NO304651B1 - Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler - Google Patents

Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler

Info

Publication number
NO304651B1
NO304651B1 NO933591A NO933591A NO304651B1 NO 304651 B1 NO304651 B1 NO 304651B1 NO 933591 A NO933591 A NO 933591A NO 933591 A NO933591 A NO 933591A NO 304651 B1 NO304651 B1 NO 304651B1
Authority
NO
Norway
Prior art keywords
drugs
blood pressure
stands
pressure tanks
trisubstituted biphenyls
Prior art date
Application number
NO933591A
Other languages
English (en)
Norwegian (no)
Other versions
NO933591D0 (no
NO933591L (no
Inventor
J Rgen Dressel
Peter Fey
Rudolf Hanko
Bsch Walter H
Thomas Kromer
Ller Ulrich E M
Ller-Gliemann Matthias M
Martin Beuck
Stanislav Kazda
Stefan Wohlfeil
Andreas Knorr
Johannes-Peter Stasch
Siegfried Zaiss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO933591D0 publication Critical patent/NO933591D0/no
Publication of NO933591L publication Critical patent/NO933591L/no
Publication of NO304651B1 publication Critical patent/NO304651B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
NO933591A 1992-10-23 1993-10-07 Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler NO304651B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4235933 1992-10-23
DE4319041A DE4319041A1 (de) 1992-10-23 1993-06-08 Trisubstituierte Biphenyle

Publications (3)

Publication Number Publication Date
NO933591D0 NO933591D0 (no) 1993-10-07
NO933591L NO933591L (no) 1994-04-25
NO304651B1 true NO304651B1 (no) 1999-01-25

Family

ID=25919778

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933591A NO304651B1 (no) 1992-10-23 1993-10-07 Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler

Country Status (22)

Country Link
US (2) US5596006A (cs)
EP (1) EP0594019B1 (cs)
JP (1) JPH06199838A (cs)
KR (1) KR100304225B1 (cs)
CN (1) CN1040435C (cs)
AT (1) ATE189893T1 (cs)
AU (1) AU670315B2 (cs)
CA (1) CA2108814A1 (cs)
CZ (1) CZ283482B6 (cs)
DE (2) DE4319041A1 (cs)
DK (1) DK0594019T3 (cs)
ES (1) ES2145021T3 (cs)
FI (1) FI934646L (cs)
GR (1) GR3033207T3 (cs)
HU (1) HUT65819A (cs)
IL (1) IL107333A (cs)
MX (1) MX9306419A (cs)
NO (1) NO304651B1 (cs)
NZ (1) NZ250002A (cs)
PT (1) PT594019E (cs)
SK (1) SK279675B6 (cs)
TW (1) TW248555B (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4319040A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Alkoxymethylsubstituierte Pyridonbiphenyle
AU2001277731A1 (en) 2000-08-09 2002-02-18 Welfide Corporation Fused bicyclic amide compounds and medicinal use thereof
EP1465869B1 (en) * 2001-12-21 2013-05-15 Exelixis Patent Company LLC Modulators of lxr
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
ES2251292B1 (es) * 2004-04-20 2007-07-01 Inke, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis.
WO2006130901A1 (en) * 2005-06-07 2006-12-14 Bayer Healthcare Ag Control of metabolic abnormalities
DE102005030522A1 (de) * 2005-06-30 2007-01-04 Bayer Healthcare Ag Salz des Embusartans
TWI448284B (zh) 2007-04-24 2014-08-11 Theravance Inc 雙效抗高血壓劑
DE102007028407A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028320A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028406A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
EP2138178A1 (en) 2008-06-28 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
US9783614B2 (en) 2012-05-10 2017-10-10 Bayer Pharma Aktiengesellschaft Antibodies capable of binding to the coagulation Factor XI and/or its activated form factor Xia and uses thereof
KR102614588B1 (ko) 2018-08-20 2023-12-18 삼성디스플레이 주식회사 표시 장치의 제조 방법
WO2024159724A1 (zh) * 2023-02-03 2024-08-08 科莱博(江苏)科技股份有限公司 一种邻联苯基噁唑啉化合物及其合成方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
DK0955294T3 (da) * 1989-06-14 2004-02-02 Smithkline Beecham Corp Imidazolylalkensyre
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
WO1991001001A1 (en) * 1989-07-06 1991-01-24 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland A detector for monitoring low molecular weight compounds
AU640417B2 (en) * 1989-10-25 1993-08-26 Smithkline Beecham Corporation Substituted 5-((tetrazolyl)alkenyl)imidazoles
EP0460234B1 (en) * 1989-12-25 1997-05-02 Nippon Steel Corporation Sheet of titanium-aluminum intermetallic compound and process for producing the same
GB2244054B (en) * 1990-04-19 1994-04-06 Ici Plc Pyridine derivatives
KR100196559B1 (ko) * 1990-06-19 1999-06-15 기따사또 이찌로 안지오텐신ii 길항작용을 함유하는 피리딘 유도체
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
CN1068109A (zh) * 1991-02-16 1993-01-20 菲索斯有限公司 新的血管紧张肽ii拮抗剂及其制剂的制备和应用
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
DE4221583A1 (de) * 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
US5130439A (en) * 1991-11-18 1992-07-14 Lo Young S Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
SK280887B6 (sk) * 1991-11-18 2000-09-12 E. I. Du Pont De Nemours And Company Spôsob výroby tetrazolylbifenylových zlúčenín a medziprodukty tohto spôsobu
DE4319040A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Alkoxymethylsubstituierte Pyridonbiphenyle

Also Published As

Publication number Publication date
KR940009174A (ko) 1994-05-20
IL107333A0 (en) 1994-01-25
IL107333A (en) 1998-01-04
ES2145021T3 (es) 2000-07-01
NO933591D0 (no) 1993-10-07
CN1040435C (zh) 1998-10-28
EP0594019B1 (de) 2000-02-23
CZ283482B6 (cs) 1998-04-15
TW248555B (cs) 1995-06-01
US5596006A (en) 1997-01-21
GR3033207T3 (en) 2000-08-31
NZ250002A (en) 1995-03-28
EP0594019A1 (de) 1994-04-27
ATE189893T1 (de) 2000-03-15
JPH06199838A (ja) 1994-07-19
FI934646A7 (fi) 1994-04-24
DE4319041A1 (de) 1994-04-28
US5863930A (en) 1999-01-26
CN1089260A (zh) 1994-07-13
DK0594019T3 (da) 2000-07-03
PT594019E (pt) 2000-08-31
NO933591L (no) 1994-04-25
CZ221793A3 (en) 1994-05-18
CA2108814A1 (en) 1994-04-24
KR100304225B1 (ko) 2004-05-10
DE59309956D1 (de) 2000-03-30
SK116993A3 (en) 1994-11-09
HU9302997D0 (en) 1994-01-28
AU4754193A (en) 1994-05-05
MX9306419A (es) 1994-05-31
FI934646L (fi) 1994-04-24
SK279675B6 (sk) 1999-02-11
FI934646A0 (fi) 1993-10-21
HUT65819A (en) 1994-07-28
AU670315B2 (en) 1996-07-11

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN APRIL 2002