B6 SK 283137B6
Authority
SK
Slovakia
Prior art keywords
pharmaceutical composition
composition according
mannitol
halogen
drying
Prior art date
Application number
SK764-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK76499A3 (en
Inventor
Chris Bland
Gerald Steele
Original Assignee
Astra Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceuticals Ltd. filed Critical Astra Pharmaceuticals Ltd.
Publication of SK76499A3 publication Critical patent/SK76499A3/sk
Publication of SK283137B6 publication Critical patent/SK283137B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK764-99A 1996-12-20 1997-12-11 Farmaceutické kompozície na liečbu poruchy agregácie krvných doštičiek a spôsob jej prípravy SK283137B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9604795A SE9604795D0 (sv) 1996-12-20 1996-12-20 New pharmaceutical formulation
PCT/SE1997/002068 WO1998028009A1 (en) 1996-12-20 1997-12-11 Pharmaceutical compositions for freeze drying

Publications (2)

Publication Number Publication Date
SK76499A3 SK76499A3 (en) 1999-11-08
SK283137B6 true SK283137B6 (sk) 2003-03-04

Family

ID=20405148

Family Applications (1)

Application Number Title Priority Date Filing Date
SK764-99A SK283137B6 (sk) 1996-12-20 1997-12-11 Farmaceutické kompozície na liečbu poruchy agregácie krvných doštičiek a spôsob jej prípravy

Country Status (36)

Country Link
US (1) US6114313A (xx)
EP (1) EP1007094B1 (xx)
JP (1) JP4488538B2 (xx)
KR (1) KR100552880B1 (xx)
CN (1) CN1121875C (xx)
AR (1) AR010377A1 (xx)
AT (1) ATE221787T1 (xx)
AU (1) AU758857B2 (xx)
BR (1) BR9713974B1 (xx)
CA (1) CA2275153C (xx)
CZ (1) CZ300635B6 (xx)
DE (1) DE69714616T2 (xx)
DK (1) DK1007094T3 (xx)
EE (1) EE03857B1 (xx)
ES (1) ES2182133T3 (xx)
FR (1) FR15C0060I2 (xx)
HK (1) HK1026366A1 (xx)
HU (1) HU226616B1 (xx)
ID (1) ID21635A (xx)
IL (1) IL130449A0 (xx)
IS (1) IS1897B (xx)
MY (1) MY121982A (xx)
NO (1) NO327142B1 (xx)
NZ (1) NZ336027A (xx)
PL (1) PL190493B1 (xx)
PT (1) PT1007094E (xx)
RU (1) RU2205012C2 (xx)
SA (1) SA97180719B1 (xx)
SE (1) SE9604795D0 (xx)
SI (1) SI1007094T1 (xx)
SK (1) SK283137B6 (xx)
TR (1) TR199901412T2 (xx)
TW (1) TW522015B (xx)
UA (1) UA66779C2 (xx)
WO (1) WO1998028009A1 (xx)
ZA (1) ZA9711055B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702680D0 (sv) * 1997-07-11 1997-07-11 Astra Pharma Prod New formulation
US20130303477A1 (en) 2008-05-13 2013-11-14 The Medicines Company Maintenance of Platelet Inhibition During Antiplatelet Therapy
US9427448B2 (en) 2009-11-11 2016-08-30 The Medicines Company Methods of treating, reducing the incidence of, and/or preventing ischemic events
US20120141468A1 (en) 2008-05-13 2012-06-07 Lisa Ruderman Chen Maintenance of platelet inhibition during antiplatelet therapy
US8759316B2 (en) 2008-05-13 2014-06-24 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
WO2009140092A1 (en) 2008-05-13 2009-11-19 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
US10376532B2 (en) 2009-11-11 2019-08-13 Chiesi Farmaceutici, S.P.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
AU2010319612B2 (en) 2009-11-11 2016-01-14 Chiesi Farmaceutici S.P.A. Methods of treating or preventing stent thrombosis
BR112013020377B1 (pt) 2011-02-09 2022-06-07 Chiesi Farmaceutici S.P.A. Usos de um antagonista do receptor p2y12 reversível na fabricação de um medicamento útil para o tratamento da hipertensão pulmonar
EP2964233B1 (en) 2013-03-09 2021-12-15 Chiesi Farmaceutici S.p.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
CN103772461A (zh) * 2014-01-06 2014-05-07 南京正科制药有限公司 一种坎格雷洛晶型ⅰ
WO2016114818A1 (en) * 2015-01-14 2016-07-21 The Medicines Company Pharmaceutical formulations comprising high purity cangrelor and methods for preparing and using the same
EP3641784A1 (en) 2017-06-23 2020-04-29 Chiesi Farmaceutici S.p.A. Method of preventing of systemic-to-pulmonary-artery shunt thrombosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5637967B2 (xx) * 1973-05-17 1981-09-03
JPH01228915A (ja) * 1988-03-09 1989-09-12 Dai Ichi Seiyaku Co Ltd Ａｔｐ凍結乾燥製剤
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
CZ281415B6 (cs) * 1989-11-09 1996-09-11 Masarykova Nemocnice S Poliklinikou Iii. Typu Způsob přípravy přenosového faktoru z buffy coatu savčí krve
GB9010742D0 (en) * 1990-05-14 1990-07-04 Quadrant Bioresources Ltd Stabilization of biological macromolecular substances
AU659645B2 (en) * 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
ES2129048T3 (es) * 1991-12-09 1999-06-01 Asahi Chemical Ind Composicion estabilizada de hormona paratiroide.

