SK279516B6 - Substituované deriváty pyrimidínu, spôsob ich výro - Google Patents

Substituované deriváty pyrimidínu, spôsob ich výro Download PDF

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Publication number
SK279516B6
SK279516B6 SK32-95A SK3295A SK279516B6 SK 279516 B6 SK279516 B6 SK 279516B6 SK 3295 A SK3295 A SK 3295A SK 279516 B6 SK279516 B6 SK 279516B6
Authority
SK
Slovakia
Prior art keywords
hydrogen
group
formula
general formula
atom
Prior art date
Application number
SK32-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK3295A3 (en
Inventor
David Munro
Royston Davis
Janet A. Day
Jacqueline A. Wilkin
William W. Wood
Original Assignee
Shell Internationale Research Maatschappij B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shell Internationale Research Maatschappij B.V. filed Critical Shell Internationale Research Maatschappij B.V.
Publication of SK3295A3 publication Critical patent/SK3295A3/sk
Publication of SK279516B6 publication Critical patent/SK279516B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/58Two sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK32-95A 1992-07-17 1993-07-15 Substituované deriváty pyrimidínu, spôsob ich výro SK279516B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92306600 1992-07-17
PCT/EP1993/001880 WO1994002470A1 (en) 1992-07-17 1993-07-15 Pesticidal pyrimidine compounds

Publications (2)

Publication Number Publication Date
SK3295A3 SK3295A3 (en) 1995-05-10
SK279516B6 true SK279516B6 (sk) 1998-12-02

Family

ID=8211436

Family Applications (1)

Application Number Title Priority Date Filing Date
SK32-95A SK279516B6 (sk) 1992-07-17 1993-07-15 Substituované deriváty pyrimidínu, spôsob ich výro

Country Status (27)

Country Link
US (1) US5707995A (hu)
EP (1) EP0650482B1 (hu)
JP (1) JP3353895B2 (hu)
KR (1) KR950702541A (hu)
CN (1) CN1087085A (hu)
AT (1) ATE206404T1 (hu)
AU (1) AU671845B2 (hu)
CA (1) CA2140346A1 (hu)
CZ (1) CZ282275B6 (hu)
DE (1) DE69330882T2 (hu)
DK (1) DK0650482T3 (hu)
EG (1) EG20267A (hu)
ES (1) ES2164666T3 (hu)
GE (1) GEP19981224B (hu)
HU (1) HUT70086A (hu)
IL (1) IL106324A (hu)
MD (1) MD1154F2 (hu)
OA (1) OA10124A (hu)
PL (6) PL173056B1 (hu)
PT (1) PT650482E (hu)
RU (1) RU95105445A (hu)
SG (1) SG49712A1 (hu)
SK (1) SK279516B6 (hu)
TR (1) TR26781A (hu)
TW (1) TW234077B (hu)
WO (1) WO1994002470A1 (hu)
ZA (1) ZA935155B (hu)

