RU95105445A - Пиримидиновые соединения, способ их получения, пестицидная композиция, способы борьбы с вредителями - Google Patents
Пиримидиновые соединения, способ их получения, пестицидная композиция, способы борьбы с вредителямиInfo
- Publication number
- RU95105445A RU95105445A RU95105445/04A RU95105445A RU95105445A RU 95105445 A RU95105445 A RU 95105445A RU 95105445/04 A RU95105445/04 A RU 95105445/04A RU 95105445 A RU95105445 A RU 95105445A RU 95105445 A RU95105445 A RU 95105445A
- Authority
- RU
- Russia
- Prior art keywords
- hydrogen
- alkyl
- halogen
- alkoxy
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/58—Two sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Пиримидиновые соединения формулы (1) в которой Xи Xкаждый представляют кислород; S(O), при n = 0,1 или 2; или СО, CHили NR, при R являющимся водородом или алкилом, Rи Rкаждый является водородом или галогеном, Rи Rкаждый является водородом, галогеном, циано, нитро, алкилом, галоалкилом, алкокси, алкилтио, амино, моно- или ди-алкиламино, алкоксиалкилом, галоалкоксиалкилом или алкоксикарбонилом, Rи Rкаждый представляет водород, хлор, алкил, галоалкил, галоалкенил, галоалкинил, галоалкокси, галоалкоксикарбонил, галоалкилтио, галоалкоксиалкил, галоалкилсульфинил или галоалкилсульфонил, нитро или циано; Rи Rкаждый представляет водород, галоген, алкил или алкокси; Rпредставляет водород, галоген, циано, алкил, галоалкил, алкокси, алкилтио, алкилсульфинил или финил; и Rявляется водородом или, когда Rпредставляет водород, алкилом; при условии, что либо каждый фенил является незамещенным либо по крайней мере один из Rи Rне является водородом, обладающие полезной пестицидной активностью, а также способ его получения.
Claims (1)
- Пиримидиновые соединения формулы (1) в которой X1 и X2 каждый представляют кислород; S(O)n, при n = 0,1 или 2; или СО, CH2 или NR, при R являющимся водородом или алкилом, R1 и R10 каждый является водородом или галогеном, R2 и R9 каждый является водородом, галогеном, циано, нитро, алкилом, галоалкилом, алкокси, алкилтио, амино, моно- или ди-алкиламино, алкоксиалкилом, галоалкоксиалкилом или алкоксикарбонилом, R3 и R8 каждый представляет водород, хлор, алкил, галоалкил, галоалкенил, галоалкинил, галоалкокси, галоалкоксикарбонил, галоалкилтио, галоалкоксиалкил, галоалкилсульфинил или галоалкилсульфонил, нитро или циано; R4 и R7 каждый представляет водород, галоген, алкил или алкокси; R5 представляет водород, галоген, циано, алкил, галоалкил, алкокси, алкилтио, алкилсульфинил или финил; и R6 является водородом или, когда R5 представляет водород, алкилом; при условии, что либо каждый фенил является незамещенным либо по крайней мере один из R3 и R8 не является водородом, обладающие полезной пестицидной активностью, а также способ его получения.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92306600.5 | 1992-07-17 | ||
| EP92306600 | 1992-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU95105445A true RU95105445A (ru) | 1996-10-27 |
Family
ID=8211436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU95105445/04A RU95105445A (ru) | 1992-07-17 | 1993-07-15 | Пиримидиновые соединения, способ их получения, пестицидная композиция, способы борьбы с вредителями |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5707995A (ru) |
| EP (1) | EP0650482B1 (ru) |
| JP (1) | JP3353895B2 (ru) |
| KR (1) | KR950702541A (ru) |
| CN (1) | CN1087085A (ru) |
| AT (1) | ATE206404T1 (ru) |
| AU (1) | AU671845B2 (ru) |
| CA (1) | CA2140346A1 (ru) |
| CZ (1) | CZ282275B6 (ru) |
| DE (1) | DE69330882T2 (ru) |
| DK (1) | DK0650482T3 (ru) |
| EG (1) | EG20267A (ru) |
| ES (1) | ES2164666T3 (ru) |
| GE (1) | GEP19981224B (ru) |
| HU (1) | HUT70086A (ru) |
| IL (1) | IL106324A (ru) |
| MD (1) | MD1154F2 (ru) |
| OA (1) | OA10124A (ru) |
| PL (6) | PL173021B1 (ru) |
| PT (1) | PT650482E (ru) |
| RU (1) | RU95105445A (ru) |
| SG (1) | SG49712A1 (ru) |
| SK (1) | SK279516B6 (ru) |
| TR (1) | TR26781A (ru) |
| TW (1) | TW234077B (ru) |
| WO (1) | WO1994002470A1 (ru) |
