SK27598A3 - Piperazine derivatives and process for the preparation thereof - Google Patents
Piperazine derivatives and process for the preparation thereof Download PDFInfo
- Publication number
- SK27598A3 SK27598A3 SK275-98A SK27598A SK27598A3 SK 27598 A3 SK27598 A3 SK 27598A3 SK 27598 A SK27598 A SK 27598A SK 27598 A3 SK27598 A3 SK 27598A3
- Authority
- SK
- Slovakia
- Prior art keywords
- ome
- substituted
- unsubstituted
- piperazine
- methoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR19960025825 | 1996-06-29 | ||
| KR19960025826 | 1996-06-29 | ||
| KR19960025827 | 1996-06-29 | ||
| KR19960040596 | 1996-09-18 | ||
| KR1019970022985A KR100204319B1 (ko) | 1996-06-29 | 1997-06-03 | 신규 피페라진 유도체 및 그 제조방법 |
| KR1019970022984A KR100204320B1 (ko) | 1996-06-29 | 1997-06-03 | 신규 피페라진 유도체 및 그 제조방법 |
| KR1019970023192A KR100204318B1 (ko) | 1996-06-29 | 1997-06-04 | 신규 피페라진 유도체 및 그 제조방법 |
| KR1019970023193A KR100197111B1 (ko) | 1996-09-18 | 1997-06-04 | 신규 피페라진 유도체 및 그 제조방법 |
| PCT/KR1997/000128 WO1998000402A1 (en) | 1996-06-29 | 1997-06-28 | Piperazine derivatives and process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK27598A3 true SK27598A3 (en) | 1998-11-04 |
Family
ID=27573799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK275-98A SK27598A3 (en) | 1996-06-29 | 1997-06-28 | Piperazine derivatives and process for the preparation thereof |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6028195A (ru) |
| EP (1) | EP0850222B1 (ru) |
| JP (1) | JP3032303B2 (ru) |
| CN (1) | CN1152015C (ru) |
| AT (1) | ATE241600T1 (ru) |
| AU (1) | AU713171B2 (ru) |
| BG (1) | BG102286A (ru) |
| CA (1) | CA2230960C (ru) |
| CZ (1) | CZ59398A3 (ru) |
| DE (1) | DE69722360T2 (ru) |
| NO (1) | NO311616B1 (ru) |
| NZ (1) | NZ329847A (ru) |
| PL (1) | PL325341A1 (ru) |
| RU (1) | RU2146254C1 (ru) |
| SK (1) | SK27598A3 (ru) |
| TR (1) | TR199800371T1 (ru) |
| WO (1) | WO1998000402A1 (ru) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE384048T1 (de) | 1998-09-22 | 2008-02-15 | Astellas Pharma Inc | Cyanophenyl-derivate |
| US20020065296A1 (en) | 1999-01-13 | 2002-05-30 | Bayer Corporation | Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors |
| ATE556713T1 (de) | 1999-01-13 | 2012-05-15 | Bayer Healthcare Llc | Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer |
| CA2549558C (en) | 1999-01-13 | 2010-08-31 | Bayer Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| KR100396738B1 (ko) * | 1999-03-03 | 2003-09-03 | 삼진제약주식회사 | 피페라진 유도체 및 그 제조방법 |
| IL153884A0 (en) * | 2000-07-20 | 2003-07-31 | Neurogen Corp | Capsaicin receptor ligands |
| DE10035928A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| DE10035927A1 (de) * | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| DE10035908A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| US7183050B2 (en) | 2001-04-18 | 2007-02-27 | Krull Ulrich J | Gradient resolved information platform |
| JP4583760B2 (ja) | 2002-02-01 | 2010-11-17 | ユーロ−セルティーク エス．エイ． | 疼痛の治療に有用な治療薬 |
| JP4621502B2 (ja) * | 2002-06-28 | 2011-01-26 | ユーロ−セルティーク エス．エイ． | 疼痛の治療に有用な治療剤 |
| NZ537916A (en) * | 2002-06-29 | 2005-11-25 | Zentaris Gmbh | Aryl- and heteroarylcarbonylpiperazines and their use for the treatment of benign and malignant diseases |
| US7262194B2 (en) * | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US7157462B2 (en) * | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US20050130989A1 (en) * | 2003-01-28 | 2005-06-16 | Aventis Pharma S. A. | N-arylheteroaromatic products compositions containing them and use thereof |
| JP2006516656A (ja) * | 2003-01-28 | 2006-07-06 | アヴェンティス ファーマ エス．エー． | Ｎ−アリールヘテロ芳香族物質、それを含む組成物およびその用途 |
| PT1636585E (pt) | 2003-05-20 | 2008-03-27 | Bayer Pharmaceuticals Corp | Diarilureias com actividade inibidora de cinase |
| JP6097946B2 (ja) * | 2004-11-17 | 2017-03-22 | レクサン ファーマシューティカルズ インコーポレイテッド | １−［（６，７−置換−アルコキシキノキサリニル）アミノカルボニル］−４−（ヘテロ）アリールピペラジン誘導体 |
| WO2007020888A1 (ja) | 2005-08-12 | 2007-02-22 | Takeda Pharmaceutical Company Limited | 脳・神経細胞保護剤および睡眠障害治療薬 |
| US20090068146A1 (en) | 2005-10-31 | 2009-03-12 | Scott Wilhelm | Diaryl ureas and combinations |
| WO2009048101A1 (ja) * | 2007-10-10 | 2009-04-16 | Takeda Pharmaceutical Company Limited | アミド化合物 |
