SK140699A3 - Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment - Google Patents

Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment Download PDF

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Publication number
SK140699A3
SK140699A3 SK1406-99A SK140699A SK140699A3 SK 140699 A3 SK140699 A3 SK 140699A3 SK 140699 A SK140699 A SK 140699A SK 140699 A3 SK140699 A3 SK 140699A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
pharmaceutically acceptable
condition
disease
Prior art date
Application number
SK1406-99A
Other languages
English (en)
Slovak (sk)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of SK140699A3 publication Critical patent/SK140699A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1406-99A 1997-05-05 1998-04-28 Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment SK140699A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds
PCT/SE1998/000792 WO1998050380A1 (en) 1997-05-05 1998-04-28 Compounds

Publications (1)

Publication Number Publication Date
SK140699A3 true SK140699A3 (en) 2000-06-12

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1406-99A SK140699A3 (en) 1997-05-05 1998-04-28 Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment

Country Status (28)

Country Link
US (1) US6166030A (es)
EP (1) EP0983266B1 (es)
JP (1) JP2001523263A (es)
KR (1) KR20010012227A (es)
CN (1) CN1255130A (es)
AR (1) AR012602A1 (es)
AT (1) ATE210661T1 (es)
AU (1) AU734394B2 (es)
BR (1) BR9808725A (es)
CA (1) CA2287999A1 (es)
DE (1) DE69802923T2 (es)
DK (1) DK0983266T3 (es)
EE (1) EE9900475A (es)
ES (1) ES2168757T3 (es)
HU (1) HUP0003766A3 (es)
ID (1) ID23156A (es)
IL (1) IL132677A0 (es)
IS (1) IS5237A (es)
MX (1) MXPA99009874A (es)
NO (1) NO995404L (es)
NZ (1) NZ500676A (es)
PL (1) PL336854A1 (es)
PT (1) PT983266E (es)
SE (1) SE9701682D0 (es)
SK (1) SK140699A3 (es)
TR (1) TR199902719T2 (es)
WO (1) WO1998050380A1 (es)
ZA (1) ZA983740B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001024826A2 (en) * 1999-10-06 2001-04-12 The Brigham And Women's Hospital, Inc. Inrease of enos activity through activation of the pi3-kinase/akt pathway by estrogens
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
ZA200709038B (en) 2005-04-13 2009-01-28 Neuraxon Inc Substituted indole compounds having nos inhibitory activity
CL2008000838A1 (es) * 2007-03-23 2008-10-10 Neuraxon Inc Compuestos derivados de quinolina y tetrahidroquinolina, con actividad inhibidora nos; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un dolor de cabeza tal como migrana, dolor cronico, desordenes del sistema nervios
NZ586082A (en) 2007-11-16 2013-03-28 Neuraxon Inc Indole compounds and methods for treating visceral pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504278A (ja) * 1944-06-01 1997-04-28 ザ、ウェルカム、ファンデーション、リミテッド Ｎｏシンターゼインヒビターとしての置換尿素およびイソチオ尿素誘導体
ATE231126T1 (de) * 1993-08-12 2003-02-15 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease- aktivität
ATE177078T1 (de) * 1993-10-21 1999-03-15 Searle & Co Amidino-derivate als no-synthetase inhibitoren
MX9605366A (es) * 1994-05-07 1997-12-31 Astra Ab Derivados de amidina biciclicos como inhibidores de la oxido nitrico sintetasa.
CZ287969B6 (cs) * 1995-08-10 2001-03-14 Astra Pharmaceuticals Limited Amidinový derivát, způsob jeho přípravy, farmaceutický prostředek s jeho obsahem a použití

Also Published As

Publication number Publication date
AU7460098A (en) 1998-11-27
PT983266E (pt) 2002-05-31
EP0983266A1 (en) 2000-03-08
IS5237A (is) 1999-11-01
PL336854A1 (en) 2000-07-17
ID23156A (id) 2000-03-23
DK0983266T3 (da) 2002-03-11
ATE210661T1 (de) 2001-12-15
HUP0003766A2 (en) 2001-03-28
BR9808725A (pt) 2000-07-11
EP0983266B1 (en) 2001-12-12
KR20010012227A (ko) 2001-02-15
ZA983740B (en) 1999-02-19
ES2168757T3 (es) 2002-06-16
AU734394B2 (en) 2001-06-14
AR012602A1 (es) 2000-11-08
MXPA99009874A (es) 2004-09-30
TR199902719T2 (xx) 2000-02-21
NZ500676A (en) 2001-05-25
EE9900475A (et) 2000-06-15
DE69802923D1 (de) 2002-01-24
US6166030A (en) 2000-12-26
JP2001523263A (ja) 2001-11-20
SE9701682D0 (sv) 1997-05-05
WO1998050380A1 (en) 1998-11-12
DE69802923T2 (de) 2002-07-04
CN1255130A (zh) 2000-05-31
IL132677A0 (en) 2001-03-19
NO995404L (no) 2000-01-05
CA2287999A1 (en) 1998-11-12
HUP0003766A3 (en) 2001-09-28
NO995404D0 (no) 1999-11-04

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