| ZA (1) | ZA935155B (ru) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3364860D1 (en) | 1982-04-07 | 1986-09-04 | Nat Res Dev | Endoprosthetic bone joint devices |
| US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
| GB9325217D0 (en) * | 1993-12-09 | 1994-02-09 | Zeneca Ltd | Pyrimidine derivatives |
| EP0723960B1 (en) * | 1995-01-26 | 2003-04-02 | Basf Aktiengesellschaft | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines |
| US5849758A (en) * | 1995-05-30 | 1998-12-15 | American Cyanamid Company | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines |
| CZ290330B6 (cs) * | 1995-01-26 | 2002-07-17 | American Cyanamid Company | 2,6-Disubstituované pyridinové a 2,4-disubstituované pyrimidinové deriváty, způsob a meziprodukty pro jejich výrobu, jejich pouľití a herbicidní prostředky na jejich bázi a způsob potlačování růstu neľádoucích rostlin |
| DK0813525T3 (da) | 1995-03-10 | 2004-02-16 | Berlex Lab | Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter |
| US5994375A (en) | 1996-02-12 | 1999-11-30 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants |
| UA53611C2 (ru) * | 1996-03-07 | 2003-02-17 | Амерікан Ціанамід Компані | Способ получения несиметричных 4,6-бис(арилокси)пиримидиновых соединений |
| EP0894791A4 (en) * | 1996-03-29 | 2001-07-11 | Ube Industries | PYRIMIDINE COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF AND BACTERICIDES FOR AGRICULTURE AND HORTICULTURE |
| CZ86199A3 (cs) | 1996-09-12 | 1999-08-11 | Schering Aktiengesellschaft | Benzamidinové deriváty substituované cyklickou aminokyselinou a cyklické hydrokyselinové deriváty, farmaceutický prostředek obsahující tyto látky a jejich použití jako protisrážecích činidel |
| US6004985A (en) * | 1996-10-09 | 1999-12-21 | Berlex Laboratories, Inc. | Thio acid derived monocylic N-heterocyclics as anticoagulants |
| DE19710609A1 (de) * | 1997-03-14 | 1998-09-17 | Bayer Ag | Substituierte Aminosalicylsäureamide |
| WO1998054154A1 (fr) * | 1997-05-28 | 1998-12-03 | Nippon Soda Co., Ltd. | Composes de pyrimidine, leur procede de production et pesticides |
| US5883104A (en) * | 1997-06-12 | 1999-03-16 | American Cyanamid Company | Methods for improving the residual control of mites and prolonging the protection of plants from mites infestations |
| US5849910A (en) * | 1997-09-05 | 1998-12-15 | American Cyanamid Company | Process for the preparation of unsymmetrical 4,6-bis aryloxy-pyrimidine compounds |
| US6686364B2 (en) | 1997-12-08 | 2004-02-03 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| DE69943247D1 (de) | 1998-03-27 | 2011-04-14 | Janssen Pharmaceutica Nv | HIV hemmende Pyrimidin Derivate |
| US6087498A (en) * | 1998-05-12 | 2000-07-11 | American Cyanamid Company | Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds |
| US6342499B1 (en) | 1998-07-14 | 2002-01-29 | Basf Aktiengesellschaft | Parasitic and saprophagous mite control in beneficial insects |
| CA2277719A1 (en) * | 1998-07-14 | 2000-01-14 | American Cyanamid Company | Parasitic and saprophagous mite control on beneficial insects |
| US6281219B1 (en) | 1998-07-14 | 2001-08-28 | American Cyanamid Co. | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof |
| EP0972770B1 (en) * | 1998-07-14 | 2001-09-19 | Basf Aktiengesellschaft | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof |
| US6262088B1 (en) | 1998-11-19 | 2001-07-17 | Berlex Laboratories, Inc. | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants |
| US6127376A (en) * | 1998-12-04 | 2000-10-03 | Berlex Laboratories, Inc. | Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants |
| AU3357700A (en) * | 1999-02-16 | 2000-09-04 | E.I. Du Pont De Nemours And Company | Phenoxypyrimidine insecticides and acaricides |
| CO5210940A1 (es) * | 1999-05-04 | 2002-10-30 | Novartis Ag | Compuestos plaguicidas derivados de pirimidina y composiciones que los contienen |
| AU5020400A (en) * | 1999-05-20 | 2000-12-12 | E.I. Du Pont De Nemours And Company | Heteroaryloxypyrimidine insecticides and acaricides |
| US6350761B1 (en) | 1999-07-30 | 2002-02-26 | Berlex Laboratories, Inc. | Benzenamine derivatives as anti-coagulants |
