ID24430A - Turunan-turunan benzamidina - Google Patents
Turunan-turunan benzamidinaInfo
- Publication number
- ID24430A ID24430A IDW20000609A ID20000609A ID24430A ID 24430 A ID24430 A ID 24430A ID W20000609 A IDW20000609 A ID W20000609A ID 20000609 A ID20000609 A ID 20000609A ID 24430 A ID24430 A ID 24430A
- Authority
- ID
- Indonesia
- Prior art keywords
- benzamidina
- benzamidina down
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19743435A DE19743435A1 (de) | 1997-10-01 | 1997-10-01 | Benzamidinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID24430A true ID24430A (id) | 2000-07-20 |
Family
ID=7844313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20000609A ID24430A (id) | 1997-10-01 | 1998-09-16 | Turunan-turunan benzamidina |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6492368B1 (id) |
| EP (1) | EP1025086B1 (id) |
| JP (1) | JP2001518467A (id) |
| KR (1) | KR20010024386A (id) |
| CN (1) | CN1272107A (id) |
| AR (1) | AR017164A1 (id) |
| AT (1) | ATE243681T1 (id) |
| AU (1) | AU736080B2 (id) |
| BR (1) | BR9812699A (id) |
| CA (1) | CA2305568A1 (id) |
| DE (2) | DE19743435A1 (id) |
| HU (1) | HUP0004306A3 (id) |
| ID (1) | ID24430A (id) |
| NO (1) | NO20001687D0 (id) |
| PL (1) | PL339173A1 (id) |
| RU (1) | RU2194044C2 (id) |
| SK (1) | SK282799B6 (id) |
| WO (1) | WO1999016751A1 (id) |
| ZA (1) | ZA988937B (id) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69833036T2 (de) * | 1997-09-30 | 2006-06-22 | Daiichi Pharmaceutical Co., Ltd. | Sulfonylderivate |
| GB9809349D0 (en) | 1998-05-02 | 1998-07-01 | Zeneca Ltd | Heterocyclic derivatives |
| DE69921994T2 (de) * | 1998-05-02 | 2005-12-01 | Astrazeneca Ab | Heterozyklische verbindungen mit faktor xa hemmender wirkung |
| CA2340100A1 (en) * | 1998-08-11 | 2000-02-24 | Daiichi Pharmaceutical Co., Ltd. | Novel sulfonyl derivatives |
| EP1088821A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives |
| EP1829535A3 (en) * | 1999-10-27 | 2007-10-24 | Tanox, Inc. | Tissue factor antagonists and methods of use thereof |
| EP1223921A2 (en) * | 1999-10-27 | 2002-07-24 | Sunol Molecular Corporation | Tissue factor antagonists and methods of use thereof |
| DE10035928A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| DE10035927A1 (de) | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
| EP1193256A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins |
| EP1193267A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active hydrophilic sulfonamide derivatives as inhibitors of protein JunKinases |
| EP1193268A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases |
| WO2002036587A2 (en) | 2000-11-01 | 2002-05-10 | Cor Therapeutics, Inc. | Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides |
| DE10102322A1 (de) | 2001-01-19 | 2002-07-25 | Merck Patent Gmbh | Phenylderivate |
| DE10130718A1 (de) * | 2001-06-26 | 2003-01-02 | Merck Patent Gmbh | Kohlenhydratderivate |
| CN100445276C (zh) | 2002-03-13 | 2008-12-24 | 詹森药业有限公司 | 用作组蛋白去乙酰酶抑制剂的磺酰基衍生物 |
| EA007272B1 (ru) | 2002-03-13 | 2006-08-25 | Янссен Фармацевтика Н. В. | Новые ингибиторы гистондеацетилазы |
| DK1569912T3 (en) | 2002-12-03 | 2015-06-29 | Pharmacyclics Inc | 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors. |
| TW200633990A (en) | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| CA2589748C (en) * | 2004-12-24 | 2013-08-13 | Astrazeneca Ab | Heterocyclic compounds as ccr2b antagonists |
| WO2007007588A1 (ja) * | 2005-07-08 | 2007-01-18 | Ono Pharmaceutical Co., Ltd. | 平面性を有する環状基を母核とする化合物 |
