SI9720047A - Nove spojine in sestavki za zdravljenje bolezni, povezanih z delovanjem triptaze - Google Patents
Nove spojine in sestavki za zdravljenje bolezni, povezanih z delovanjem triptaze Download PDFInfo
- Publication number
- SI9720047A SI9720047A SI9720047A SI9720047A SI9720047A SI 9720047 A SI9720047 A SI 9720047A SI 9720047 A SI9720047 A SI 9720047A SI 9720047 A SI9720047 A SI 9720047A SI 9720047 A SI9720047 A SI 9720047A
- Authority
- SI
- Slovenia
- Prior art keywords
- alkylene
- compound
- hetero
- formula
- piperazinecarboxylate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
- C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D233/14—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2313996P | 1996-07-30 | 1996-07-30 | |
| US89577297A | 1997-07-17 | 1997-07-17 | |
| PCT/US1997/013422 WO1998004537A1 (en) | 1996-07-30 | 1997-07-30 | Novel compounds and compositions for treating diseases associated with tryptase activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI9720047A true SI9720047A (sl) | 1999-08-31 |
Family
ID=26696778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9720047A SI9720047A (sl) | 1996-07-30 | 1997-07-30 | Nove spojine in sestavki za zdravljenje bolezni, povezanih z delovanjem triptaze |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0934293A1 (sv) |
| JP (1) | JP2001509787A (sv) |
| KR (1) | KR20000029679A (sv) |
| CN (1) | CN1073103C (sv) |
| AU (1) | AU733621B2 (sv) |
| CA (1) | CA2262542A1 (sv) |
| CZ (1) | CZ29799A3 (sv) |
| EE (1) | EE9900036A (sv) |
| FI (1) | FI990171A (sv) |
| HU (1) | HUP0003267A3 (sv) |
| LV (1) | LV12291B (sv) |
| NO (1) | NO990433L (sv) |
| NZ (1) | NZ333713A (sv) |
| PL (1) | PL331465A1 (sv) |
| SI (1) | SI9720047A (sv) |
| SK (1) | SK8599A3 (sv) |
| WO (1) | WO1998004537A1 (sv) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221914B1 (en) | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| EP1060171A2 (de) * | 1998-02-06 | 2000-12-20 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tryptase-inhibitoren |
| ES2233025T3 (es) * | 1998-02-06 | 2005-06-01 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Agente inhibidores de la triptasa. |
| AU5625499A (en) * | 1998-09-04 | 2000-03-27 | Altana Pharma Ag | Novel pyranoses |
| DE60014932T2 (de) | 1999-08-10 | 2005-10-13 | Altana Pharma Ag | Diazocindionderivate und ihre verwendung als tryptase inhibitoren |
| AU778965B2 (en) * | 1999-09-14 | 2004-12-23 | Altana Pharma Ag | Tryptase inhibitors |
| WO2001036386A1 (fr) * | 1999-11-17 | 2001-05-25 | Sumitomo Pharmaceuticals Co., Ltd. | Traitement du diabete contenant un derive de dipiperazine |
| DE19955476A1 (de) * | 1999-11-18 | 2001-05-23 | Boehringer Ingelheim Pharma | Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| CA2392127A1 (en) | 1999-12-20 | 2001-06-28 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tryptase inhibitors |
| TR200402322T4 (tr) * | 1999-12-20 | 2004-12-21 | Altana Pharma Ag | Triptaz inhibitörler |
| DK1358182T3 (da) * | 2001-01-31 | 2004-12-20 | Altana Pharma Ag | Diazocin-derivater og anvendelsen deraf som tryptase-inhibitorer |
| ATE349427T1 (de) | 2001-02-21 | 2007-01-15 | Altana Pharma Ag | Tryptaseinhibitoren |
| CA2438711A1 (en) | 2001-02-21 | 2002-08-29 | Altana Pharma Ag | Tryptase inhibitors |
| US20040087792A1 (en) * | 2001-03-15 | 2004-05-06 | Thomas Martin | Tryptase-inhibitors |
| WO2002074732A2 (en) * | 2001-03-15 | 2002-09-26 | Altana Pharma Ag | Tryptase-inhibitors |
| AU2002345664C1 (en) | 2001-06-11 | 2008-03-06 | Xenoport, Inc. | Prodrugs of gaba analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| ES2278928T3 (es) | 2001-06-19 | 2007-08-16 | Altana Pharma Ag | Inhibidores de triptasa. |
