SK278794B6 - 2-hydroxyetylaminosubstituované deriváty 5,11-diox - Google Patents

2-hydroxyetylaminosubstituované deriváty 5,11-diox Download PDF

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Publication number
SK278794B6
SK278794B6 SK2669-91A SK266991A SK278794B6 SK 278794 B6 SK278794 B6 SK 278794B6 SK 266991 A SK266991 A SK 266991A SK 278794 B6 SK278794 B6 SK 278794B6
Authority
SK
Slovakia
Prior art keywords
indeno
dioxo
dihydro
isoquinoline
tumor
Prior art date
Application number
SK2669-91A
Other languages
English (en)
Slovak (sk)
Other versions
SK266991A3 (en
Inventor
Ji�� Michalsk�
Ji�� Hrbata
Ji�� K�Epelka
Milan M�Lka
Milan Miko
Milan Hrub�
Milan Ferenc
Eva Sk�Celov�
Irena Kejhov�
RَEna Reichlov�
Anna Kargerov�
Jitka �Ediv�
Alois Koloni�N�
Josef Urbanec
Original Assignee
V�Fb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by V�Fb filed Critical V�Fb
Publication of SK278794B6 publication Critical patent/SK278794B6/sk
Publication of SK266991A3 publication Critical patent/SK266991A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
SK2669-91A 1991-08-29 1991-08-29 2-hydroxyethylaminosubstituted derivatives of 5,11-dioxo-5,6- -dihydro-11h-indeno£1,2-c|isoquinoline, a process for manufacture thereof and pharmaceutical composition containing the same SK266991A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS912669A CZ281473B6 (cs) 1991-08-29 1991-08-29 Deriváty 6-/X-(2-hydroxyethyl)aminoalkyl/-5,11 -dioxo-5,6-dihydro-11H-indeno/1,2-c/-isochinolinu a způsob jejich výroby

Publications (2)

Publication Number Publication Date
SK278794B6 true SK278794B6 (sk) 1998-03-04
SK266991A3 SK266991A3 (en) 1998-03-04

Family

ID=5364459

Family Applications (1)

Application Number Title Priority Date Filing Date
SK2669-91A SK266991A3 (en) 1991-08-29 1991-08-29 2-hydroxyethylaminosubstituted derivatives of 5,11-dioxo-5,6- -dihydro-11h-indeno£1,2-c|isoquinoline, a process for manufacture thereof and pharmaceutical composition containing the same

Country Status (15)

Country Link
EP (1) EP0643699B1 (fr)
JP (1) JPH07500581A (fr)
AT (1) ATE144499T1 (fr)
AU (1) AU663729B2 (fr)
CA (1) CA2116680A1 (fr)
CZ (1) CZ281473B6 (fr)
DE (1) DE69214842T2 (fr)
DK (1) DK0643699T3 (fr)
FI (1) FI107256B (fr)
HU (1) HU217551B (fr)
NO (1) NO180194C (fr)
PL (1) PL169572B1 (fr)
RU (1) RU2120939C1 (fr)
SK (1) SK266991A3 (fr)
WO (1) WO1993005023A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
US6509344B1 (en) * 1998-10-14 2003-01-21 The United States Of America As Represented By The Department Of Health And Human Services Indenoisoquinolines as antineoplastic agents
US6956035B2 (en) 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
WO2005009398A2 (fr) * 2003-02-28 2005-02-03 Inotek Pharmaceuticals Corporation Derives de benzamide tetracyclique et leurs procedes d'utilisation
BRPI0508233A (pt) 2004-02-26 2007-07-17 Inotek Pharmaceuticals Corp derivados de isoquinolina e métodos para emprego destes
RU2007135362A (ru) 2005-02-25 2009-03-27 Инотек Фармасьютикалз Корпорейшн (Us) Тетрациклические амино- и карбоксамидосоединения и способ их применения
CA2620052A1 (fr) 2005-08-24 2007-03-01 Inotek Pharmaceuticals Corporation Analogues d'indenoisoquinolinone et leurs procedes d'utilisation
AU2008221358A1 (en) 2007-02-28 2008-09-04 Inotek Pharmaceuticals Corporation Indenoisoquinolinone analogs and methods of use thereof
CN102250000A (zh) * 2010-05-17 2011-11-23 中国人民解放军第二军医大学 茚并喹啉酮类化合物及其制备方法和用途
TWI642658B (zh) * 2017-11-01 2018-12-01 國立臺灣師範大學 茚並異喹啉衍生物的製備方法

Also Published As

Publication number Publication date
ATE144499T1 (de) 1996-11-15
FI940895A0 (fi) 1994-02-25
NO180194B (no) 1996-11-25
DK0643699T3 (da) 1997-04-28
AU663729B2 (en) 1995-10-19
FI940895A (fi) 1994-02-25
JPH07500581A (ja) 1995-01-19
EP0643699A1 (fr) 1995-03-22
HU9400563D0 (en) 1994-05-30
FI107256B (fi) 2001-06-29
SK266991A3 (en) 1998-03-04
CA2116680A1 (fr) 1993-03-18
DE69214842T2 (de) 1997-02-27
DE69214842D1 (de) 1996-11-28
CZ266991A3 (en) 1993-03-17
NO940542D0 (no) 1994-02-17
HU217551B (hu) 2000-02-28
WO1993005023A1 (fr) 1993-03-18
HUT70396A (en) 1995-10-30
NO940542L (no) 1994-02-17
CZ281473B6 (cs) 1996-10-16
PL169572B1 (pl) 1996-08-30
EP0643699B1 (fr) 1996-10-23
RU2120939C1 (ru) 1998-10-27
NO180194C (no) 1997-03-05
AU2583592A (en) 1993-04-05

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