SE9701682D0 - Compounds - Google Patents

Compounds

Info

Publication number
SE9701682D0
SE9701682D0 SE9701682A SE9701682A SE9701682D0 SE 9701682 D0 SE9701682 D0 SE 9701682D0 SE 9701682 A SE9701682 A SE 9701682A SE 9701682 A SE9701682 A SE 9701682A SE 9701682 D0 SE9701682 D0 SE 9701682D0
Authority
SE
Sweden
Prior art keywords
pct
date
compounds
sec
thienyl
Prior art date
Application number
SE9701682A
Other languages
English (en)
Swedish (sv)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9701682A priority Critical patent/SE9701682D0/xx
Priority to US09/068,944 priority patent/US6166030A/en
Publication of SE9701682D0 publication Critical patent/SE9701682D0/xx
Priority to ARP980101929A priority patent/AR012602A1/es
Priority to SK1406-99A priority patent/SK140699A3/sk
Priority to DK98921953T priority patent/DK0983266T3/da
Priority to ES98921953T priority patent/ES2168757T3/es
Priority to AT98921953T priority patent/ATE210661T1/de
Priority to IL13267798A priority patent/IL132677A0/xx
Priority to PT98921953T priority patent/PT983266E/pt
Priority to EP98921953A priority patent/EP0983266B1/en
Priority to BR9808725-8A priority patent/BR9808725A/pt
Priority to DE69802923T priority patent/DE69802923T2/de
Priority to IDW991285A priority patent/ID23156A/id
Priority to HU0003766A priority patent/HUP0003766A3/hu
Priority to EEP199900475A priority patent/EE9900475A/xx
Priority to MXPA99009874A priority patent/MXPA99009874A/es
Priority to CA002287999A priority patent/CA2287999A1/en
Priority to AU74600/98A priority patent/AU734394B2/en
Priority to PL98336854A priority patent/PL336854A1/xx
Priority to NZ500676A priority patent/NZ500676A/en
Priority to PCT/SE1998/000792 priority patent/WO1998050380A1/en
Priority to CN98804839A priority patent/CN1255130A/zh
Priority to JP54796898A priority patent/JP2001523263A/ja
Priority to KR1019997010176A priority patent/KR20010012227A/ko
Priority to SI9830110T priority patent/SI0983266T1/xx
Priority to TR1999/02719T priority patent/TR199902719T2/xx
Priority to ZA983740A priority patent/ZA983740B/xx
Priority to IS5237A priority patent/IS5237A/is
Priority to NO995404A priority patent/NO995404L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE9701682A 1997-05-05 1997-05-05 Compounds SE9701682D0 (sv)

Priority Applications (29)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds
US09/068,944 US6166030A (en) 1997-05-05 1997-05-05 Compounds
ARP980101929A AR012602A1 (es) 1997-05-05 1998-04-24 Derivados de amidina, formulacion farmaceutica, uso de dichos derivados para la fabricacion de medicamentos y proceso para la preparacion de dichosderivados
TR1999/02719T TR199902719T2 (xx) 1997-05-05 1998-04-28 Bile�ikler.
IDW991285A ID23156A (id) 1997-05-05 1998-04-28 Turunan-turunan amidina, proses pembuatan komposisi dan penggunaannya
CA002287999A CA2287999A1 (en) 1997-05-05 1998-04-28 Compounds
ES98921953T ES2168757T3 (es) 1997-05-05 1998-04-28 Tetrahidroisoquinolin-tiofenocarboximidamidas.
AT98921953T ATE210661T1 (de) 1997-05-05 1998-04-28 Neue tetrahydroiosoquinolin thiophenecarboximidamiden
IL13267798A IL132677A0 (en) 1997-05-05 1998-04-28 Compounds
PT98921953T PT983266E (pt) 1997-05-05 1998-04-28 Novas tetrahidroisoquinolino tiofenocarboximidamidas
EP98921953A EP0983266B1 (en) 1997-05-05 1998-04-28 novel tetrahydroisoquinolin thiophenecarboximidamides
BR9808725-8A BR9808725A (pt) 1997-05-05 1998-04-28 Composto, uso e processo para a preparação do mesmo, formulação farmacêutica, processos de tratamento ou redução do risco de, uma doença ou condição humana em que a inibição da atividade da sintase de óxido nìtrico é benéfica, de tratamento, ou redução do risco, de hipóxia, ou derrame ou isquemia ou condições neurodegenerativas, ou esquizofrenia ou dor ou enxaqueca, ou para a prevenção e reversão da tolerância aos opiatos e diazepinas, ou para o tratamento do vìcio de drogas, de tratamento, ou redução do risco de sofrimento da dor, para o tratamento da doença de parkinson
DE69802923T DE69802923T2 (de) 1997-05-05 1998-04-28 neue tetrahydroiosoquinolin thiophenecarboximidamiden
SK1406-99A SK140699A3 (en) 1997-05-05 1998-04-28 Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment
HU0003766A HUP0003766A3 (en) 1997-05-05 1998-04-28 Isoguinolin derivatives, process for producing them and pharmaceutical compositions containing them
EEP199900475A EE9900475A (et) 1997-05-05 1998-04-28 Ühendid
MXPA99009874A MXPA99009874A (es) 1997-05-05 1998-04-28 Nuevos derivados de amidina.
DK98921953T DK0983266T3 (da) 1997-05-05 1998-04-28 Hidtil ukendte tetrahydrosioquinolinthiophencarboximidamider
AU74600/98A AU734394B2 (en) 1997-05-05 1998-04-28 Compounds
PL98336854A PL336854A1 (en) 1997-05-05 1998-04-28 Chemical compounds
NZ500676A NZ500676A (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
PCT/SE1998/000792 WO1998050380A1 (en) 1997-05-05 1998-04-28 Compounds
CN98804839A CN1255130A (zh) 1997-05-05 1998-04-28 化合物
JP54796898A JP2001523263A (ja) 1997-05-05 1998-04-28 化合物
KR1019997010176A KR20010012227A (ko) 1997-05-05 1998-04-28 화합물
SI9830110T SI0983266T1 (en) 1997-05-05 1998-04-28 novel tetrahydroisoquinolin thiophenecarboximidamides
ZA983740A ZA983740B (en) 1997-05-05 1998-05-04 Novel amidine derivatives and their use in therapy
IS5237A IS5237A (is) 1997-05-05 1999-11-01 Efnasambönd
NO995404A NO995404L (no) 1997-05-05 1999-11-04 Forbindelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds