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DE3364860D1 (en) 1982-04-07 1986-09-04 Nat Res Dev Endoprosthetic bone joint devices
US6235887B1 (en) 1991-11-26 2001-05-22 Isis Pharmaceuticals, Inc. Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines
GB9325217D0 (en) * 1993-12-09 1994-02-09 Zeneca Ltd Pyrimidine derivatives
CZ290330B6 (cs) * 1995-01-26 2002-07-17 American Cyanamid Company 2,6-Disubstituované pyridinové a 2,4-disubstituované pyrimidinové deriváty, způsob a meziprodukty pro jejich výrobu, jejich pouľití a herbicidní prostředky na jejich bázi a způsob potlačování růstu neľádoucích rostlin
EP0723960B1 (en) * 1995-01-26 2003-04-02 Basf Aktiengesellschaft Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines
US5849758A (en) * 1995-05-30 1998-12-15 American Cyanamid Company Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines
WO1996028427A1 (en) 1995-03-10 1996-09-19 Berlex Laboratories, Inc. Benzamidine derivatives their preparation and their use as anti-coagulants
US5994375A (en) * 1996-02-12 1999-11-30 Berlex Laboratories, Inc. Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants
SG63694A1 (en) * 1996-03-07 1999-03-30 American Cyanamid Co Process for the preparation of unsymmetrical 4,6-bis (aryloxy) pyrimidine compounds
WO1997036878A1 (fr) * 1996-03-29 1997-10-09 Ube Industries, Ltd. Composes de pyrimidine, procede de production de ces composes et bactericides pour l'agriculture et l'horticulture
EP0929547B1 (en) 1996-09-12 2002-11-27 Schering Aktiengesellschaft Benzamidine derivatives substituted by cyclic amino acid or cycl ic hydroxy acid derivatives and their use as anti-coagulants
US6004985A (en) 1996-10-09 1999-12-21 Berlex Laboratories, Inc. Thio acid derived monocylic N-heterocyclics as anticoagulants
DE19710609A1 (de) * 1997-03-14 1998-09-17 Bayer Ag Substituierte Aminosalicylsäureamide
AU7452998A (en) * 1997-05-28 1998-12-30 Nippon Soda Co., Ltd. Pyrimidine compounds, process for producing the same, and pesticides
US5883104A (en) * 1997-06-12 1999-03-16 American Cyanamid Company Methods for improving the residual control of mites and prolonging the protection of plants from mites infestations
US5849910A (en) * 1997-09-05 1998-12-15 American Cyanamid Company Process for the preparation of unsymmetrical 4,6-bis aryloxy-pyrimidine compounds
US6686364B2 (en) 1997-12-08 2004-02-03 Berlex Laboratories, Inc. Benzamidine derivatives and their use as anti-coagulants
ES2361146T3 (es) 1998-03-27 2011-06-14 Janssen Pharmaceutica Nv Derivados de la piramidina inhibitatoria de vih.
US6087498A (en) * 1998-05-12 2000-07-11 American Cyanamid Company Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds
ATE205835T1 (de) * 1998-07-14 2001-10-15 Basf Ag Akarizid und insektizid wirksame, substituierte pyrimidine und verfahren zu ihrer herstellung
CA2277719A1 (en) * 1998-07-14 2000-01-14 American Cyanamid Company Parasitic and saprophagous mite control on beneficial insects
US6342499B1 (en) 1998-07-14 2002-01-29 Basf Aktiengesellschaft Parasitic and saprophagous mite control in beneficial insects
US6281219B1 (en) 1998-07-14 2001-08-28 American Cyanamid Co. Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof
US6262088B1 (en) 1998-11-19 2001-07-17 Berlex Laboratories, Inc. Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants
US6127376A (en) * 1998-12-04 2000-10-03 Berlex Laboratories, Inc. Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
WO2000049001A2 (en) * 1999-02-16 2000-08-24 E.I. Du Pont De Nemours And Company Phenoxy-, phenylthio-, phenylamino-, benzyloxy-, benzylthio- or benzylaminopyrimidine insectidices and acaricides
CO5210940A1 (es) * 1999-05-04 2002-10-30 Novartis Ag Compuestos plaguicidas derivados de pirimidina y composiciones que los contienen
WO2000071536A1 (en) * 1999-05-20 2000-11-30 E.I. Du Pont De Nemours And Company Heteroaryloxypyrimidine insecticides and acaricides
US6350761B1 (en) 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
CZ300712B6 (cs) 1999-09-24 2009-07-22 Janssen Pharmaceutica N. V. Cásticová farmaceutická kompozice, pevná disperze a farmaceutická dávková forma, zpusoby jejich prípravy a použití a obchodní balení s jejich obsahem
US6906067B2 (en) * 1999-12-28 2005-06-14 Bristol-Myers Squibb Company N-heterocyclic inhibitors of TNF-α expression
DE10013914A1 (de) 2000-03-21 2001-09-27 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
DE10014607A1 (de) 2000-03-24 2001-09-27 Bayer Ag Verfahren zur Herstellung von unsymmetrischen 4,6-Bis(aryloxy pyrimidin-Derivaten
DE10055941A1 (de) 2000-11-10 2002-05-23 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
WO2005047268A2 (en) * 2003-11-10 2005-05-26 X-Ceptor Therapeutics, Inc. Substituted pyrimidine compositions and methods of use
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
EP1574502A1 (en) * 2004-03-08 2005-09-14 Novartis AG Use of pyrimidine compounds in the preparation of parasiticides
MX2009000802A (es) * 2006-07-21 2009-02-03 Novartis Ag Compuestos organicos.
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
WO2012000922A2 (en) * 2010-06-28 2012-01-05 Novartis Ag New Use
JP2015083541A (ja) * 2012-02-03 2015-04-30 アグロカネショウ株式会社 対称性4,6−ビス(アリールオキシ)ピリミジン化合物の製造方法
CN105777653A (zh) 2014-12-26 2016-07-20 中国科学院上海药物研究所 用作Lp-PLA2抑制剂的嘧啶酮类化合物及其药物组合物
CN106008368A (zh) * 2016-06-22 2016-10-12 连云港笃翔化工有限公司 2, 4, 6-三氯嘧啶一锅法合成2-烃巯基-4, 6-二烃氧基嘧啶类化合物及其制备方法
CN109721548B (zh) * 2017-10-31 2020-11-13 南通泰禾化工股份有限公司 一种嘧菌酯的制备方法
CN109824603B (zh) * 2017-11-23 2021-03-12 浙江省化工研究院有限公司 一种嘧啶胺类化合物、其制备方法及应用