| WO2006050514A1 (en) | 2004-11-04 | 2006-05-11 | Xenoport, Inc. | Gabapentin prodrug sustained release oral dosage forms |
| TWI432188B (zh) | 2008-12-19 | 2014-04-01 | Merz Pharma Gmbh & Co Kgaa | 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類 |
| AU2009328497A1 (en) | 2008-12-19 | 2010-06-24 | Merz Pharma Gmbh & Co. Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases |
| FR3038605B1 (fr) | 2015-07-06 | 2018-08-24 | Universite Amiens Picardie Jules Verne | Diamines primaires vicinales associees a des motifs chelateurs de metaux et/ou de radicaux libres, actives contre les stress carbonyle et oxydant et leur utilisation |
| CN110869362A (zh) * | 2017-05-12 | 2020-03-06 | 国立研究开发法人理化学研究所 | A类gpcr结合性化合物改性体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845242A (en) * | 1987-04-28 | 1989-07-04 | Georgia Tech Research Corporation | Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents |
| JPH08507768A (ja) * | 1993-03-12 | 1996-08-20 | アリス ファーマシューティカル コーポレイション | 免疫仲介炎症疾患の処置のための組成物および方法 |
| US5525623A (en) * | 1993-03-12 | 1996-06-11 | Arris Pharmaceutical Corporation | Compositions and methods for the treatment of immunomediated inflammatory disorders |
| JPH10501238A (ja) * | 1994-06-01 | 1998-02-03 | アリス ファーマシューティカル コーポレイション | 肥満細胞媒介症状を治療するための組成物及び方法 |
| SI9520101A (en) * | 1994-09-23 | 1997-12-31 | Arris Pharm Corp | Compositions and methods for treating mast-cell inflammatory condition |
| KR19980703261A (ko) * | 1995-03-24 | 1998-10-15 | 다니엘 이이치. 페트리 | 가역성 프로테아제 억제제 |
| TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
-
1997
- 1997-07-30 CZ CZ99297A patent/CZ29799A3/cs unknown
- 1997-07-30 EE EEP199900036A patent/EE9900036A/xx unknown
- 1997-07-30 AU AU39670/97A patent/AU733621B2/en not_active Ceased
- 1997-07-30 SI SI9720047A patent/SI9720047A/sl unknown
- 1997-07-30 WO PCT/US1997/013422 patent/WO1998004537A1/en not_active Application Discontinuation
- 1997-07-30 PL PL97331465A patent/PL331465A1/xx unknown
- 1997-07-30 HU HU0003267A patent/HUP0003267A3/hu unknown
- 1997-07-30 EP EP97937066A patent/EP0934293A1/en not_active Withdrawn
- 1997-07-30 NZ NZ333713A patent/NZ333713A/xx unknown
- 1997-07-30 KR KR1019997000757A patent/KR20000029679A/ko not_active Application Discontinuation
- 1997-07-30 CN CN97196877A patent/CN1073103C/zh not_active Expired - Fee Related
- 1997-07-30 CA CA002262542A patent/CA2262542A1/en not_active Abandoned
- 1997-07-30 JP JP50913698A patent/JP2001509787A/ja active Pending
- 1997-07-30 SK SK85-99A patent/SK8599A3/sk unknown
-
1999
- 1999-01-29 NO NO990433A patent/NO990433L/no not_active Application Discontinuation
- 1999-01-29 FI FI990171A patent/FI990171A/sv unknown
- 1999-02-18 LV LVP-99-27A patent/LV12291B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU733621B2 (en) | 2001-05-17 |
| JP2001509787A (ja) | 2001-07-24 |
| FI990171A (sv) | 1999-03-23 |
| FI990171A0 (sv) | 1999-01-29 |
| HUP0003267A3 (en) | 2002-02-28 |
| NO990433D0 (no) | 1999-01-29 |
| CN1226892A (zh) | 1999-08-25 |
| AU3967097A (en) | 1998-02-20 |
| CN1073103C (zh) | 2001-10-17 |
| SK8599A3 (en) | 2000-03-13 |
| LV12291A (lv) | 1999-06-20 |
| CA2262542A1 (en) | 1998-02-05 |
| NZ333713A (en) | 2000-12-22 |
| PL331465A1 (en) | 1999-07-19 |
| KR20000029679A (ko) | 2000-05-25 |
| EP0934293A1 (en) | 1999-08-11 |
| EE9900036A (et) | 1999-08-16 |
| NO990433L (no) | 1999-03-25 |
| CZ29799A3 (cs) | 1999-06-16 |
| HUP0003267A2 (hu) | 2001-06-28 |
| LV12291B (en) | 2000-04-20 |
| WO1998004537A1 (en) | 1998-02-05 |
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