FI940895A0 - 6-(X-(2-hydroksietyyli)aminoalkyyli)-5,11-diokso-5,6-dihydro-11-H-indeno(1,2-c)isokinoliinit ja niiden käyttö kasvainten vastaisina aineina - Google Patents

6-(X-(2-hydroksietyyli)aminoalkyyli)-5,11-diokso-5,6-dihydro-11-H-indeno(1,2-c)isokinoliinit ja niiden käyttö kasvainten vastaisina aineina

Info

Publication number
FI940895A0
FI940895A0 FI940895A FI940895A FI940895A0 FI 940895 A0 FI940895 A0 FI 940895A0 FI 940895 A FI940895 A FI 940895A FI 940895 A FI940895 A FI 940895A FI 940895 A0 FI940895 A0 FI 940895A0
Authority
FI
Finland
Prior art keywords
indeno
derivatives
dioxo
dihydro
hydroxyethyl
Prior art date
Application number
FI940895A
Other languages
English (en)
Swedish (sv)
Other versions
FI107256B (fi
FI940895A (fi
Inventor
Jiri Michalsky
Jiri Hrbata
Jiri Krepelka
Milan Melka
Milan Miko
Milan Hruby
Milan Ferenc
Eva Skacelova
Irena Kejhova
Ruzena Reichlova
Anna Kargerova
Jitka Sediva
Alois Kolonicny
Josef Urbanec
Original Assignee
Vyzk Ustav Farm Biochem Sp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vyzk Ustav Farm Biochem Sp filed Critical Vyzk Ustav Farm Biochem Sp
Publication of FI940895A publication Critical patent/FI940895A/fi
Publication of FI940895A0 publication Critical patent/FI940895A0/fi
Application granted granted Critical
Publication of FI107256B publication Critical patent/FI107256B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI940895A 1991-08-29 1994-02-25 Menetelmä kasvainten vastaisten 6-(2-hydroksietyyliamino) tai 6-[(2-hydroksietyyli)aminoalkyyli] -5,11-diokso-5,6-dihydro-11-H-indeno(1,2-c)isokinoliinien valmistamiseksi FI107256B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CS912669A CZ281473B6 (cs) 1991-08-29 1991-08-29 Deriváty 6-/X-(2-hydroxyethyl)aminoalkyl/-5,11 -dioxo-5,6-dihydro-11H-indeno/1,2-c/-isochinolinu a způsob jejich výroby
CS266991 1991-08-29
CS9200026 1992-08-27
PCT/CS1992/000026 WO1993005023A1 (en) 1991-08-29 1992-08-27 6((2-hydroxyethyl)amino alkyl)-5,11-dioxo-5,6-dihydro-11-h-indeno(1,2-c)isoquinoline and their use as antineoplastic agents

Publications (3)

Publication Number Publication Date
FI940895A FI940895A (fi) 1994-02-25
FI940895A0 true FI940895A0 (fi) 1994-02-25
FI107256B FI107256B (fi) 2001-06-29

Family

ID=5364459

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940895A FI107256B (fi) 1991-08-29 1994-02-25 Menetelmä kasvainten vastaisten 6-(2-hydroksietyyliamino) tai 6-[(2-hydroksietyyli)aminoalkyyli] -5,11-diokso-5,6-dihydro-11-H-indeno(1,2-c)isokinoliinien valmistamiseksi

Country Status (15)

Country Link
EP (1) EP0643699B1 (fi)
JP (1) JPH07500581A (fi)
AT (1) ATE144499T1 (fi)
AU (1) AU663729B2 (fi)
CA (1) CA2116680A1 (fi)
CZ (1) CZ281473B6 (fi)
DE (1) DE69214842T2 (fi)
DK (1) DK0643699T3 (fi)
FI (1) FI107256B (fi)
HU (1) HU217551B (fi)
NO (1) NO180194C (fi)
PL (1) PL169572B1 (fi)
RU (1) RU2120939C1 (fi)
SK (1) SK278794B6 (fi)
WO (1) WO1993005023A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
CA2347100C (en) * 1998-10-14 2010-12-14 Purdue Research Foundation Novel indenoisoquinolines as antineoplastic agents
US6956035B2 (en) 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
CA2517260A1 (en) * 2003-02-28 2005-02-03 Inotek Pharmaceuticals Corporation Tetracyclic benzamide derivatives and methods of use thereof
US20050228007A1 (en) 2004-02-26 2005-10-13 Prakash Jagtap Isoquinoline derivatives and methods of use thereof
CN101137377A (zh) 2005-02-25 2008-03-05 伊诺泰克制药公司 四环氨基和甲酰胺基化合物及其用法
EP1937268A4 (en) 2005-08-24 2009-07-22 Inotek Pharmaceuticals Corp INDENOISOQUINOLINONE ANALOGUES AND METHODS OF USE
AU2008221358A1 (en) 2007-02-28 2008-09-04 Inotek Pharmaceuticals Corporation Indenoisoquinolinone analogs and methods of use thereof
CN102250000A (zh) * 2010-05-17 2011-11-23 中国人民解放军第二军医大学 茚并喹啉酮类化合物及其制备方法和用途
TWI642658B (zh) * 2017-11-01 2018-12-01 國立臺灣師範大學 茚並異喹啉衍生物的製備方法

Also Published As

Publication number Publication date
DE69214842D1 (de) 1996-11-28
SK266991A3 (en) 1998-03-04
AU663729B2 (en) 1995-10-19
PL169572B1 (pl) 1996-08-30
NO940542L (no) 1994-02-17
FI107256B (fi) 2001-06-29
RU2120939C1 (ru) 1998-10-27
NO180194B (no) 1996-11-25
FI940895A (fi) 1994-02-25
NO180194C (no) 1997-03-05
DE69214842T2 (de) 1997-02-27
WO1993005023A1 (en) 1993-03-18
AU2583592A (en) 1993-04-05
HU9400563D0 (en) 1994-05-30
NO940542D0 (no) 1994-02-17
DK0643699T3 (da) 1997-04-28
CZ281473B6 (cs) 1996-10-16
ATE144499T1 (de) 1996-11-15
SK278794B6 (sk) 1998-03-04
EP0643699B1 (en) 1996-10-23
CZ266991A3 (en) 1993-03-17
HU217551B (hu) 2000-02-28
EP0643699A1 (en) 1995-03-22
HUT70396A (en) 1995-10-30
CA2116680A1 (en) 1993-03-18
JPH07500581A (ja) 1995-01-19

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