SK279675B6 - Trisubstituované bifenyly, spôsob ich výroby, lieč - Google Patents
Trisubstituované bifenyly, spôsob ich výroby, lieč Download PDFInfo
- Publication number
- SK279675B6 SK279675B6 SK1169-93A SK116993A SK279675B6 SK 279675 B6 SK279675 B6 SK 279675B6 SK 116993 A SK116993 A SK 116993A SK 279675 B6 SK279675 B6 SK 279675B6
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- general formula
- carbon atoms
- trisubstituted
- mmol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4235933 | 1992-10-23 | ||
| DE4319041A DE4319041A1 (de) | 1992-10-23 | 1993-06-08 | Trisubstituierte Biphenyle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK116993A3 SK116993A3 (en) | 1994-11-09 |
| SK279675B6 true SK279675B6 (sk) | 1999-02-11 |
Family
ID=25919778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1169-93A SK279675B6 (sk) | 1992-10-23 | 1993-10-22 | Trisubstituované bifenyly, spôsob ich výroby, lieč |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US5596006A (cs) |
| EP (1) | EP0594019B1 (cs) |
| JP (1) | JPH06199838A (cs) |
| KR (1) | KR100304225B1 (cs) |
| CN (1) | CN1040435C (cs) |
| AT (1) | ATE189893T1 (cs) |
| AU (1) | AU670315B2 (cs) |
| CA (1) | CA2108814A1 (cs) |
| CZ (1) | CZ283482B6 (cs) |
| DE (2) | DE4319041A1 (cs) |
| DK (1) | DK0594019T3 (cs) |
| ES (1) | ES2145021T3 (cs) |
| FI (1) | FI934646A7 (cs) |
| GR (1) | GR3033207T3 (cs) |
| HU (1) | HUT65819A (cs) |
| IL (1) | IL107333A (cs) |
| MX (1) | MX9306419A (cs) |
| NO (1) | NO304651B1 (cs) |
| NZ (1) | NZ250002A (cs) |
| PT (1) | PT594019E (cs) |
| SK (1) | SK279675B6 (cs) |
| TW (1) | TW248555B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4319040A1 (de) * | 1992-10-23 | 1994-04-28 | Bayer Ag | Alkoxymethylsubstituierte Pyridonbiphenyle |
| EP1310488A4 (en) * | 2000-08-09 | 2005-08-10 | Mitsubishi Pharma Corp | CONDENSED BICYCLIC AMIDE COMPOUNDS AND MEDICAL USES THEREOF |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| EP1465869B1 (en) * | 2001-12-21 | 2013-05-15 | Exelixis Patent Company LLC | Modulators of lxr |
| ES2251292B1 (es) * | 2004-04-20 | 2007-07-01 | Inke, S.A. | Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis. |
| WO2006130901A1 (en) * | 2005-06-07 | 2006-12-14 | Bayer Healthcare Ag | Control of metabolic abnormalities |
| DE102005030522A1 (de) * | 2005-06-30 | 2007-01-04 | Bayer Healthcare Ag | Salz des Embusartans |
| TWI448284B (zh) | 2007-04-24 | 2014-08-11 | Theravance Inc | 雙效抗高血壓劑 |
| DE102007028407A1 (de) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007028319A1 (de) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007028406A1 (de) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007028320A1 (de) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| EP2138178A1 (en) | 2008-06-28 | 2009-12-30 | Bayer Schering Pharma Aktiengesellschaft | Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma |
| SI2847228T1 (sl) | 2012-05-10 | 2018-11-30 | Bayer Pharma Aktiengesellschaft | Protitelesa zmožna vezave na faktor koagulacije XI in/ali njeno aktivirano obliko faktor XIa in njihove uporabe |
| KR102614588B1 (ko) | 2018-08-20 | 2023-12-18 | 삼성디스플레이 주식회사 | 표시 장치의 제조 방법 |
| WO2024159724A1 (zh) * | 2023-02-03 | 2024-08-08 | 科莱博(江苏)科技股份有限公司 | 一种邻联苯基噁唑啉化合物及其合成方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
| GB8911854D0 (en) * | 1989-05-23 | 1989-07-12 | Ici Plc | Heterocyclic compounds |
| IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
| CA2018443A1 (en) * | 1989-06-14 | 1990-12-14 | Joseph A. Finkelstein | Imidazolyl-alkenoic acids |
| DE10075018I2 (de) * | 1989-06-14 | 2001-08-09 | Smithkline Beecham Corp | Imidazoalkensäure. |
| US5164407A (en) * | 1989-07-03 | 1992-11-17 | Merck & Co., Inc. | Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists |
| EP0485410A1 (en) * | 1989-07-06 | 1992-05-20 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern | A detector for monitoring low molecular weight compounds |
| CA2027937A1 (en) * | 1989-10-25 | 1991-04-26 | Richard M. Keenan | Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles |
| WO1991009697A1 (en) * | 1989-12-25 | 1991-07-11 | Nippon Steel Corporation | Sheet of titanium-aluminum intermetallic compound and process for producing the same |
