DK0983266T3 - Hidtil ukendte tetrahydrosioquinolinthiophencarboximidamider - Google Patents

Hidtil ukendte tetrahydrosioquinolinthiophencarboximidamider

Info

Publication number
DK0983266T3
DK0983266T3 DK98921953T DK98921953T DK0983266T3 DK 0983266 T3 DK0983266 T3 DK 0983266T3 DK 98921953 T DK98921953 T DK 98921953T DK 98921953 T DK98921953 T DK 98921953T DK 0983266 T3 DK0983266 T3 DK 0983266T3
Authority
DK
Denmark
Prior art keywords
tetrahydrosioquinolinthiophenecarboximidamides
new
new tetrahydrosioquinolinthiophenecarboximidamides
Prior art date
Application number
DK98921953T
Other languages
English (en)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0983266T3 publication Critical patent/DK0983266T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98921953T 1997-05-05 1998-04-28 Hidtil ukendte tetrahydrosioquinolinthiophencarboximidamider DK0983266T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds
PCT/SE1998/000792 WO1998050380A1 (en) 1997-05-05 1998-04-28 Compounds

Publications (1)

Publication Number Publication Date
DK0983266T3 true DK0983266T3 (da) 2002-03-11

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98921953T DK0983266T3 (da) 1997-05-05 1998-04-28 Hidtil ukendte tetrahydrosioquinolinthiophencarboximidamider

Country Status (28)

Country Link
US (1) US6166030A (da)
EP (1) EP0983266B1 (da)
JP (1) JP2001523263A (da)
KR (1) KR20010012227A (da)
CN (1) CN1255130A (da)
AR (1) AR012602A1 (da)
AT (1) ATE210661T1 (da)
AU (1) AU734394B2 (da)
BR (1) BR9808725A (da)
CA (1) CA2287999A1 (da)
DE (1) DE69802923T2 (da)
DK (1) DK0983266T3 (da)
EE (1) EE9900475A (da)
ES (1) ES2168757T3 (da)
HU (1) HUP0003766A3 (da)
ID (1) ID23156A (da)
IL (1) IL132677A0 (da)
IS (1) IS5237A (da)
MX (1) MXPA99009874A (da)
NO (1) NO995404L (da)
NZ (1) NZ500676A (da)
PL (1) PL336854A1 (da)
PT (1) PT983266E (da)
SE (1) SE9701682D0 (da)
SK (1) SK140699A3 (da)
TR (1) TR199902719T2 (da)
WO (1) WO1998050380A1 (da)
ZA (1) ZA983740B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001024826A2 (en) * 1999-10-06 2001-04-12 The Brigham And Women's Hospital, Inc. Inrease of enos activity through activation of the pi3-kinase/akt pathway by estrogens
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
CA2605073C (en) 2005-04-13 2017-12-12 Neuraxon, Inc. Substituted indole compounds having nos inhibitory activity
TWI417099B (zh) * 2007-03-23 2013-12-01 Neuraxon Inc 具抑制一氧化氮合成酶活性之喹諾酮、四氫喹啉及其相關化合物
NZ586082A (en) 2007-11-16 2013-03-28 Neuraxon Inc Indole compounds and methods for treating visceral pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE231126T1 (de) * 1993-08-12 2003-02-15 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease- aktivität
EP0723438A1 (en) * 1993-10-04 1996-07-31 The Wellcome Foundation Limited Substituted urea and isothiourea derivatives as no synthase inhibitors
EP0897912A1 (en) * 1993-10-21 1999-02-24 G.D. Searle & Co. Amidino derivatives useful as nitric oxide synthase inhibitors
US5807886A (en) * 1994-05-07 1998-09-15 Astra Aktiebolag Bicyclic amidine dervatives as inhibitors of nitric oxide synthetase
EE9700207A (et) * 1995-08-10 1998-02-16 Astra Aktiebolag Teraapias kasutatavad bitsüklilised amidiini derivaadid

Also Published As

Publication number Publication date
DE69802923T2 (de) 2002-07-04
EP0983266B1 (en) 2001-12-12
CA2287999A1 (en) 1998-11-12
ES2168757T3 (es) 2002-06-16
HUP0003766A3 (en) 2001-09-28
JP2001523263A (ja) 2001-11-20
IL132677A0 (en) 2001-03-19
ATE210661T1 (de) 2001-12-15
SK140699A3 (en) 2000-06-12
BR9808725A (pt) 2000-07-11
KR20010012227A (ko) 2001-02-15
PL336854A1 (en) 2000-07-17
EP0983266A1 (en) 2000-03-08
NZ500676A (en) 2001-05-25
CN1255130A (zh) 2000-05-31
TR199902719T2 (xx) 2000-02-21
AU734394B2 (en) 2001-06-14
US6166030A (en) 2000-12-26
AR012602A1 (es) 2000-11-08
DE69802923D1 (de) 2002-01-24
NO995404L (no) 2000-01-05
AU7460098A (en) 1998-11-27
WO1998050380A1 (en) 1998-11-12
MXPA99009874A (es) 2004-09-30
SE9701682D0 (sv) 1997-05-05
PT983266E (pt) 2002-05-31
IS5237A (is) 1999-11-01
EE9900475A (et) 2000-06-15
HUP0003766A2 (en) 2001-03-28
ZA983740B (en) 1999-02-19
NO995404D0 (no) 1999-11-04
ID23156A (id) 2000-03-23

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