SK281222B6 - Arylidén-1-azacykloalkány a aryalkyl-1-azacykloalkány, ich soli, spôsob výroby, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Arylidén-1-azacykloalkány a aryalkyl-1-azacykloalkány, ich soli, spôsob výroby, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

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Publication number
SK281222B6
SK281222B6 SK1073-93A SK107393A SK281222B6 SK 281222 B6 SK281222 B6 SK 281222B6 SK 107393 A SK107393 A SK 107393A SK 281222 B6 SK281222 B6 SK 281222B6
Authority
SK
Slovakia
Prior art keywords
group
piperidine
oxazolin
formula
benzylidene
Prior art date
Application number
SK1073-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK107393A3 (en
Inventor
Roland Maier
Peter MLLER
Eberhard Woitun
Rudolf Hurnaus
Michael Mark
Bernhard Eisele
Ralph-Michael Budzinski
Gerhard Hallermayer
Original Assignee
Karl Thomae Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4235590A external-priority patent/DE4235590A1/de
Application filed by Karl Thomae Gmbh filed Critical Karl Thomae Gmbh
Publication of SK107393A3 publication Critical patent/SK107393A3/sk
Publication of SK281222B6 publication Critical patent/SK281222B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Catalysts (AREA)
  • Ink Jet (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK1073-93A 1992-10-22 1993-10-05 Arylidén-1-azacykloalkány a aryalkyl-1-azacykloalkány, ich soli, spôsob výroby, farmaceutický prostriedok s ich obsahom a ich použitie SK281222B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4235590A DE4235590A1 (de) 1992-10-22 1992-10-22 Aryliden-l-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4303840A DE4303840A1 (de) 1992-10-22 1993-02-10 Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
SK107393A3 SK107393A3 (en) 1994-09-07
SK281222B6 true SK281222B6 (sk) 2001-01-18

Family

ID=25919689

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1073-93A SK281222B6 (sk) 1992-10-22 1993-10-05 Arylidén-1-azacykloalkány a aryalkyl-1-azacykloalkány, ich soli, spôsob výroby, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (21)

Country Link
EP (1) EP0596326B1 (zh)
JP (1) JP3396517B2 (zh)
KR (1) KR100306520B1 (zh)
CN (1) CN1040873C (zh)
AT (1) ATE126797T1 (zh)
AU (1) AU665648B2 (zh)
CA (1) CA2108817C (zh)
CZ (1) CZ286025B6 (zh)
DE (2) DE4303840A1 (zh)
DK (1) DK0596326T3 (zh)
ES (1) ES2078787T3 (zh)
FI (1) FI934665A (zh)
GR (1) GR3017692T3 (zh)
HK (1) HK1000285A1 (zh)
HU (1) HU221630B1 (zh)
IL (1) IL107342A (zh)
NO (1) NO300843B1 (zh)
NZ (1) NZ250018A (zh)
PL (1) PL173775B1 (zh)
RU (1) RU2126400C1 (zh)
SK (1) SK281222B6 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4234295A1 (de) * 1992-10-12 1994-04-14 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
IL110943A (en) * 1994-09-13 1997-02-18 Univ Ramot Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders
DE19754795A1 (de) * 1997-12-10 1999-06-17 Boehringer Ingelheim Pharma Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
US6228868B1 (en) 1998-07-27 2001-05-08 Abbott Laboratories Oxazoline antiproliferative agents
WO2000006556A1 (en) * 1998-07-27 2000-02-10 Abbott Laboratories Substituted oxazolines as antiproliferative agents
AU2003223510B2 (en) 2002-04-12 2008-05-08 Merck Sharp & Dohme Corp. Bicyclic amides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863932A (en) * 1988-03-11 1989-09-05 Somatogenetics International, Inc. Squalene oxide cyclase inhibitors and therapeutic use thereof
CA2025490C (en) * 1989-09-22 2003-09-16 James R. Mccarthy Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis
CA2047375C (en) * 1990-07-25 2003-04-15 Charlotte L. Barney Piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
US5084461A (en) * 1991-03-27 1992-01-28 Merrell Dow Pharmaceuticals Inc. Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
ATE126797T1 (de) 1995-09-15
CA2108817A1 (en) 1994-04-23
PL300834A1 (en) 1994-05-16
IL107342A (en) 1997-07-13
HU9302986D0 (en) 1994-01-28
FI934665A (fi) 1994-04-23
HU221630B1 (hu) 2002-12-28
CZ286025B6 (cs) 1999-12-15
GR3017692T3 (en) 1996-01-31
IL107342A0 (en) 1994-01-25
AU4913593A (en) 1994-05-05
HUT68958A (en) 1995-08-28
KR100306520B1 (ko) 2001-11-30
JPH06192256A (ja) 1994-07-12
ES2078787T3 (es) 1995-12-16
AU665648B2 (en) 1996-01-11
CN1090849A (zh) 1994-08-17
CZ223693A3 (en) 1994-05-18
DE59300507D1 (de) 1995-09-28
DK0596326T3 (da) 1996-01-15
HK1000285A1 (en) 1998-02-20
NO933790D0 (no) 1993-10-21
EP0596326B1 (de) 1995-08-23
EP0596326A1 (de) 1994-05-11
CN1040873C (zh) 1998-11-25
FI934665A0 (fi) 1993-10-22
NO300843B1 (no) 1997-08-04
CA2108817C (en) 2004-12-07
DE4303840A1 (de) 1994-08-11
PL173775B1 (pl) 1998-04-30
KR940009181A (ko) 1994-05-20
NZ250018A (en) 1995-07-26
RU2126400C1 (ru) 1999-02-20
SK107393A3 (en) 1994-09-07
JP3396517B2 (ja) 2003-04-14
NO933790L (no) 1994-04-25

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