| WO2007070506A2 (en) * | 2005-12-14 | 2007-06-21 | Amgen Inc. | Diaza heterocyclic sulfonamide derivatives and their uses |
| GB0525957D0 (en) | 2005-12-21 | 2006-02-01 | Astrazeneca Ab | Methods |
| EP1968961A2 (en) | 2005-12-21 | 2008-09-17 | Decode Genetics EHF | Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation |
| ES2614931T3 (es) | 2006-08-04 | 2017-06-02 | Beth Israel Deaconess Medical Center | Inhibidores de la piruvato cinasa y métodos de tratamiento de enfermedad |
| JP5464709B2 (ja) | 2007-06-08 | 2014-04-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ピペリジン／ピペラジン誘導体 |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
| AU2008258487B2 (en) * | 2007-06-08 | 2012-11-15 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| CA2687912C (en) | 2007-06-08 | 2015-11-03 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| MX2010002258A (es) | 2007-08-27 | 2010-04-22 | Helicon Therapeutics Inc | Compuestos terapeuticos de isoxazol. |
| CN101796026B (zh) * | 2007-09-07 | 2013-10-23 | 施万制药 | 可用作毒蕈碱受体拮抗剂的含胍化合物 |
| WO2009038021A1 (ja) | 2007-09-21 | 2009-03-26 | Banyu Pharmaceutical Co., Ltd. | ４－スルホニルピペリジン誘導体 |
| AU2009253892B2 (en) | 2008-06-05 | 2015-07-30 | Janssen Pharmaceutica Nv | Drug combinations comprising a DGAT inhibitor and a PPAR-agonist |
| US20100152197A1 (en) * | 2008-12-15 | 2010-06-17 | Astrazeneca Ab | (4-tert-butylpiperazin-2-yl)(piperazin-1-yl)methanone-n-carboxamide derivatives |
| NZ595263A (en) | 2009-02-26 | 2013-06-28 | Compositions, synthesis, and methods of utilizing arylpiperazine derivatives | |
| AU2010234526B2 (en) | 2009-04-06 | 2016-07-21 | Agios Pharmaceuticals, Inc. | Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use |
| TWI598337B (zh) | 2009-06-29 | 2017-09-11 | 阿吉歐斯製藥公司 | 治療化合物及組成物 |
| DK2448581T3 (en) * | 2009-06-29 | 2017-03-13 | Agios Pharmaceuticals Inc | Therapeutic compositions and methods for their applications |
| CA2821975A1 (en) | 2010-12-17 | 2012-06-21 | Shunqi Yan | N-(4-(azetidine-1-carbonyl)phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase m2 pkm2 modulators |
| ES2569712T3 (es) | 2010-12-21 | 2016-05-12 | Agios Pharmaceuticals, Inc. | Activadores de PKM2 bicíclicos |
| TWI549947B (zh) | 2010-12-29 | 2016-09-21 | 阿吉歐斯製藥公司 | 治療化合物及組成物 |
| WO2012151440A1 (en) | 2011-05-03 | 2012-11-08 | Agios Pharmaceuticals, Inc. | Pyruvate kinase activators for use for increasing lifetime of the red blood cells and treating anemia |
| KR101873543B1 (ko) | 2011-05-03 | 2018-07-02 | 아지오스 파마슈티컬스 아이엔씨. | 치료에 사용하기 위한 피루베이트 키나아제 활성제 |
| FR2976943B1 (fr) * | 2011-06-23 | 2013-07-12 | Metabolys | Derives de piperazine, leurs procedes de preparation et leurs utilisations dans le traitement de l'insulinoresistance |
| AU2014249003A1 (en) * | 2013-03-13 | 2015-10-15 | Forma Therapeutics, Inc. | Novel compounds and compositions for inhibition of FASN |
| MX2015011677A (es) | 2013-03-14 | 2016-07-08 | Celtaxsys Inc | Inhibidores de leucotrieno a4 hidrolasa. |
| WO2014139144A1 (en) | 2013-03-15 | 2014-09-18 | Agios Pharmaceuticals, Inc. | Therapeutic compounds and compositions |
| JP6412553B2 (ja) | 2013-03-21 | 2018-10-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | Ｆａｓｎ阻害剤としてのピペラジン誘導体 |
| MD3307271T2 (ro) | 2015-06-11 | 2024-01-31 | Agios Pharmaceuticals Inc | Metode de utilizare a activatorilor de piruvat kinază |
| TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