Also Published As

Publication number Publication date
FR15C0060I2 (fr) 2016-04-22
WO1998028009A1 (en) 1998-07-02
ZA9711055B (en) 1998-07-08
MY121982A (en) 2006-03-31
CN1240362A (zh) 2000-01-05
HK1026366A1 (en) 2000-12-15
JP4488538B2 (ja) 2010-06-23
FR15C0060I1 (xx) 2015-10-23
IS5064A (is) 1999-06-03
RU2205012C2 (ru) 2003-05-27
HUP0000572A3 (en) 2002-10-28
TR199901412T2 (xx) 1999-08-23
AU758857B2 (en) 2003-04-03
PL190493B1 (pl) 2005-12-30
BR9713974A (pt) 2000-04-11
IL130449A0 (en) 2000-06-01
ATE221787T1 (de) 2002-08-15
CN1121875C (zh) 2003-09-24
EE03857B1 (et) 2002-10-15
SE9604795D0 (sv) 1996-12-20
HU226616B1 (en) 2009-04-28
NZ336027A (en) 2001-03-30
ID21635A (id) 1999-07-08
DE69714616D1 (de) 2002-09-12
UA66779C2 (uk) 2004-06-15
EP1007094A1 (en) 2000-06-14
ES2182133T3 (es) 2003-03-01
DE69714616T2 (de) 2003-04-03
AR010377A1 (es) 2000-06-07
DK1007094T3 (da) 2002-10-28
HUP0000572A2 (hu) 2001-05-28
AU5351598A (en) 1998-07-17
BR9713974B1 (pt) 2010-02-23
KR20000069598A (ko) 2000-11-25
CZ300635B6 (cs) 2009-07-08
CA2275153C (en) 2008-03-25
NO327142B1 (no) 2009-05-04
JP2001507022A (ja) 2001-05-29
PL334006A1 (en) 2000-01-31
SA97180719B1 (ar) 2006-05-13
EE9900260A (et) 2000-02-15
NO993067D0 (no) 1999-06-21
NO993067L (no) 1999-08-09
CA2275153A1 (en) 1998-07-02
TW522015B (en) 2003-03-01
SI1007094T1 (en) 2003-02-28
EP1007094B1 (en) 2002-08-07
IS1897B (is) 2003-10-20
CZ220199A3 (cs) 1999-11-17
US6114313A (en) 2000-09-05
KR100552880B1 (ko) 2006-02-20
SK76499A3 (en) 1999-11-08
PT1007094E (pt) 2002-12-31

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MK4A Patent expired

Expiry date: 20171211