SK1897A3 - Benzamidines, its preparation, pharmaceutical composition containing them and their use - Google Patents

Benzamidines, its preparation, pharmaceutical composition containing them and their use Download PDF

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Publication number
SK1897A3
SK1897A3 SK18-97A SK1897A SK1897A3 SK 1897 A3 SK1897 A3 SK 1897A3 SK 1897 A SK1897 A SK 1897A SK 1897 A3 SK1897 A3 SK 1897A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
pharmaceutical composition
treatment
phenol
Prior art date
Application number
SK18-97A
Other languages
English (en)
Slovak (sk)
Inventor
Ralf Anderskewitz
Kurt Schromm
Ernst-Otto Renth
Franz Birke
Armin Fugner
Hubert Heuer
Christopher Meade
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of SK1897A3 publication Critical patent/SK1897A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK18-97A 1994-07-13 1995-06-03 Benzamidines, its preparation, pharmaceutical composition containing them and their use SK1897A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4424714A DE4424714A1 (de) 1994-07-13 1994-07-13 Neue chemische Verbindung, ihre Herstellung und ihre Verwendung als Arnzneistoff
PCT/EP1995/002113 WO1996002496A1 (de) 1994-07-13 1995-06-03 Neue chemische verbindung, ihre herstellung und ihre verwendung als arzneistoff

Publications (1)

Publication Number Publication Date
SK1897A3 true SK1897A3 (en) 1997-08-06

Family

ID=6523048

Family Applications (1)

Application Number Title Priority Date Filing Date
SK18-97A SK1897A3 (en) 1994-07-13 1995-06-03 Benzamidines, its preparation, pharmaceutical composition containing them and their use

Country Status (25)

Country Link
US (1) US5686496A (xx)
EP (1) EP0770058A1 (xx)
JP (1) JPH10502646A (xx)
KR (1) KR970704674A (xx)
CN (1) CN1152303A (xx)
AU (1) AU2736895A (xx)
BG (1) BG101104A (xx)
BR (1) BR9508395A (xx)
CA (1) CA2194886A1 (xx)
CO (1) CO4410185A1 (xx)
CZ (1) CZ8297A3 (xx)
DE (1) DE4424714A1 (xx)
EE (1) EE9700065A (xx)
FI (1) FI970095A0 (xx)
HR (1) HRP950363A2 (xx)
HU (1) HUT76827A (xx)
IL (1) IL114572A0 (xx)
MX (1) MX9700245A (xx)
NO (1) NO970123L (xx)
PE (1) PE35196A1 (xx)
PL (1) PL318114A1 (xx)
SK (1) SK1897A3 (xx)
WO (1) WO1996002496A1 (xx)
YU (1) YU45395A (xx)
ZA (1) ZA955781B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486181B1 (en) 1992-08-28 2002-11-26 City Of Hope Human leukocutye 12-lipoxygenase and its role in the pathogenesis of disease states
US6191169B1 (en) 1992-08-28 2001-02-20 City Of Hope Human leukocyte 12-lipoxygenase and its role in the pathogenesis of disease states
EP0743064A1 (en) * 1995-05-17 1996-11-20 Eli Lilly And Company Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease
DE19546452A1 (de) * 1995-12-13 1997-06-19 Boehringer Ingelheim Kg Neue Phenylamidinderivate, Verfahren zu ihrer Herstelung und ihre Verwendung als Arzneimittel
DE19636689A1 (de) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg Neue Benzamidinderivate
DE19718334A1 (de) * 1997-04-30 1998-11-05 Boehringer Ingelheim Pharma Neue Benzylaminderivate und Phenylethylaminderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ID24720A (id) 1997-12-12 2000-08-03 Novartis Ag Senyawa amidino tersubstitusi dalam perawatan penyakit gangguan paru-paru kronis
DE19834713A1 (de) * 1998-07-31 2000-02-03 Boehringer Ingelheim Pharma Neue Phenylethylaminderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6528491B2 (en) * 2000-10-24 2003-03-04 Boehringer Ingelheim Pharma Kg Pyranoside derivatives
WO2002055065A2 (en) * 2001-01-16 2002-07-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of an ltb4 antagonist for the treatment and/or prevention of diseases caused by increased expression of mucin genes
BR0212078A (pt) * 2001-08-31 2004-09-28 Neurochem Int Ltd Método de tratar ou prevenir uma doença relacionada com amilóide em um paciente, composição farmacêutica, composto quìmico, e, uso de um composto
US20070105104A1 (en) * 2003-05-06 2007-05-10 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor ltb4 (ltb4)
US7262223B2 (en) * 2004-01-23 2007-08-28 Neurochem (International) Limited Amidine derivatives for treating amyloidosis
BRPI0513046A (pt) * 2004-07-05 2008-04-22 Dong Wha Pharm Ind Co Ltd composição para prevenção e tratamento de doença inflamatória alérgica
EP1997491B1 (en) * 2004-07-14 2010-09-22 Inflammation Research Center Company Ltd. Method for inhibiting tumor metastasis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0518818A3 (en) * 1991-06-11 1993-04-28 Ciba-Geigy Ag Arylethers, their manufacture and use as medicament
EP0625138B1 (de) * 1992-02-05 1999-06-02 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Neue amidinderivate, ihre herstellung und verwendung als arzneimittel mit ltb4-antagonistischer wirkung

Also Published As

Publication number Publication date
AU2736895A (en) 1996-02-16
KR970704674A (ko) 1997-09-06
CZ8297A3 (en) 1997-09-17
US5686496A (en) 1997-11-11
HUT76827A (en) 1997-11-28
EE9700065A (et) 1997-08-15
EP0770058A1 (de) 1997-05-02
CA2194886A1 (en) 1996-02-01
NO970123D0 (no) 1997-01-10
DE4424714A1 (de) 1996-01-18
PE35196A1 (es) 1996-09-05
MX9700245A (es) 1997-05-31
JPH10502646A (ja) 1998-03-10
IL114572A0 (en) 1995-11-27
HRP950363A2 (en) 1997-08-31
HU9700060D0 (en) 1997-02-28
CN1152303A (zh) 1997-06-18
PL318114A1 (en) 1997-05-12
NO970123L (no) 1997-01-10
BR9508395A (pt) 1997-12-23
ZA955781B (en) 1996-02-22
YU45395A (sh) 1997-12-05
BG101104A (en) 1998-04-30
FI970095A (fi) 1997-01-10
FI970095A0 (fi) 1997-01-10
WO1996002496A1 (de) 1996-02-01
CO4410185A1 (es) 1997-01-09

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