Publications (1)

Publication Number Publication Date
SE9701682D0 true SE9701682D0 (sv) 1997-05-05

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds

Country Status (28)

Country Link
US (1) US6166030A (xx)
EP (1) EP0983266B1 (xx)
JP (1) JP2001523263A (xx)
KR (1) KR20010012227A (xx)
CN (1) CN1255130A (xx)
AR (1) AR012602A1 (xx)
AT (1) ATE210661T1 (xx)
AU (1) AU734394B2 (xx)
BR (1) BR9808725A (xx)
CA (1) CA2287999A1 (xx)
DE (1) DE69802923T2 (xx)
DK (1) DK0983266T3 (xx)
EE (1) EE9900475A (xx)
ES (1) ES2168757T3 (xx)
HU (1) HUP0003766A3 (xx)
ID (1) ID23156A (xx)
IL (1) IL132677A0 (xx)
IS (1) IS5237A (xx)
MX (1) MXPA99009874A (xx)
NO (1) NO995404L (xx)
NZ (1) NZ500676A (xx)
PL (1) PL336854A1 (xx)
PT (1) PT983266E (xx)
SE (1) SE9701682D0 (xx)
SK (1) SK140699A3 (xx)
TR (1) TR199902719T2 (xx)
WO (1) WO1998050380A1 (xx)
ZA (1) ZA983740B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001024826A2 (en) * 1999-10-06 2001-04-12 The Brigham And Women's Hospital, Inc. Inrease of enos activity through activation of the pi3-kinase/akt pathway by estrogens
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
ZA200709038B (en) 2005-04-13 2009-01-28 Neuraxon Inc Substituted indole compounds having nos inhibitory activity
CL2008000838A1 (es) * 2007-03-23 2008-10-10 Neuraxon Inc Compuestos derivados de quinolina y tetrahidroquinolina, con actividad inhibidora nos; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un dolor de cabeza tal como migrana, dolor cronico, desordenes del sistema nervios
NZ586082A (en) 2007-11-16 2013-03-28 Neuraxon Inc Indole compounds and methods for treating visceral pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504278A (ja) * 1944-06-01 1997-04-28 ザ、ウェルカム、ファンデーション、リミテッド Ｎｏシンターゼインヒビターとしての置換尿素およびイソチオ尿素誘導体
ATE231126T1 (de) * 1993-08-12 2003-02-15 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease- aktivität
ATE177078T1 (de) * 1993-10-21 1999-03-15 Searle & Co Amidino-derivate als no-synthetase inhibitoren
MX9605366A (es) * 1994-05-07 1997-12-31 Astra Ab Derivados de amidina biciclicos como inhibidores de la oxido nitrico sintetasa.
CZ287969B6 (cs) * 1995-08-10 2001-03-14 Astra Pharmaceuticals Limited Amidinový derivát, způsob jeho přípravy, farmaceutický prostředek s jeho obsahem a použití

Also Published As

Publication number Publication date
AU7460098A (en) 1998-11-27
PT983266E (pt) 2002-05-31
EP0983266A1 (en) 2000-03-08
IS5237A (is) 1999-11-01
PL336854A1 (en) 2000-07-17
ID23156A (id) 2000-03-23
DK0983266T3 (da) 2002-03-11
ATE210661T1 (de) 2001-12-15
HUP0003766A2 (en) 2001-03-28
BR9808725A (pt) 2000-07-11
EP0983266B1 (en) 2001-12-12
KR20010012227A (ko) 2001-02-15
ZA983740B (en) 1999-02-19
ES2168757T3 (es) 2002-06-16
AU734394B2 (en) 2001-06-14
AR012602A1 (es) 2000-11-08
MXPA99009874A (es) 2004-09-30
TR199902719T2 (xx) 2000-02-21
NZ500676A (en) 2001-05-25
EE9900475A (et) 2000-06-15
DE69802923D1 (de) 2002-01-24
US6166030A (en) 2000-12-26
JP2001523263A (ja) 2001-11-20
WO1998050380A1 (en) 1998-11-12
DE69802923T2 (de) 2002-07-04
SK140699A3 (en) 2000-06-12
CN1255130A (zh) 2000-05-31
IL132677A0 (en) 2001-03-19
NO995404L (no) 2000-01-05
CA2287999A1 (en) 1998-11-12
HUP0003766A3 (en) 2001-09-28
NO995404D0 (no) 1999-11-04

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