SK281089B6 - Dna sekvencie a proteíny vzťahujúce sa na lipázu stimulovanú žlčovou soľou, spôsob výroby proteínov, farmaceutické kompozície s ich obsahom a ich použitie - Google Patents

Dna sekvencie a proteíny vzťahujúce sa na lipázu stimulovanú žlčovou soľou, spôsob výroby proteínov, farmaceutické kompozície s ich obsahom a ich použitie Download PDF

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Publication number
SK281089B6
SK281089B6 SK1644-91A SK164491A SK281089B6 SK 281089 B6 SK281089 B6 SK 281089B6 SK 164491 A SK164491 A SK 164491A SK 281089 B6 SK281089 B6 SK 281089B6
Authority
SK
Slovakia
Prior art keywords
protein
amino acid
vii
bssl
human milk
Prior art date
Application number
SK1644-91A
Other languages
English (en)
Slovak (sk)
Other versions
SK164491A3 (en
Inventor
Gunnar Bjursell
Lars Bl�Ckberg
Peter Carlsson
Sven Enerb�Ck
Olle Hernell
Jeanette Nilsson
Thomas Olivecrona
Original Assignee
Aktiebolaget Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Astra filed Critical Aktiebolaget Astra
Publication of SK164491A3 publication Critical patent/SK164491A3/sk
Publication of SK281089B6 publication Critical patent/SK281089B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK1644-91A 1990-06-01 1991-05-31 Dna sekvencie a proteíny vzťahujúce sa na lipázu stimulovanú žlčovou soľou, spôsob výroby proteínov, farmaceutické kompozície s ich obsahom a ich použitie SK281089B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9001985A SE9001985D0 (sv) 1990-06-01 1990-06-01 New chemical products

Publications (2)

Publication Number Publication Date
SK164491A3 SK164491A3 (en) 1995-07-11
SK281089B6 true SK281089B6 (sk) 2000-11-07

Family

ID=20379662

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1644-91A SK281089B6 (sk) 1990-06-01 1991-05-31 Dna sekvencie a proteíny vzťahujúce sa na lipázu stimulovanú žlčovou soľou, spôsob výroby proteínov, farmaceutické kompozície s ich obsahom a ich použitie

Country Status (44)

Country Link
EP (1) EP0535048B1 (sh)
JP (1) JPH05507201A (sh)
KR (1) KR100212411B1 (sh)
CN (2) CN1075113C (sh)
AP (1) AP207A (sh)
AT (1) ATE151077T1 (sh)
AU (1) AU651979B2 (sh)
BG (1) BG61165B1 (sh)
CA (1) CA2083396C (sh)
CZ (1) CZ287470B6 (sh)
DE (1) DE69125489T2 (sh)
DK (1) DK0535048T3 (sh)
DZ (1) DZ1503A1 (sh)
EG (1) EG19937A (sh)
ES (1) ES2099159T3 (sh)
FI (1) FI114639B (sh)
GR (1) GR3023618T3 (sh)
HK (1) HK62497A (sh)
HR (1) HRP920771B1 (sh)
HU (1) HU215258B (sh)
IE (1) IE911844A1 (sh)
IL (1) IL98273A (sh)
IS (1) IS1751B (sh)
JO (1) JO1694B1 (sh)
LT (1) LT4020B (sh)
LV (1) LV10292B (sh)
MA (1) MA22166A1 (sh)
MY (1) MY111245A (sh)
NO (1) NO322962B1 (sh)
NZ (1) NZ238223A (sh)
PH (1) PH30761A (sh)
PL (1) PL166534B1 (sh)
PT (1) PT97836B (sh)
RO (1) RO114793B1 (sh)
RU (1) RU2140983C1 (sh)
SE (1) SE9001985D0 (sh)
SG (1) SG48078A1 (sh)
SK (1) SK281089B6 (sh)
TN (1) TNSN91041A1 (sh)
TW (1) TW221712B (sh)
UA (1) UA39165C2 (sh)
WO (1) WO1991018923A1 (sh)
YU (1) YU49138B (sh)
ZA (1) ZA913778B (sh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP930935A2 (en) * 1992-06-11 1994-12-31 Astra Ab New dna sequences
IS4130A (is) * 1993-03-01 1994-09-02 Ab Astra Ný fjölpeptíð
SE9300686D0 (sv) 1993-03-01 1993-03-01 Astra Ab Novel polypeptides
FR2754827B1 (fr) * 1996-10-17 1998-12-24 Biocem Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations
JP2000026311A (ja) * 1998-07-02 2000-01-25 Amano Pharmaceut Co Ltd 胃排出能亢進剤組成物
US20090226904A1 (en) * 2005-12-01 2009-09-10 University Of Bergen Diagnosis and treatment of exocrine pancreatic dysfunction and diabetes
SI3205351T1 (sl) * 2010-04-23 2023-09-29 Alexion Pharmaceuticals, Inc., Encim za bolezen lizosomskega shranjevanja
SG188456A1 (en) 2010-09-09 2013-04-30 Synageva Biopharma Corp Use of lysosomal acid lipase for treating lysosomal acid lipase deficiency in patients
CA2812852A1 (en) 2010-10-21 2012-04-26 Swedish Orphan Biovitrum Ab (Publ) Method to increase the absorption of unsaturated fatty acids by human infants
CN103200957A (zh) 2010-10-21 2013-07-10 瑞典孤儿比奥维特鲁姆有限公司 提高人婴儿之生长速度的方法
UY37680A (es) 2017-06-19 2019-01-31 Swedish Orphan Biovitrum Ab Publ Proteína de fusión con polipéptido de extensión de vida media
AU2020336468A1 (en) 2019-08-30 2022-03-03 Societe Des Produits Nestle S.A. Engineered lipase variants