| US7946206B2 (en) * | 2007-11-21 | 2011-05-24 | Rocksmart, Llc | Quick-release system |
| TWI434842B (zh) * | 2008-07-14 | 2014-04-21 | Astellas Pharma Inc | Azole compounds |
| WO2014127350A1 (en) * | 2013-02-18 | 2014-08-21 | The Scripps Research Institute | Modulators of vasopressin receptors with therapeutic potential |
| WO2017136727A2 (en) | 2016-02-05 | 2017-08-10 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| ES2912295T3 (es) | 2016-12-09 | 2022-05-25 | Denali Therapeutics Inc | Compuestos útiles como inhibidores de RIPK1 |
| TW202334164A (zh) | 2022-01-12 | 2023-09-01 | 美商戴納立製藥公司 | （Ｓ）－５－苄基－Ｎ－（５－甲基－４－側氧基－２，３，４，５－四氫吡啶並［３，２－ｂ］［１，４］氧氮呯－３－基）－４Ｈ－１，２，４－三唑－３－甲醯胺的晶型 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| OA04700A (fr) * | 1973-05-15 | 1980-07-31 | Rhone Poulenc Sa | Nouveaux dérivés de la naphtyridine et leur procédé de préparation. |
| US4038391A (en) * | 1973-05-15 | 1977-07-26 | Rhone-Poulenc S.A. | 6-(1,8-Naphthyridin-2-yl)-5-piperazino carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo-[3,4-b]pyrazines and related pyridines |
| US4016274A (en) * | 1973-05-15 | 1977-04-05 | Rhone-Poulenc S.A. | Naphthyridine derivatives |
| JPS63115167A (ja) * | 1986-10-31 | 1988-05-19 | Konica Corp | ハロゲン化銀写真感光材料 |
| US5391571A (en) * | 1989-11-15 | 1995-02-21 | American Home Products Corporation | Cholesterol ester hydrolase inhibitors |
| DE4018070A1 (de) * | 1990-06-06 | 1991-12-12 | Bayer Ag | Morpholinoharnstoff-derivate |
| ZA929008B (en) * | 1991-12-13 | 1993-05-21 | Bristol Myers Squibb Co | Piperazinyl- and piperidinyl-cyclohexanols. |
| DE4216364A1 (de) * | 1991-12-14 | 1993-11-25 | Thomae Gmbh Dr K | Neue Pyridylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5461047A (en) * | 1993-06-16 | 1995-10-24 | G. D. Searle & Co. | 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
| FR2722788B1 (fr) * | 1994-07-20 | 1996-10-04 | Pf Medicament | Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant |
| US5780472A (en) * | 1995-01-11 | 1998-07-14 | Samjin Pharmaceuticazl Co., Ltd. | Piperazine derivatives and methods for the preparation thereof and compositions containing the same |
-
1997
- 1997-06-28 US US09/029,660 patent/US6028195A/en not_active Expired - Lifetime
- 1997-06-28 TR TR1998/00371T patent/TR199800371T1/xx unknown
- 1997-06-28 DE DE69722360T patent/DE69722360T2/de not_active Expired - Lifetime
- 1997-06-28 AT AT97930868T patent/ATE241600T1/de not_active IP Right Cessation
- 1997-06-28 CA CA002230960A patent/CA2230960C/en not_active Expired - Lifetime
- 1997-06-28 WO PCT/KR1997/000128 patent/WO1998000402A1/en not_active Application Discontinuation
- 1997-06-28 JP JP10504004A patent/JP3032303B2/ja not_active Expired - Fee Related
- 1997-06-28 AU AU34642/97A patent/AU713171B2/en not_active Expired
- 1997-06-28 PL PL97325341A patent/PL325341A1/xx unknown
- 1997-06-28 RU RU98105684A patent/RU2146254C1/ru active
- 1997-06-28 NZ NZ329847A patent/NZ329847A/xx not_active IP Right Cessation
- 1997-06-28 CZ CZ98593A patent/CZ59398A3/cs unknown
- 1997-06-28 CN CNB971908001A patent/CN1152015C/zh not_active Expired - Lifetime
- 1997-06-28 SK SK275-98A patent/SK27598A3/sk unknown
- 1997-06-28 EP EP97930868A patent/EP0850222B1/en not_active Expired - Lifetime
-
1998
- 1998-02-27 NO NO19980856A patent/NO311616B1/no unknown
- 1998-02-27 BG BG102286A patent/BG102286A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2146254C1 (ru) | 2000-03-10 |
| WO1998000402A1 (en) | 1998-01-08 |
| CN1196724A (zh) | 1998-10-21 |
| EP0850222B1 (en) | 2003-05-28 |
| NO980856D0 (no) | 1998-02-27 |
| JPH11501680A (ja) | 1999-02-09 |
| CA2230960A1 (en) | 1998-01-08 |
| NO311616B1 (no) | 2001-12-17 |
| NZ329847A (en) | 1999-01-28 |
| AU3464297A (en) | 1998-01-21 |
| AU713171B2 (en) | 1999-11-25 |
| NO980856L (no) | 1998-04-27 |
| JP3032303B2 (ja) | 2000-04-17 |
| ATE241600T1 (de) | 2003-06-15 |
| TR199800371T1 (xx) | 1998-06-22 |
| CA2230960C (en) | 2007-08-28 |
| EP0850222A1 (en) | 1998-07-01 |
| US6028195A (en) | 2000-02-22 |
| BG102286A (en) | 1999-08-31 |
| DE69722360D1 (de) | 2003-07-03 |
| CN1152015C (zh) | 2004-06-02 |
| DE69722360T2 (de) | 2003-11-27 |
| CZ59398A3 (cs) | 1998-07-15 |
| PL325341A1 (en) | 1998-07-20 |
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