NO940542D0 - 6-[X-(2-hydroksyetyl)aminoalkylÅ-5,11-diokso-5,6-dihydro-11-H-indeno[1,2-cÅisokinoliner og anvendelse derav som antineoplastiske midler - Google Patents

6-[X-(2-hydroksyetyl)aminoalkylÅ-5,11-diokso-5,6-dihydro-11-H-indeno[1,2-cÅisokinoliner og anvendelse derav som antineoplastiske midler

Info

Publication number
NO940542D0
NO940542D0 NO940542A NO940542A NO940542D0 NO 940542 D0 NO940542 D0 NO 940542D0 NO 940542 A NO940542 A NO 940542A NO 940542 A NO940542 A NO 940542A NO 940542 D0 NO940542 D0 NO 940542D0
Authority
NO
Norway
Prior art keywords
indeno
derivatives
dioxo
dihydro
hydroxyethyl
Prior art date
Application number
NO940542A
Other languages
English (en)
Other versions
NO180194C (no
NO180194B (no
NO940542L (no
Inventor
Jiri Michalsky
Jiri Hrbata
Jiri Krepelka
Milan Melka
Milan Miko
Milan Hruby
Milan Ferenc
Eva Skacelova
Irena Kejhova
Rozena Reichlova
Anna Kargerova
Jitka Sediva
Original Assignee
Vyzk Ustav Farm Biochem Sp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vyzk Ustav Farm Biochem Sp filed Critical Vyzk Ustav Farm Biochem Sp
Publication of NO940542L publication Critical patent/NO940542L/no
Publication of NO940542D0 publication Critical patent/NO940542D0/no
Publication of NO180194B publication Critical patent/NO180194B/no
Publication of NO180194C publication Critical patent/NO180194C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO940542A 1991-08-29 1994-02-17 6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner NO180194C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS912669A CZ281473B6 (cs) 1991-08-29 1991-08-29 Deriváty 6-/X-(2-hydroxyethyl)aminoalkyl/-5,11 -dioxo-5,6-dihydro-11H-indeno/1,2-c/-isochinolinu a způsob jejich výroby
PCT/CS1992/000026 WO1993005023A1 (en) 1991-08-29 1992-08-27 6((2-hydroxyethyl)amino alkyl)-5,11-dioxo-5,6-dihydro-11-h-indeno(1,2-c)isoquinoline and their use as antineoplastic agents

Publications (4)

Publication Number Publication Date
NO940542L NO940542L (no) 1994-02-17
NO940542D0 true NO940542D0 (no) 1994-02-17
NO180194B NO180194B (no) 1996-11-25
NO180194C NO180194C (no) 1997-03-05

Family

ID=5364459

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940542A NO180194C (no) 1991-08-29 1994-02-17 6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner

Country Status (15)

Country Link
EP (1) EP0643699B1 (no)
JP (1) JPH07500581A (no)
AT (1) ATE144499T1 (no)
AU (1) AU663729B2 (no)
CA (1) CA2116680A1 (no)
CZ (1) CZ281473B6 (no)
DE (1) DE69214842T2 (no)
DK (1) DK0643699T3 (no)
FI (1) FI107256B (no)
HU (1) HU217551B (no)
NO (1) NO180194C (no)
PL (1) PL169572B1 (no)
RU (1) RU2120939C1 (no)
SK (1) SK266991A3 (no)
WO (1) WO1993005023A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
WO2000021537A1 (en) * 1998-10-14 2000-04-20 Purdue Research Foundation Novel indenoisoquinolines as antineoplastic agents
US6956035B2 (en) 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
AU2004258801A1 (en) * 2003-02-28 2005-02-03 Inotek Pharmaceuticals Corporation Tetracyclic Benzamide Derivatives and methods of use thereof
EP1722797A4 (en) 2004-02-26 2008-03-19 Inotek Pharmaceuticals Corp ISOCHINOLINE DERIVATIVES AND METHOD FOR THE APPLICATION THEREOF
KR20070116011A (ko) 2005-02-25 2007-12-06 이노텍 파마슈티컬스 코포레이션 테트라사이클릭 아미노 및 카복사미도 화합물 및 이의 이용방법
JP2009506060A (ja) 2005-08-24 2009-02-12 イノテック ファーマシューティカルズ コーポレイション インデノイソキノリノン類縁体及びそれらの使用方法
CA2677046A1 (en) 2007-02-28 2008-09-04 Inotek Pharmaceuticals Corporation Indenoisoquinolinone analogs and methods of use thereof
CN102250000A (zh) * 2010-05-17 2011-11-23 中国人民解放军第二军医大学 茚并喹啉酮类化合物及其制备方法和用途
TWI642658B (zh) * 2017-11-01 2018-12-01 國立臺灣師範大學 茚並異喹啉衍生物的製備方法

Also Published As

Publication number Publication date
FI940895A (fi) 1994-02-25
CA2116680A1 (en) 1993-03-18
HUT70396A (en) 1995-10-30
SK278794B6 (sk) 1998-03-04
CZ281473B6 (cs) 1996-10-16
EP0643699B1 (en) 1996-10-23
HU217551B (hu) 2000-02-28
JPH07500581A (ja) 1995-01-19
DE69214842T2 (de) 1997-02-27
AU2583592A (en) 1993-04-05
WO1993005023A1 (en) 1993-03-18
HU9400563D0 (en) 1994-05-30
DE69214842D1 (de) 1996-11-28
DK0643699T3 (da) 1997-04-28
NO180194C (no) 1997-03-05
NO180194B (no) 1996-11-25
EP0643699A1 (en) 1995-03-22
PL169572B1 (pl) 1996-08-30
CZ266991A3 (en) 1993-03-17
RU2120939C1 (ru) 1998-10-27
NO940542L (no) 1994-02-17
SK266991A3 (en) 1998-03-04
FI107256B (fi) 2001-06-29
ATE144499T1 (de) 1996-11-15
FI940895A0 (fi) 1994-02-25
AU663729B2 (en) 1995-10-19

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