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GB8903019D0 (en) * 1989-02-10 1989-03-30 Ici Plc Fungicides
US5145856A (en) * 1989-02-10 1992-09-08 Imperial Chemical Industries Plc Fungicides

Also Published As

Publication number Publication date
PL173467B1 (pl) 1998-03-31
HUT70086A (en) 1995-09-28
PT650482E (pt) 2002-03-28
JP3353895B2 (ja) 2002-12-03
PL173091B1 (pl) 1998-01-30
TW234077B (hu) 1994-11-11
US5707995A (en) 1998-01-13
PL307131A1 (en) 1995-05-02
AU4570093A (en) 1994-02-14
CZ282275B6 (cs) 1997-06-11
PL173021B1 (pl) 1998-01-30
RU95105445A (ru) 1996-10-27
DE69330882T2 (de) 2002-04-11
MD950235A (ro) 1997-10-31
ATE206404T1 (de) 2001-10-15
SK3295A3 (en) 1995-05-10
PL173066B1 (pl) 1998-01-30
IL106324A (en) 1998-09-24
JPH07508999A (ja) 1995-10-05
PL173056B1 (pl) 1998-01-30
EP0650482A1 (en) 1995-05-03
DE69330882D1 (de) 2001-11-08
CA2140346A1 (en) 1994-02-03
KR950702541A (ko) 1995-07-29
OA10124A (en) 1996-12-18
SG49712A1 (en) 1998-06-15
MD1154F2 (ro) 1999-02-28
CN1087085A (zh) 1994-05-25
DK0650482T3 (da) 2001-12-03
IL106324A0 (en) 1993-11-15
GEP19981224B (en) 1998-02-11
AU671845B2 (en) 1996-09-12
CZ3095A3 (en) 1995-09-13
ZA935155B (en) 1994-06-20
ES2164666T3 (es) 2002-03-01
EG20267A (en) 1998-05-31
TR26781A (tr) 1995-05-15
EP0650482B1 (en) 2001-10-04
PL173717B1 (pl) 1998-04-30
WO1994002470A1 (en) 1994-02-03

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