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131418A1 (en) * 1983-07-01 1985-01-16 Celltech Limited Proteins, pharmaceutical compositons, genes, vectors, host organisms and processes for their production

Also Published As

Publication number Publication date
FI114639B (fi) 2004-11-30
TNSN91041A1 (fr) 1992-10-25
PT97836A (pt) 1992-02-28
RO114793B1 (ro) 1999-07-30
HU215258B (hu) 1998-11-30
IE911844A1 (en) 1991-12-04
EP0535048B1 (en) 1997-04-02
UA39165C2 (uk) 2001-06-15
NZ238223A (en) 1993-05-26
YU49138B (sh) 2004-03-12
EP0535048A1 (en) 1993-04-07
AU7964591A (en) 1991-12-31
DE69125489D1 (de) 1997-05-07
CN1326782A (zh) 2001-12-19
NO322962B1 (no) 2006-12-18
IS3710A7 (is) 1991-12-02
MY111245A (en) 1999-10-30
NO924528L (no) 1992-11-24
FI925453A (fi) 1992-11-30
LT4020B (en) 1996-08-26
FI925453A0 (fi) 1992-11-30
HUT63184A (en) 1993-07-28
PL166534B1 (pl) 1995-05-31
IS1751B (is) 2000-07-21
DZ1503A1 (fr) 2004-09-13
ZA913778B (en) 1992-02-26
RU2140983C1 (ru) 1999-11-10
CN1064313A (zh) 1992-09-09
NO924528D0 (no) 1992-11-24
CN1075113C (zh) 2001-11-21
HK62497A (en) 1997-05-16
GR3023618T3 (en) 1997-08-29
CA2083396C (en) 2006-09-19
CA2083396A1 (en) 1991-12-02
CZ287470B6 (cs) 2000-12-13
ATE151077T1 (de) 1997-04-15
IL98273A (en) 2005-11-20
JPH05507201A (ja) 1993-10-21
ES2099159T3 (es) 1997-05-16
LV10292A (lv) 1994-10-20
JO1694B1 (en) 1992-08-09
EG19937A (en) 2000-12-31
PT97836B (pt) 1998-11-30
SK164491A3 (en) 1995-07-11
KR100212411B1 (en) 1999-08-02
AP9100270A0 (en) 1991-07-31
LV10292B (en) 1995-08-20
DK0535048T3 (da) 1997-09-29
AU651979B2 (en) 1994-08-11
LTIP1736A (en) 1995-08-25
TW221712B (sh) 1994-03-11
SE9001985D0 (sv) 1990-06-01
AP207A (en) 1992-08-18
BG61165B1 (bg) 1997-01-31
HU9203774D0 (en) 1993-03-29
HRP920771A2 (en) 1997-04-30
HRP920771B1 (en) 1999-10-31
DE69125489T2 (de) 1997-08-14
YU95191A (sh) 1994-06-10
SG48078A1 (en) 1998-04-17
IL98273A0 (en) 1992-06-21
BG97123A (bg) 1993-12-24
MA22166A1 (fr) 1991-12-31
PH30761A (en) 1997-10-17
WO1991018923A1 (en) 1991-12-12
CZ164491A3 (cs) 1999-07-14

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Expiry date: 20110601