| US10793554B2 (en) | 2018-10-29 | 2020-10-06 | Forma Therapeutics, Inc. | Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0511347A1 (de) * | 1990-11-15 | 1992-11-04 | Pentapharm A.G. | Meta-substituierte phenylalanin-derivate |
| ZA928276B (en) | 1991-10-31 | 1993-05-06 | Daiichi Seiyaku Co | Aromatic amidine derivates and salts thereof. |
| GB9208740D0 (en) * | 1992-04-23 | 1992-06-10 | Glaxo Group Ltd | Chemical compounds |
| DE4234295A1 (de) * | 1992-10-12 | 1994-04-14 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE4302485A1 (de) * | 1993-01-29 | 1994-08-04 | Merck Patent Gmbh | Piperazinderivate |
| EP3103799B1 (en) | 1995-03-30 | 2018-06-06 | OSI Pharmaceuticals, LLC | Quinazoline derivatives |
| AU6318896A (en) * | 1995-07-06 | 1997-02-05 | Japan Tobacco Inc. | Benzamidoxime derivatives and medicinal use thereof |
| CA2197364A1 (en) * | 1996-02-15 | 1997-08-16 | Toshikazu Suzuki | Phenol compound and process for preparing the same |
| DE69835430T2 (de) * | 1997-05-30 | 2007-03-08 | Takeda Pharmaceutical Co. Ltd. | Sulfonamidderivate, ihre herstellung und verwendung |
-
1997
- 1997-10-01 DE DE19743435A patent/DE19743435A1/de not_active Withdrawn
-
1998
- 1998-09-16 US US09/509,729 patent/US6492368B1/en not_active Expired - Fee Related
- 1998-09-16 PL PL98339173A patent/PL339173A1/xx unknown
- 1998-09-16 AT AT98948982T patent/ATE243681T1/de not_active IP Right Cessation
- 1998-09-16 WO PCT/EP1998/005898 patent/WO1999016751A1/de not_active Application Discontinuation
- 1998-09-16 EP EP98948982A patent/EP1025086B1/de not_active Expired - Lifetime
- 1998-09-16 SK SK447-2000A patent/SK282799B6/sk unknown
- 1998-09-16 AU AU95407/98A patent/AU736080B2/en not_active Ceased
- 1998-09-16 HU HU0004306A patent/HUP0004306A3/hu unknown
- 1998-09-16 DE DE59808842T patent/DE59808842D1/de not_active Expired - Fee Related
- 1998-09-16 BR BR9812699-7A patent/BR9812699A/pt not_active IP Right Cessation
- 1998-09-16 KR KR1020007003536A patent/KR20010024386A/ko not_active Application Discontinuation
- 1998-09-16 CN CN98809650A patent/CN1272107A/zh active Pending
- 1998-09-16 RU RU2000110737/04A patent/RU2194044C2/ru not_active IP Right Cessation
- 1998-09-16 CA CA002305568A patent/CA2305568A1/en not_active Abandoned
- 1998-09-16 ID IDW20000609A patent/ID24430A/id unknown
- 1998-09-16 JP JP2000513837A patent/JP2001518467A/ja active Pending
- 1998-09-29 AR ARP980104841A patent/AR017164A1/es not_active Application Discontinuation
- 1998-09-30 ZA ZA988937A patent/ZA988937B/xx unknown
-
2000
- 2000-03-31 NO NO20001687A patent/NO20001687D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE19743435A1 (de) | 1999-04-08 |
| PL339173A1 (en) | 2000-12-04 |
| DE59808842D1 (de) | 2003-07-31 |
| ZA988937B (en) | 1999-03-31 |
| ATE243681T1 (de) | 2003-07-15 |
| AU736080B2 (en) | 2001-07-26 |
| CA2305568A1 (en) | 1999-04-08 |
| NO20001687L (no) | 2000-03-31 |
| HUP0004306A3 (en) | 2001-12-28 |
| JP2001518467A (ja) | 2001-10-16 |
| US6492368B1 (en) | 2002-12-10 |
| NO20001687D0 (no) | 2000-03-31 |
| RU2194044C2 (ru) | 2002-12-10 |
| EP1025086A1 (de) | 2000-08-09 |
| EP1025086B1 (de) | 2003-06-25 |
| CN1272107A (zh) | 2000-11-01 |
| SK4472000A3 (en) | 2000-11-07 |
| AU9540798A (en) | 1999-04-23 |
| AR017164A1 (es) | 2001-08-22 |
| BR9812699A (pt) | 2000-08-22 |
| KR20010024386A (ko) | 2001-03-26 |
| WO1999016751A1 (de) | 1999-04-08 |
| SK282799B6 (sk) | 2002-12-03 |
| HUP0004306A2 (hu) | 2001-11-28 |
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