PT983266E - Novas tetrahidroisoquinolino tiofenocarboximidamidas - Google Patents

Novas tetrahidroisoquinolino tiofenocarboximidamidas

Info

Publication number
PT983266E
PT983266E PT98921953T PT98921953T PT983266E PT 983266 E PT983266 E PT 983266E PT 98921953 T PT98921953 T PT 98921953T PT 98921953 T PT98921953 T PT 98921953T PT 983266 E PT983266 E PT 983266E
Authority
PT
Portugal
Prior art keywords
tiofenocarboximidamides
tetrahydroisoquinoline
new
new tetrahydroisoquinoline
tetrahydroisoquinoline tiofenocarboximidamides
Prior art date
Application number
PT98921953T
Other languages
English (en)
Portuguese (pt)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT983266E publication Critical patent/PT983266E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT98921953T 1997-05-05 1998-04-28 Novas tetrahidroisoquinolino tiofenocarboximidamidas PT983266E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds

Publications (1)

Publication Number Publication Date
PT983266E true PT983266E (pt) 2002-05-31

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98921953T PT983266E (pt) 1997-05-05 1998-04-28 Novas tetrahidroisoquinolino tiofenocarboximidamidas

Country Status (28)

Country Link
US (1) US6166030A (es)
EP (1) EP0983266B1 (es)
JP (1) JP2001523263A (es)
KR (1) KR20010012227A (es)
CN (1) CN1255130A (es)
AR (1) AR012602A1 (es)
AT (1) ATE210661T1 (es)
AU (1) AU734394B2 (es)
BR (1) BR9808725A (es)
CA (1) CA2287999A1 (es)
DE (1) DE69802923T2 (es)
DK (1) DK0983266T3 (es)
EE (1) EE9900475A (es)
ES (1) ES2168757T3 (es)
HU (1) HUP0003766A3 (es)
ID (1) ID23156A (es)
IL (1) IL132677A0 (es)
IS (1) IS5237A (es)
MX (1) MXPA99009874A (es)
NO (1) NO995404L (es)
NZ (1) NZ500676A (es)
PL (1) PL336854A1 (es)
PT (1) PT983266E (es)
SE (1) SE9701682D0 (es)
SK (1) SK140699A3 (es)
TR (1) TR199902719T2 (es)
WO (1) WO1998050380A1 (es)
ZA (1) ZA983740B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001024826A2 (en) * 1999-10-06 2001-04-12 The Brigham And Women's Hospital, Inc. Inrease of enos activity through activation of the pi3-kinase/akt pathway by estrogens
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
ZA200709038B (en) 2005-04-13 2009-01-28 Neuraxon Inc Substituted indole compounds having nos inhibitory activity
CL2008000838A1 (es) * 2007-03-23 2008-10-10 Neuraxon Inc Compuestos derivados de quinolina y tetrahidroquinolina, con actividad inhibidora nos; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un dolor de cabeza tal como migrana, dolor cronico, desordenes del sistema nervios
NZ586082A (en) 2007-11-16 2013-03-28 Neuraxon Inc Indole compounds and methods for treating visceral pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504278A (ja) * 1944-06-01 1997-04-28 ザ、ウェルカム、ファンデーション、リミテッド Noシンターゼインヒビターとしての置換尿素およびイソチオ尿素誘導体
ATE231126T1 (de) * 1993-08-12 2003-02-15 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease- aktivität
ATE177078T1 (de) * 1993-10-21 1999-03-15 Searle & Co Amidino-derivate als no-synthetase inhibitoren
MX9605366A (es) * 1994-05-07 1997-12-31 Astra Ab Derivados de amidina biciclicos como inhibidores de la oxido nitrico sintetasa.
CZ287969B6 (cs) * 1995-08-10 2001-03-14 Astra Pharmaceuticals Limited Amidinový derivát, způsob jeho přípravy, farmaceutický prostředek s jeho obsahem a použití

Also Published As

Publication number Publication date
AU7460098A (en) 1998-11-27
EP0983266A1 (en) 2000-03-08
IS5237A (is) 1999-11-01
PL336854A1 (en) 2000-07-17
ID23156A (id) 2000-03-23
DK0983266T3 (da) 2002-03-11
ATE210661T1 (de) 2001-12-15
HUP0003766A2 (en) 2001-03-28
BR9808725A (pt) 2000-07-11
EP0983266B1 (en) 2001-12-12
KR20010012227A (ko) 2001-02-15
ZA983740B (en) 1999-02-19
ES2168757T3 (es) 2002-06-16
AU734394B2 (en) 2001-06-14
AR012602A1 (es) 2000-11-08
MXPA99009874A (es) 2004-09-30
TR199902719T2 (xx) 2000-02-21
NZ500676A (en) 2001-05-25
EE9900475A (et) 2000-06-15
DE69802923D1 (de) 2002-01-24
US6166030A (en) 2000-12-26
JP2001523263A (ja) 2001-11-20
SE9701682D0 (sv) 1997-05-05
WO1998050380A1 (en) 1998-11-12
DE69802923T2 (de) 2002-07-04
SK140699A3 (en) 2000-06-12
CN1255130A (zh) 2000-05-31
IL132677A0 (en) 2001-03-19
NO995404L (no) 2000-01-05
CA2287999A1 (en) 1998-11-12
HUP0003766A3 (en) 2001-09-28
NO995404D0 (no) 1999-11-04

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