| EP0453210A3 (en) * | 1990-04-19 | 1993-01-13 | Imperial Chemical Industries Plc | Pyridine derivatives |
| CN1034934C (zh) * | 1990-06-19 | 1997-05-21 | 明治制果株式会社 | 血管紧张素ii拮抗性吡啶衍生物的制备方法 |
| US5250548A (en) * | 1990-09-10 | 1993-10-05 | Abbott Laboratories | Angiotensin II receptor antagonists |
| IL100917A0 (en) * | 1991-02-16 | 1992-11-15 | Fisons Plc | Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them |
| CN1068109A (zh) * | 1991-02-16 | 1993-01-20 | 菲索斯有限公司 | 新的血管紧张肽ii拮抗剂及其制剂的制备和应用 |
| DE4221583A1 (de) * | 1991-11-12 | 1993-05-13 | Bayer Ag | Substituierte biphenylpyridone |
| ATE250043T1 (de) * | 1991-11-18 | 2003-10-15 | Du Pont | Tetrazolylphenylborsäureintermediate zur synthese von aii rezeptor antagonisten |
| US5130439A (en) * | 1991-11-18 | 1992-07-14 | Lo Young S | Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists |
| US5206374A (en) * | 1991-11-18 | 1993-04-27 | E. I. Du Pont De Nemours And Company | Process for preparing tetrazolylphenylboronic acid intermediates |
| US5310928A (en) * | 1991-11-18 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Process for preparing biphenyltetrazole compounds |
| DE4319040A1 (de) * | 1992-10-23 | 1994-04-28 | Bayer Ag | Alkoxymethylsubstituierte Pyridonbiphenyle |
-
1993
- 1993-06-08 DE DE4319041A patent/DE4319041A1/de not_active Withdrawn
- 1993-09-22 AU AU47541/93A patent/AU670315B2/en not_active Ceased
- 1993-10-06 TW TW082108238A patent/TW248555B/zh active
- 1993-10-07 NO NO933591A patent/NO304651B1/no not_active IP Right Cessation
- 1993-10-11 DE DE59309956T patent/DE59309956D1/de not_active Expired - Fee Related
- 1993-10-11 PT PT93116404T patent/PT594019E/pt unknown
- 1993-10-11 DK DK93116404T patent/DK0594019T3/da active
- 1993-10-11 AT AT93116404T patent/ATE189893T1/de active
- 1993-10-11 EP EP93116404A patent/EP0594019B1/de not_active Expired - Lifetime
- 1993-10-11 ES ES93116404T patent/ES2145021T3/es not_active Expired - Lifetime
- 1993-10-15 MX MX9306419A patent/MX9306419A/es not_active IP Right Cessation
- 1993-10-20 NZ NZ250002A patent/NZ250002A/en unknown
- 1993-10-20 CZ CZ932217A patent/CZ283482B6/cs not_active IP Right Cessation
- 1993-10-20 IL IL107333A patent/IL107333A/en not_active IP Right Cessation
- 1993-10-20 CA CA002108814A patent/CA2108814A1/en not_active Abandoned
- 1993-10-21 FI FI934646A patent/FI934646A7/fi unknown
- 1993-10-22 HU HU9302997A patent/HUT65819A/hu unknown
- 1993-10-22 JP JP5286167A patent/JPH06199838A/ja active Pending
- 1993-10-22 KR KR1019930021987A patent/KR100304225B1/ko not_active Expired - Fee Related
- 1993-10-22 SK SK1169-93A patent/SK279675B6/sk unknown
- 1993-10-22 CN CN93118766A patent/CN1040435C/zh not_active Expired - Fee Related
-
1995
- 1995-01-03 US US08/368,252 patent/US5596006A/en not_active Expired - Fee Related
- 1995-12-18 US US08/574,082 patent/US5863930A/en not_active Expired - Fee Related
-
2000
- 2000-04-12 GR GR20000400901T patent/GR3033207T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ250002A (en) | 1995-03-28 |
| AU4754193A (en) | 1994-05-05 |
| DK0594019T3 (da) | 2000-07-03 |
| ATE189893T1 (de) | 2000-03-15 |
| CA2108814A1 (en) | 1994-04-24 |
| AU670315B2 (en) | 1996-07-11 |
| PT594019E (pt) | 2000-08-31 |
| KR100304225B1 (ko) | 2004-05-10 |
| CZ283482B6 (cs) | 1998-04-15 |
| DE59309956D1 (de) | 2000-03-30 |
| EP0594019B1 (de) | 2000-02-23 |
| HUT65819A (en) | 1994-07-28 |
| GR3033207T3 (en) | 2000-08-31 |
| US5596006A (en) | 1997-01-21 |
| IL107333A (en) | 1998-01-04 |
| MX9306419A (es) | 1994-05-31 |
| NO304651B1 (no) | 1999-01-25 |
| FI934646L (fi) | 1994-04-24 |
| KR940009174A (ko) | 1994-05-20 |
| TW248555B (cs) | 1995-06-01 |
| CZ221793A3 (en) | 1994-05-18 |
| IL107333A0 (en) | 1994-01-25 |
| CN1040435C (zh) | 1998-10-28 |
| EP0594019A1 (de) | 1994-04-27 |
| US5863930A (en) | 1999-01-26 |
| JPH06199838A (ja) | 1994-07-19 |
| FI934646A0 (fi) | 1993-10-21 |
| CN1089260A (zh) | 1994-07-13 |
| FI934646A7 (fi) | 1994-04-24 |
| DE4319041A1 (de) | 1994-04-28 |
| HU9302997D0 (en) | 1994-01-28 |
| SK116993A3 (en) | 1994-11-09 |
| NO933591L (no) | 1994-04-25 |
| NO933591D0 (no) | 1993-10-07 |
| ES2145021T3 (es) | 2000-07-01 |
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