| JP4919566B2 (ja) | 1999-09-24 | 2012-04-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 抗ウイルス組成物 |
| US6906067B2 (en) * | 1999-12-28 | 2005-06-14 | Bristol-Myers Squibb Company | N-heterocyclic inhibitors of TNF-α expression |
| DE10013914A1 (de) | 2000-03-21 | 2001-09-27 | Bayer Ag | Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften |
| DE10014607A1 (de) | 2000-03-24 | 2001-09-27 | Bayer Ag | Verfahren zur Herstellung von unsymmetrischen 4,6-Bis(aryloxy pyrimidin-Derivaten |
| DE10055941A1 (de) | 2000-11-10 | 2002-05-23 | Bayer Ag | Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften |
| WO2005047268A2 (en) * | 2003-11-10 | 2005-05-26 | X-Ceptor Therapeutics, Inc. | Substituted pyrimidine compositions and methods of use |
| DE10353281A1 (de) | 2003-11-14 | 2005-06-16 | Bayer Cropscience Ag | Wirkstoffkombination mit insektiziden und akariziden Eigenschaften |
| EP1574502A1 (en) * | 2004-03-08 | 2005-09-14 | Novartis AG | Use of pyrimidine compounds in the preparation of parasiticides |
| CN101495462B (zh) * | 2006-07-21 | 2012-03-21 | 诺瓦提斯公司 | 嘧啶衍生物及其作为杀虫剂的用途 |
| DE102007045922A1 (de) | 2007-09-26 | 2009-04-02 | Bayer Cropscience Ag | Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften |
| WO2012000922A2 (en) * | 2010-06-28 | 2012-01-05 | Novartis Ag | New Use |
| JP2015083541A (ja) * | 2012-02-03 | 2015-04-30 | アグロカネショウ株式会社 | 対称性４，６−ビス（アリールオキシ）ピリミジン化合物の製造方法 |
| CN105777653A (zh) * | 2014-12-26 | 2016-07-20 | 中国科学院上海药物研究所 | 用作Lp-PLA2抑制剂的嘧啶酮类化合物及其药物组合物 |
| CN106008368A (zh) * | 2016-06-22 | 2016-10-12 | 连云港笃翔化工有限公司 | 2, 4, 6-三氯嘧啶一锅法合成2-烃巯基-4, 6-二烃氧基嘧啶类化合物及其制备方法 |
| CN109721548B (zh) * | 2017-10-31 | 2020-11-13 | 南通泰禾化工股份有限公司 | 一种嘧菌酯的制备方法 |
| CN109824603B (zh) * | 2017-11-23 | 2021-03-12 | 浙江省化工研究院有限公司 | 一种嘧啶胺类化合物、其制备方法及应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5145856A (en) * | 1989-02-10 | 1992-09-08 | Imperial Chemical Industries Plc | Fungicides |
| GB8903019D0 (en) * | 1989-02-10 | 1989-03-30 | Ici Plc | Fungicides |
-
1993
- 1993-07-13 IL IL10632493A patent/IL106324A/en unknown
- 1993-07-13 TW TW082105581A patent/TW234077B/zh active
- 1993-07-15 PL PL93307131A patent/PL173021B1/pl unknown
- 1993-07-15 KR KR1019950700201A patent/KR950702541A/ko not_active Application Discontinuation
- 1993-07-15 WO PCT/EP1993/001880 patent/WO1994002470A1/en active IP Right Grant
- 1993-07-15 AT AT93915936T patent/ATE206404T1/de not_active IP Right Cessation
- 1993-07-15 RU RU95105445/04A patent/RU95105445A/ru unknown
- 1993-07-15 ES ES93915936T patent/ES2164666T3/es not_active Expired - Lifetime
- 1993-07-15 AU AU45700/93A patent/AU671845B2/en not_active Ceased
- 1993-07-15 JP JP50413894A patent/JP3353895B2/ja not_active Expired - Fee Related
- 1993-07-15 PL PL93317720A patent/PL173467B1/pl unknown
- 1993-07-15 CZ CZ9530A patent/CZ282275B6/cs unknown
- 1993-07-15 SK SK32-95A patent/SK279516B6/sk unknown
- 1993-07-15 EG EG44493A patent/EG20267A/xx active
- 1993-07-15 CA CA002140346A patent/CA2140346A1/en not_active Abandoned
- 1993-07-15 DE DE69330882T patent/DE69330882T2/de not_active Expired - Fee Related
- 1993-07-15 HU HU9500127A patent/HUT70086A/hu unknown
- 1993-07-15 SG SG1996004295A patent/SG49712A1/en unknown
- 1993-07-15 PL PL93317716A patent/PL173066B1/pl unknown
- 1993-07-15 MD MD95-0235A patent/MD1154F2/ru unknown
- 1993-07-15 EP EP93915936A patent/EP0650482B1/en not_active Expired - Lifetime
- 1993-07-15 PL PL93317717A patent/PL173717B1/pl unknown
- 1993-07-15 PT PT93915936T patent/PT650482E/pt unknown
- 1993-07-15 PL PL93317719A patent/PL173056B1/pl unknown
- 1993-07-15 DK DK93915936T patent/DK0650482T3/da active
- 1993-07-15 US US08/351,477 patent/US5707995A/en not_active Expired - Fee Related
- 1993-07-15 GE GEAP19932333A patent/GEP19981224B/en unknown
- 1993-07-15 PL PL93317718A patent/PL173091B1/pl unknown
- 1993-07-16 ZA ZA935155A patent/ZA935155B/xx unknown
- 1993-07-16 CN CN93116763A patent/CN1087085A/zh active Pending
- 1993-07-19 TR TR93/0604A patent/TR26781A/xx unknown
-
1995
- 1995-01-12 OA OA60603A patent/OA10124A/en unknown
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